Perivascular-resident macrophage-like melanocytes in the inner ear are essential for the integrity of the intrastrial fluid-blood barrier

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 26, 2012, Pages 10388-10393

  Zhang, Wenjing ^a,b   Dai, Min ^a   Fridberger, Anders ^c   Hassan, Ahmed ^d   DeGagne, Jacqueline ^a   Neng, Lingling ^a,b   Zhang, Fei ^a   He, Wenxuan ^a   Ren, Tianying ^a   Trune, Dennis ^a   Auer, Manfred ^d   Shi, Xiaorui ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b ZHENGZHOU UNIVERSITY   (China)

^c KAROLINSKA INSTITUTE   (Sweden)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

Capillary; Mouse cochlea; Paracellular permeability; Tight junction

Indexed keywords

PIGMENT EPITHELIUM DERIVED FACTOR; TRACER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDITORY THRESHOLD; BLOOD CEREBROSPINAL FLUID BARRIER; BLOOD VESSEL PERMEABILITY; CELL CULTURE; COCHLEA POTENTIAL; CONTROLLED STUDY; EVOKED BRAIN STEM AUDITORY RESPONSE; HEARING; HEARING LOSS; IN VITRO STUDY; INNER EAR; MACROPHAGE; MALE; MELANOCYTE; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIGHT JUNCTION;

ANIMALS; EAR, INNER; HUMANS; MACROPHAGES; MELANOCYTES; MICE; MICE, TRANSGENIC; STRIA VASCULARIS; TIGHT JUNCTIONS;

ANIMALIA;

EID: 84862975929     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1205210109     Document Type: Article

References (34)

