IHG-1 must be localised to mitochondria to decrease Smad7 expression and amplify TGF-β1-induced fibrotic responses

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1833, Issue 8, 2013, Pages 1969-1978

  Corcoran, James B ^a   McCarthy, Sarah ^a   Griffin, Brenda ^a   Gaffney, Andrew ^a   Bhreathnach, Una ^a   Börgeson, Emma ^a   Hickey, Fionnuala B ^a   Docherty, Neil G ^b   Higgins, Debra F ^a   Furlong, Fiona ^a,c   Martin, Finian ^a   Godson, Catherine ^a   Murphy, Madeline ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b TRINITY COLLEGE DUBLIN   (Ireland)

^c QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

IHG 1; Mitochondria; Smad7; TGF 1

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; FIBRONECTIN; INDUCED IN HIGH GLUCOSE 1 PROTEIN; JAGGED1; MITOCHONDRIAL PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; FIBROSIS; GENE AMPLIFICATION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; KIDNEY EPITHELIUM; KIDNEY PROXIMAL TUBULE; MITOCHONDRIAL TARGETING SIGNAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

AMINO ACID SEQUENCE; CALCIUM-BINDING PROTEINS; CELL LINE; CONNECTIVE TISSUE GROWTH FACTOR; EPITHELIAL CELLS; FIBRONECTINS; FIBROSIS; HEK293 CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; MEMBRANE PROTEINS; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEINS; SIGNAL TRANSDUCTION; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84877812701     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2013.03.027     Document Type: Article

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