메뉴 건너뛰기




Volumn 99, Issue 9, 2014, Pages 1154-1162

Targeting cellular drivers and counter-regulators of hyperglycaemia- and transforming growth factor-β1-associated profibrotic responses in diabetic kidney disease

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 1 RECEPTOR ANTAGONIST; DIURETIC AGENT; GLUCOSE; LIPOXIN; MICRORNA; TRANSFORMING GROWTH FACTOR BETA1; ANTIDIABETIC AGENT; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; GREM1 PROTEIN, HUMAN; IHG-1 PROTEIN, HUMAN; MIRNLET7 MICRORNA, HUMAN; PROTEIN; SIGNAL PEPTIDE;

EID: 84908298919     PISSN: 09580670     EISSN: 1469445X     Source Type: Journal    
DOI: 10.1113/expphysiol.2014.078774     Document Type: Article
Times cited : (8)

References (58)
  • 1
    • 77955413485 scopus 로고    scopus 로고
    • The magnitude of association between overweight and obesity and the risk of diabetes: a meta-analysis of prospective cohort studies
    • Abdullah A, Peeters A, de Courten M & Stoelwinder J (2010). The magnitude of association between overweight and obesity and the risk of diabetes: a meta-analysis of prospective cohort studies. Diabetes Res Clin Pract 89, 309-319.
    • (2010) Diabetes Res Clin Pract , vol.89 , pp. 309-319
    • Abdullah, A.1    Peeters, A.2    de Courten, M.3    Stoelwinder, J.4
  • 2
    • 0037213037 scopus 로고    scopus 로고
    • Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64)
    • Adler AI, Stevens RJ, Manley SE, Bilous RW, Cull CA & Holman RR; UKPDS Group (2003). Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64). Kidney Int 63, 225-232.
    • (2003) Kidney Int , vol.63 , pp. 225-232
    • Adler, A.I.1    Stevens, R.J.2    Manley, S.E.3    Bilous, R.W.4    Cull, C.A.5    Holman, R.R.6
  • 6
    • 84867394203 scopus 로고    scopus 로고
    • Can we target tubular damage to prevent renal function decline in diabetes?
    • Bonventre JV (2012). Can we target tubular damage to prevent renal function decline in diabetes? Semin Nephrol 32, 452-462.
    • (2012) Semin Nephrol , vol.32 , pp. 452-462
    • Bonventre, J.V.1
  • 11
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M (2001). Biochemistry and molecular cell biology of diabetic complications. Nature 414, 813-820.
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 13
    • 0037155860 scopus 로고    scopus 로고
    • High glucose-altered gene expression in mesangial cells. Actin-regulatory protein gene expression is triggered by oxidative stress and cytoskeletal disassembly
    • Clarkson MR, Murphy M, Gupta S, Lambe T, Mackenzie HS, Godson C, Martin F & Brady HR (2002). High glucose-altered gene expression in mesangial cells. Actin-regulatory protein gene expression is triggered by oxidative stress and cytoskeletal disassembly. J Biol Chem 277, 9707-9712.
    • (2002) J Biol Chem , vol.277 , pp. 9707-9712
    • Clarkson, M.R.1    Murphy, M.2    Gupta, S.3    Lambe, T.4    Mackenzie, H.S.5    Godson, C.6    Martin, F.7    Brady, H.R.8
  • 14
    • 84861695669 scopus 로고    scopus 로고
    • Role of intensive glucose control in development of renal end points in type 2 diabetes mellitus: systematic review and meta-analysis intensive glucose control in type 2 diabetes
    • Coca SG, Ismail-Beigi F, Haq N, Krumholz HM & Parikh CR (2012). Role of intensive glucose control in development of renal end points in type 2 diabetes mellitus: systematic review and meta-analysis intensive glucose control in type 2 diabetes. Arch Intern Med 172, 761-769.
    • (2012) Arch Intern Med , vol.172 , pp. 761-769
    • Coca, S.G.1    Ismail-Beigi, F.2    Haq, N.3    Krumholz, H.M.4    Parikh, C.R.5
  • 16
    • 79959936188 scopus 로고    scopus 로고
    • National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants
    • Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, Lin JK, Farzadfar F, Khang YH, Stevens GA, Rao M, Ali MK, Riley LM, Robinson CA & Ezzati M; Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Glucose) (2011). National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Lancet 378, 31-40.
    • (2011) Lancet , vol.378 , pp. 31-40
    • Danaei, G.1    Finucane, M.M.2    Lu, Y.3    Singh, G.M.4    Cowan, M.J.5    Paciorek, C.J.6    Lin, J.K.7    Farzadfar, F.8    Khang, Y.H.9    Stevens, G.A.10    Rao, M.11    Ali, M.K.12    Riley, L.M.13    Robinson, C.A.14    Ezzati, M.15
  • 21
    • 53349101264 scopus 로고    scopus 로고
    • Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
    • El-Osta A, Brasacchio D, Yao D, Pocai A, Jones PL, Roeder RG, Cooper ME & Brownlee M (2008). Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J Exp Med 205, 2409-2417.
