Deficiency of sphingomyelin synthase-1 but not sphingomyelin synthase-2 causes hearing impairments in mice

Journal of Physiology

Volumn 590, Issue 16, 2012, Pages 4029-4044

  Lu, Mei Hong ^a   Takemoto, Makoto ^a   Watanabe, Ken ^b   Luo, Huan ^a   Nishimura, Masataka ^a   Yano, Masato ^a   Tomimoto, Hidekazu ^c   Okazaki, Toshiro ^d   Oike, Yuichi ^a   Song, Wen Jie ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^c MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d KANAZAWA MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

POTASSIUM CHANNEL KCNQ1; SPHINGOMYELIN SYNTHASE 1; SPHINGOMYELIN SYNTHASE 2; SYNTHETASE; UNCLASSIFIED DRUG;

ACOUSTIC ANALYSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY STIMULATION; CELL DENSITY; CELL INVASION; CELLULAR DISTRIBUTION; COCHLEA POTENTIAL; CONTROLLED STUDY; DISTORTION PRODUCT OTOACOUSTIC EMISSION; DOWN REGULATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; EVOKED BRAIN STEM AUDITORY RESPONSE; FREQUENCY MODULATION; HAIR CELL; HEARING LOSS; HISTOPATHOLOGY; KNOCKOUT MOUSE; MACROPHAGE; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; STRIA VASCULARIS;

ANIMALS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEARING LOSS; MICE; MICE, KNOCKOUT; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

EID: 84865630165     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2012.235846     Document Type: Article

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