KCNJ10 (kir4.1) potassium channel knockout abolishes endocochlear potential

American Journal of Physiology - Cell Physiology

Volumn 282, Issue 2 51-2, 2002, Pages

  Marcus, Daniel C ^a   Wu, Tao ^a   Wangemann, Philine ^a   Kofuji, Paulo ^b  

^a KANSAS STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Mouse; Null mutation; Potassium secretion; Stria vascularis; Transepithelial potential

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM ION;

ANIMAL CELL; ARTICLE; BASAL CELL; COCHLEA POTENTIAL; CONTROLLED STUDY; ENDOLYMPH; GAP JUNCTION; GENE MUTATION; HEARING; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRIA VASCULARIS;

ANIMALIA;

EID: 0036086734     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00312.2001     Document Type: Article

References (30)

1. + channel (Kir4.1) in the intermediate cell (melanocyte) of the cochlear stria vascularis of gerbils and rats
2. Endocochlear potential generation is associated with intercellular communication in the stria vascularis: Structural analysis in the viable dominant spotting mouse mutant
3. Immunohistochemical localization of the Na-K-Cl co-transporter (NKCC1) in the gerbil inner ear
4. Overview: Cochlear neurobiology
5. Deafness and imbalance associated with inactivation of the secretory NaK-2Cl co-transporter
6. AB-2 (Kir4.1), in cochlear stria vascularis of inner ear: Its specific subcellular localization and correlation with the formation of endocochlear potential
7. Clustering and enhanced activity of an inwardly rectifying potassium channel, Kir4.1, by an anchoring protein, PSD-95/SAP90
8. Expression and clustered distribution of an inwardly rectifying potassium channel, KAB-2/Kir4.1, on mammalian retinal Muller cell membrane: Their regulation by insulin and laminin signals
9. Intercellular junctions in the guinea pig stria vascularis as shown by freeze-etching
10. The use of Preyer's reflex in evaluation of hearing in mice
11. The development of the organ of Corti in the mouse
12. Gap junctions in the rat cochlea: Immunohistochemical and ultrastructural analysis
13. Genetic inactivation of an inwardly rectifying potassium channel (Kir4.1 subunit) in mice: Phenotypic impact in retina
14. Ion transport in guinea pig cochlea. I. Potassium and sodium transport
15. Targeted disruption of the Kvlqt 1 gene causes deafness and gastric hyperplasia in mice
16. Effects of barium and ion substitutions in artificial blood on endocochlear potential
17. Potassium secretion by nonsensory region of gerbil utricle in vitro
18. Development of endocochlear potential and its negative component in mouse cochlea
19. Immunolocalization of ClC-K chloride channel in strial marginal cells and vestibular dark cells
20. Mechanisms of endocochlear potential generation by stria vascularis
21. sK channel in strial marginal cells: Voltage-dependence, ionselectivity, inhibition by 293B and sensitivity to clofilium
22. Another role for melanocytes: Their importance for normal stria vascularis development in the mammalian inner ear
23. + current in intermediate cell of stria vascularis of gerbil cochlea
24. Mechanism generating endocochlear potential: Role played by intermediate cells in stria vascularis
25. Three-dimensional and ultrastructural relationships between intermediate cells and capillaries in the gerbil stria vascularis
26. Stria vascularis as source of endocochlear potential
27. Inner ear defects induced by null mutation of the isk gene
28. Comparison of ion transport mechanisms between vestibular dark cells and strial marginal cells
29. + secretion and the transepithelial voltage across marginal cells of stria vascularis in vitro
30. Development of monovalent ions in the endolymph in mouse cochlea