    • (2008) J Exp Med , vol.205 , pp. 2409-2417
    • El-Osta, A.1    Brasacchio, D.2    Yao, D.3    Pocai, A.4    Jones, P.L.5    Roeder, R.G.6    Cooper, M.E.7    Brownlee, M.8
  • 22
    • 0024519220 scopus 로고
    • Specific regulation of intestinal nutrient transporters by their dietary substrates
    • Ferraris RP & Diamond JM (1989). Specific regulation of intestinal nutrient transporters by their dietary substrates. Annu Rev Physiol 51, 125-141.
    • (1989) Annu Rev Physiol , vol.51 , pp. 125-141
    • Ferraris, R.P.1    Diamond, J.M.2
  • 23
    • 21544462572 scopus 로고    scopus 로고
    • Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence
    • Ford ES (2005). Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence. Diabetes Care 28, 1769-1778.
    • (2005) Diabetes Care , vol.28 , pp. 1769-1778
    • Ford, E.S.1
  • 24
    • 38949210220 scopus 로고    scopus 로고
    • Effect of a multifactorial intervention on mortality in type 2 diabetes
    • Gaede P, Lund-Andersen H, Parving HH & Pedersen O (2008). Effect of a multifactorial intervention on mortality in type 2 diabetes. N Engl J Med 358, 580-591.
    • (2008) N Engl J Med , vol.358 , pp. 580-591
    • Gaede, P.1    Lund-Andersen, H.2    Parving, H.H.3    Pedersen, O.4
  • 25
    • 84866732695 scopus 로고    scopus 로고
    • GLP-1 analog liraglutide protects against oxidative stress and albuminuria in streptozotocin-induced diabetic rats via protein kinase A-mediated inhibition of renal NAD(P)H oxidases
    • Hendarto H, Inoguchi T, Maeda Y, Ikeda N, Zheng J, Takei R, Yokomizo H, Hirata E, Sonoda N & Takayanagi R (2012). GLP-1 analog liraglutide protects against oxidative stress and albuminuria in streptozotocin-induced diabetic rats via protein kinase A-mediated inhibition of renal NAD(P)H oxidases. Metabolism 61, 1422-1434.
    • (2012) Metabolism , vol.61 , pp. 1422-1434
    • Hendarto, H.1    Inoguchi, T.2    Maeda, Y.3    Ikeda, N.4    Zheng, J.5    Takei, R.6    Yokomizo, H.7    Hirata, E.8    Sonoda, N.9    Takayanagi, R.10
  • 26
    • 84885960809 scopus 로고    scopus 로고
    • Diabetic kidney disease and immune modulation
    • Hickey FB & Martin F (2013). Diabetic kidney disease and immune modulation. Curr Opin Pharmacol 13, 602-612.
    • (2013) Curr Opin Pharmacol , vol.13 , pp. 602-612
    • Hickey, F.B.1    Martin, F.2
  • 29
    • 84864139464 scopus 로고    scopus 로고
    • MicroRNA circuits in transforming growth factor-β actions and diabetic nephropathy
    • Kato M & Natarajan R (2012). MicroRNA circuits in transforming growth factor-β actions and diabetic nephropathy. Semin Nephrol 32, 253-260.
    • (2012) Semin Nephrol , vol.32 , pp. 253-260
    • Kato, M.1    Natarajan, R.2
  • 30
    • 84885618744 scopus 로고    scopus 로고
    • Metabolic syndrome and associated chronic kidney diseases: nutritional interventions
    • Kumar PA, Chitra PS & Reddy GB (2013). Metabolic syndrome and associated chronic kidney diseases: nutritional interventions. Rev Endocr Metab Disord 14, 273-286.
    • (2013) Rev Endocr Metab Disord , vol.14 , pp. 273-286
    • Kumar, P.A.1    Chitra, P.S.2    Reddy, G.B.3
  • 31
    • 79952654623 scopus 로고    scopus 로고
    • Telmisartan attenuates oxidative stress and renal fibrosis in streptozotocin induced diabetic mice with the alteration of angiotensin-(1-7) mas receptor expression associated with its PPAR-γ agonist action
    • Lakshmanan AP, Watanabe K, Thandavarayan RA, Sari FR, Harima M, Giridharan VV, Soetikno V, Kodama M & Aizawa Y (2011). Telmisartan attenuates oxidative stress and renal fibrosis in streptozotocin induced diabetic mice with the alteration of angiotensin-(1-7) mas receptor expression associated with its PPAR-γ agonist action. Free Radic Res 45, 575-584.