1. Juhn SK, Hunter BA, Odland RM (2001) Blood-labyrinth barrier and fluid dynamics of the inner ear. Int Tinnitus J 7:72-83. (Pubitemid 34174357)
2. Juhn SK, Rybak LP, Prado S (1981) Nature of blood-labyrinth barrier in experimental conditions. Ann Otol Rhinol Laryngol 90:135-141. (Pubitemid 11157160)
3. Salt AN, Melichar I, Thalmann R (1987) Mechanisms of endocochlear potential generation by stria vascularis. Laryngoscope 97:984-991. (Pubitemid 18022613)
4. Takeuchi S, Ando M, Sato T, Kakigi A (2001) Three-dimensional and ultrastructural relationships between intermediate cells and capillaries in the gerbil stria vascularis. Hear Res 155:103-112. (Pubitemid 32401593)
5. Lin DW, Trune DR (1997) Breakdown of stria vascularis blood-labyrinth barrier in C3H/lpr autoimmune disease mice. Otolaryngol Head Neck Surg 117:530-534. (Pubitemid 27508147)
6. Doi K, Mori N, Matsunaga T (1992) Adenylate cyclase modulation of ion permeability in the guinea pig cochlea: A possible mechanism for the formation of endolymphatic hydrops. Acta Otolaryngol 112:667-673.
7. Cohen-Salmon M, et al. (2007) Connexin30 deficiency causes instrastrial fluid-blood barrier disruption within the cochlear stria vascularis. Proc Natl Acad Sci USA 104: 6229-6234. (Pubitemid 47186077)
8. Gratton MA, Schulte BA, Smythe NM (1997) Quantification of the stria vascularis and strial capillary areas in quiet-reared young and aged gerbils. Hear Res 114:1-9. (Pubitemid 28007848)
9. Hukee MJ, Duvall AJ III (1985) Cochlear vessel permeability to horseradish peroxidase in the normal and acoustically traumatized chinchilla: A reevaluation. Ann Otol Rhinol Laryngol 94:297-303. (Pubitemid 15051855)
10. Shi X (2009) Cochlear pericyte responses to acoustic trauma and the involvement of hypoxia-inducible factor-1alpha and vascular endothelial growth factor. Am J Pathol 174:1692-1704.
11. Sakagami M, Matsunaga T, Hashimoto PH (1982) Fine structure and permeability of capillaries in the stria vascularis and spiral ligament of the inner ear of the guinea pig. Cell Tissue Res 226:511-522. (Pubitemid 13199020)
12. Dai M, et al. (2010) Bone marrow cell recruitment mediated by inducible nitric oxide synthase/stromal cell-derived factor-1alpha signaling repairs the acoustically damaged cochlear blood-labyrinth barrier. Am J Pathol 177:3089-3099.
13. Shi X (2010) Resident macrophages in the cochlear blood-labyrinth barrier and their renewal via migration of bone-marrow-derived cells. Cell Tissue Res 342:21-30.
14. Prat A, Biernacki K, Wosik K, Antel JP (2001) Glial cell influence on the human blood-brain barrier. Glia 36:145-155. (Pubitemid 33055903)
15. Pottiez G, Flahaut C, Cecchelli R, Karamanos Y (2009) Understanding the blood-brain barrier using gene and protein expression profiling technologies. Brain Res Brain Res Rev 62:83-98.
16. Abbott NJ, Rönnbäck L, Hansson E (2006) Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci 7:41-53. (Pubitemid 41828930)
17. Duffield JS, et al. (2005) Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J Clin Invest 115:56-65. (Pubitemid 40385505)
18. Hochweller K, Striegler J, Hämmerling GJ, Garbi N (2008) A novel CD11c.DTR transgenic mouse for depletion of dendritic cells reveals their requirement for homeostatic proliferation of natural killer cells. Eur J Immunol 38:2776-2783.
19. Bar-On L, Jung S (2010) Defining dendritic cells by conditional and constitutive cell ablation. Immunol Rev 234:76-89.
20. Le Guelte A, Gavard J (2011) Role of endothelial cell-cell junctions in endothelial permeability. Methods Mol Biol 763:265-279.
21. Kawaguchi T, Yamagishi SI, Sata M (2010) Structure-function relationships of PEDF. Curr Mol Med 10:302-311.
22. Redzic Z (2011) Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: Similarities and differences. Fluids Barriers CNS 8:3.
23. Kitajiri SI, et al. (2004) Expression patterns of claudins, tight junction adhesion molecules, in the inner ear. Hear Res 187:25-34.
24. Yang Y, et al. (2011) Na+/K+-ATPase α1 identified as an abundant protein in the blood-labyrinth barrier that plays an essential role in the barrier integrity. PLoS ONE 6:e16547.
25. Gleich O, Piña AL (2008) Protein expression of pigment-epithelium- derived factor in rat cochlea. Cell Tissue Res 332:565-571.
26. Liu H, et al. (2004) Identification of the antivasopermeability effect of pigment epithelium-derived factor and its active site. Proc Natl Acad Sci USA 101:6605-6610. (Pubitemid 38586021)
27. Ueda S, Yamagishi SI, Okuda S (2010) Anti-vasopermeability effects of PEDF in retinal-renal disorders. Curr Mol Med 10:279-283.
28. Hibino H, et al. (1997) An ATP-dependent inwardly rectifying potassium channel, KAB-2 (Kir4. 1), in cochlear stria vascularis of inner ear: Its specific subcellular localization and correlation with the formation of endocochlear potential. J Neurosci 17:4711-4721. (Pubitemid 27246928)
29. Cable J, Steel KP (1991) Identification of two types of melanocyte within the stria vascularis of the mouse inner ear. Pigment Cell Res 4:87-101.
30. Conlee JW, Parks TN, Schwartz IR, Creel DJ (1989) Comparative anatomy of melanin pigment in the stria vascularis. Evidence for a distinction between melanocytes and intermediate cells in the cat. Acta Otolaryngol 107:48-58. (Pubitemid 19035852)
31. Steel KP, Barkway C (1989) Another role for melanocytes: Their importance for normal stria vascularis development in the mammalian inner ear. Development 107: 453-463. (Pubitemid 20006085)
32. Tachibana M (2001) Cochlear melanocytes and MITF signaling. J Investig Dermatol Symp Proc 6:95-98.
33. Cai J, et al. (2011) γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1. J Biol Chem 286:42514-42523.
34. Sheikpranbabu S, Haribalaganesh R, Lee KJ, Gurunathan S (2010) Pigment epithelium-derived factor inhibits advanced glycation end products-induced retinal vascular permeability. Biochimie 92:1040-1051.