Endocochlear potential depends on Cl- channels: Mechanism underlying deafness in Bartter syndrome IV

EMBO Journal

Volumn 27, Issue 21, 2008, Pages 2907-2917

  Rickheit, Gesa ^a   Maier, Hannes ^b   Strenzke, Nicola ^c   Andreescu, Corina E ^d   De Zeeuw, Chris I ^d,e   Muenscher, Adrian ^b   Zdebik, Anselm A ^a,f   Jentsch, Thomas J ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Anion transport; Inner ear; Otoacoustic emission; Potassium recycling; Sox10

Indexed keywords

BARTTIN; CHLORIDE CHANNEL; GENE PRODUCT; POTASSIUM; PROTEIN BSND; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; BARTTER SYNDROME IV; BETA CHAIN; BSND GENE; CELL TYPE; COCHLEA; COCHLEA POTENTIAL; CONGENITAL DEAFNESS; DEHYDRATION; DISEASE ACTIVITY; EPITHELIUM; EVOKED BRAIN STEM AUDITORY RESPONSE; GENE; GENE DELETION; GENE DISRUPTION; GENE MUTATION; HAIR CELL; INNER EAR; KIDNEY; MOUSE; NONHUMAN; PATHOGENESIS; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN FUNCTION; SENSORY NERVE CELL; SODIUM DEPLETION; STRIA VASCULARIS; THICKNESS; TIGHT JUNCTION; VESTIBULAR SYSTEM; VESTIBULE AQUEDUCT;

ANIMALS; BARTTER SYNDROME; CHLORIDE CHANNELS; COCHLEA; DEAFNESS; DNA-BINDING PROTEINS; ENDOLYMPH; EVOKED POTENTIALS; GENE DELETION; HAIR CELLS, AUDITORY; HIGH MOBILITY GROUP PROTEINS; HUMANS; INTEGRASES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; STRIA VASCULARIS; TRANSCRIPTION FACTORS; VESTIBULE, LABYRINTH;

EPITONIUM; MUS;

EID: 55549109716     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2008.203     Document Type: Article

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