    • (2011) Free Radic Res , vol.45 , pp. 575-584
    • Lakshmanan, A.P.1    Watanabe, K.2    Thandavarayan, R.A.3    Sari, F.R.4    Harima, M.5    Giridharan, V.V.6    Soetikno, V.7    Kodama, M.8    Aizawa, Y.9
  • 32
    • 84864148484 scopus 로고    scopus 로고
    • TGF-β/Smad signaling in kidney disease
    • Lan HY & Chung AC (2012). TGF-β/Smad signaling in kidney disease. Semin Nephrol 32, 236-243.
    • (2012) Semin Nephrol , vol.32 , pp. 236-243
    • Lan, H.Y.1    Chung, A.C.2
  • 33
    • 77958192655 scopus 로고    scopus 로고
    • Cost-effectiveness of interventions to prevent and control diabetes mellitus: a systematic review
    • Li R, Zhang P, Barker LE, Chowdhury FM & Zhang X (2010). Cost-effectiveness of interventions to prevent and control diabetes mellitus: a systematic review. Diabetes Care 33, 1872-1894.
    • (2010) Diabetes Care , vol.33 , pp. 1872-1894
    • Li, R.1    Zhang, P.2    Barker, L.E.3    Chowdhury, F.M.4    Zhang, X.5
  • 35
    • 0034616419 scopus 로고    scopus 로고
    • IHG-2, a mesangial cell gene induced by high glucose, is human gremlin. Regulation by extracellular glucose concentration, cyclic mechanical strain, and transforming growth factor-β1
    • McMahon R, Murphy M, Clarkson M, Taal M, Mackenzie HS, Godson C, Martin F & Brady HR (2000). IHG-2, a mesangial cell gene induced by high glucose, is human gremlin. Regulation by extracellular glucose concentration, cyclic mechanical strain, and transforming growth factor-β1. J Biol Chem 275, 9901-9904.
    • (2000) J Biol Chem , vol.275 , pp. 9901-9904
    • McMahon, R.1    Murphy, M.2    Clarkson, M.3    Taal, M.4    Mackenzie, H.S.5    Godson, C.6    Martin, F.7    Brady, H.R.8
  • 36
    • 84890547453 scopus 로고    scopus 로고
    • The role of glucagon-like peptide-1 impairment in obesity and potential therapeutic implications
    • Madsbad S (2014). The role of glucagon-like peptide-1 impairment in obesity and potential therapeutic implications. Diabetes Obes Metab 16, 9-21.
    • (2014) Diabetes Obes Metab , vol.16 , pp. 9-21
    • Madsbad, S.1
  • 37
    • 84866742560 scopus 로고    scopus 로고
    • TGFβ signalling in context
    • Massagué J (2012). TGFβ signalling in context. Nat Rev Mol Cell Biol 13, 616-630.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 616-630
    • Massagué, J.1
  • 38
  • 40
    • 0033605162 scopus 로고    scopus 로고
    • Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells
    • Murphy M, Godson C, Cannon S, Kato S, Mackenzie HS, Martin F & Brady HR (1999). Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells. J Biol Chem 274, 5830-5834.
    • (1999) J Biol Chem , vol.274 , pp. 5830-5834
    • Murphy, M.1    Godson, C.2    Cannon, S.3    Kato, S.4    Mackenzie, H.S.5    Martin, F.6    Brady, H.R.7
  • 42
    • 84883524268 scopus 로고    scopus 로고
    • Epigenetic modifications in the pathogenesis of diabetic nephropathy
    • Reddy MA, Tak Park J & Natarajan R (2013). Epigenetic modifications in the pathogenesis of diabetic nephropathy. Semin Nephrol 33, 341-353.
    • (2013) Semin Nephrol , vol.33 , pp. 341-353
    • Reddy, M.A.1    Tak Park, J.2    Natarajan, R.3
  • 46
    • 33745435247 scopus 로고    scopus 로고
    • Recapitulation of embryological programmes in renal fibrosis - the importance of epithelial cell plasticity and developmental genes
    • Roxburgh SA, Murphy M, Pollock CA & Brazil DP (2006). Recapitulation of embryological programmes in renal fibrosis - the importance of epithelial cell plasticity and developmental genes. Nephron Physiol 103, p139-p148.
    • (2006) Nephron Physiol , vol.103 , pp. p139-p148
    • Roxburgh, S.A.1    Murphy, M.2    Pollock, C.A.3    Brazil, D.P.4
  • 47
    • 84901921079 scopus 로고    scopus 로고
    • Pro-resolving lipid mediators are leads for resolution physiology
    • Serhan CN (2014). Pro-resolving lipid mediators are leads for resolution physiology. Nature 510, 92-101.
    • (2014) Nature , vol.510 , pp. 92-101
    • Serhan, C.N.1
  • 48
    • 0029924637 scopus 로고    scopus 로고
    • Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice
    • Sharma K, Jin Y, Guo J & Ziyadeh FN (1996). Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes 45, 522-530.
    • (1996) Diabetes , vol.45 , pp. 522-530
    • Sharma, K.1    Jin, Y.2    Guo, J.3    Ziyadeh, F.N.4
  • 50
    • 79955771730 scopus 로고    scopus 로고
    • The proximal tubule in the pathophysiology of the diabetic kidney
    • Vallon V (2011). The proximal tubule in the pathophysiology of the diabetic kidney. Am J Physiol Regul Integr Comp Physiol 300, R1009-R1022.
    • (2011) Am J Physiol Regul Integr Comp Physiol , vol.300 , pp. R1009-R1022
    • Vallon, V.1
  • 52
    • 77952548279 scopus 로고    scopus 로고
    • Extracellular BMP-antagonist regulation in development and disease: tied up in knots
    • Walsh DW, Godson C, Brazil DP & Martin F (2010). Extracellular BMP-antagonist regulation in development and disease: tied up in knots. Trends Cell Biol 20, 244-256.
    • (2010) Trends Cell Biol , vol.20 , pp. 244-256
    • Walsh, D.W.1    Godson, C.2    Brazil, D.P.3    Martin, F.4
  • 53
    • 84895900338 scopus 로고    scopus 로고
    • Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b
    • Wang B, Jha JC, Hagiwara S, McClelland AD, Jandeleit-Dahm K, Thomas MC, Cooper ME & Kantharidis P (2014). Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b. Kidney Int 85, 352-361.
    • (2014) Kidney Int , vol.85 , pp. 352-361
    • Wang, B.1    Jha, J.C.2    Hagiwara, S.3    McClelland, A.D.4    Jandeleit-Dahm, K.5    Thomas, M.C.6    Cooper, M.E.7    Kantharidis, P.8
  • 54
    • 77953900264 scopus 로고    scopus 로고
    • Macrophages in renal development, injury, and repair
    • Williams TM, Little MH & Ricardo SD (2010). Macrophages in renal development, injury, and repair. Semin Nephrol 30, 255-267.
    • (2010) Semin Nephrol , vol.30 , pp. 255-267
    • Williams, T.M.1    Little, M.H.2    Ricardo, S.D.3
  • 55
    • 0038717407 scopus 로고    scopus 로고
    • BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
    • Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F & Kalluri R (2003). BMP-7 counteracts TGF-β1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 9, 964-968.
    • (2003) Nat Med , vol.9 , pp. 964-968
    • Zeisberg, M.1    Hanai, J.2    Sugimoto, H.3    Mammoto, T.4    Charytan, D.5    Strutz, F.6    Kalluri, R.7
  • 56
    • 77955411901 scopus 로고    scopus 로고
    • In vivo delivery of Gremlin siRNA plasmid reveals therapeutic potential against diabetic nephropathy by recovering bone morphogenetic protein-7
    • Zhang Q, Shi Y, Wada J, Malakauskas SM, Liu M, Ren Y, Du C, Duan H, Li Y, Li Y & Zhang Y (2010). In vivo delivery of Gremlin siRNA plasmid reveals therapeutic potential against diabetic nephropathy by recovering bone morphogenetic protein-7. PLoS One 5, e11709.
    • (2010) PLoS One , vol.5 , pp. e11709
    • Zhang, Q.1    Shi, Y.2    Wada, J.3    Malakauskas, S.M.4    Liu, M.5    Ren, Y.6    Du, C.7    Duan, H.8    Li, Y.9    Li, Y.10    Zhang, Y.11
  • 57
    • 0028790786 scopus 로고
    • Role of protein kinase C and cyclic AMP/protein kinase A in high glucose-stimulated transcriptional activation of collagen α1 (IV) in glomerular mesangial cells
    • Ziyadeh FN, Fumo P, Rodenberger CH, Kuncio GS & Neilson EG (1995). Role of protein kinase C and cyclic AMP/protein kinase A in high glucose-stimulated transcriptional activation of collagen α1 (IV) in glomerular mesangial cells. J Diabetes Complications 9, 255-261.
    • (1995) J Diabetes Complications , vol.9 , pp. 255-261
    • Ziyadeh, F.N.1    Fumo, P.2    Rodenberger, C.H.3    Kuncio, G.S.4    Neilson, E.G.5
  • 58
    • 0028218461 scopus 로고
    • Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta
    • Ziyadeh FN, Sharma K, Ericksen M & Wolf G (1994). Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta. J Clin Invest 93, 536-542.
    • (1994) J Clin Invest , vol.93 , pp. 536-542
    • Ziyadeh, F.N.1    Sharma, K.2    Ericksen, M.3    Wolf, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.