-
1
-
-
0032737294
-
End-stage renal failure in type 2 diabetes: A medical catastrophe of worldwide dimensions
-
Ritz E, Rychlik I, Locatelli F, Halimi S. End-stage renal failure in type 2 diabetes: a medical catastrophe of worldwide dimensions. Am J Kidney Dis 1999;34:795-808
-
(1999)
Am J Kidney Dis
, vol.34
, pp. 795-808
-
-
Ritz, E.1
Rychlik, I.2
Locatelli, F.3
Halimi, S.4
-
2
-
-
34047248203
-
AGE, RAGE, and ROS in diabetic nephropathy
-
Tan AL, Forbes JM, Cooper ME. AGE, RAGE, and ROS in diabetic nephropathy. Semin Nephrol 2007;27:130-143
-
(2007)
Semin Nephrol
, vol.27
, pp. 130-143
-
-
Tan, A.L.1
Forbes, J.M.2
Cooper, M.E.3
-
3
-
-
0036387022
-
Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-beta-induced fibronectin in mesangial cells
-
Isono M, Chen S, Hong SW, Iglesias-de la Cruz MC, Ziyadeh FN. Smad pathway is activated in the diabetic mouse kidney and Smad3 mediates TGF-beta-induced fibronectin in mesangial cells. Biochem Biophys Res Commun 2002;296:1356-1365
-
(2002)
Biochem Biophys Res Commun
, vol.296
, pp. 1356-1365
-
-
Isono, M.1
Chen, S.2
Hong, S.W.3
Iglesias-de la Cruz, M.C.4
Ziyadeh, F.N.5
-
4
-
-
49949114895
-
Protein kinase B/Akt activity is involved in renal TGF-β1-driven epithelial-mesenchymal transition in vitro and in vivo
-
Kattla JJ, Carew RM, Heljic M, Godson C, Brazil DP. Protein kinase B/Akt activity is involved in renal TGF-β1-driven epithelial-mesenchymal transition in vitro and in vivo. Am J Physiol Renal Physiol 2008;295:F215-F225
-
(2008)
Am J Physiol Renal Physiol
, vol.295
-
-
Kattla, J.J.1
Carew, R.M.2
Heljic, M.3
Godson, C.4
Brazil, D.P.5
-
5
-
-
19944396117
-
Involvement of extracellular signal-regulated kinase and p38 in human diabetic nephropathy
-
Sakai N, Wada T, Furuichi K, Iwata Y, Yoshimoto K, Kitagawa K, Kokubo S, Kobayashi M, Hara A, Yamahana J, Okumura T, Takasawa K, Takeda S, Yoshimura M, Kida H, Yokoyama H. Involvement of extracellular signal-regulated kinase and p38 in human diabetic nephropathy. Am J Kidney Dis 2005;45:54-65
-
(2005)
Am J Kidney Dis
, vol.45
, pp. 54-65
-
-
Sakai, N.1
Wada, T.2
Furuichi, K.3
Iwata, Y.4
Yoshimoto, K.5
Kitagawa, K.6
Kokubo, S.7
Kobayashi, M.8
Hara, A.9
Yamahana, J.10
Okumura, T.11
Takasawa, K.12
Takeda, S.13
Yoshimura, M.14
Kida, H.15
Yokoyama, H.16
-
6
-
-
0032039482
-
The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities
-
Hsu DR, Economides AN, Wang X, Eimon PM, Harland RM. The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities. Mol Cell 1998;1:673-683
-
(1998)
Mol Cell
, vol.1
, pp. 673-683
-
-
Hsu, D.R.1
Economides, A.N.2
Wang, X.3
Eimon, P.M.4
Harland, R.M.5
-
7
-
-
0034708483
-
Biosynthesis, post-translation modification, and functional characterization of Drm/Gremlin
-
Topol LZ, Bardot B, Zhang Q, Resau J, Huillard E, Marx M, Calothy G, Blair DG. Biosynthesis, post-translation modification, and functional characterization of Drm/Gremlin. J Biol Chem 2000;275:8785-8793
-
(2000)
J Biol Chem
, vol.275
, pp. 8785-8793
-
-
Topol, L.Z.1
Bardot, B.2
Zhang, Q.3
Resau, J.4
Huillard, E.5
Marx, M.6
Calothy, G.7
Blair, D.G.8
-
8
-
-
0033402727
-
The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb
-
Merino R, Rodriguez-Leon J, Macias D, Ganan Y, Economides AN, Hurle JM. The BMP antagonist Gremlin regulates outgrowth, chondrogenesis and programmed cell death in the developing limb. Development 1999;126:5515-5522
-
(1999)
Development
, vol.126
, pp. 5515-5522
-
-
Merino, R.1
Rodriguez-Leon, J.2
Macias, D.3
Ganan, Y.4
Economides, A.N.5
Hurle, J.M.6
-
9
-
-
34447550603
-
Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis
-
Michos O, Goncalves A, Lopez-Rios J, Tiecke E, Naillat F, Beier K, Galli A, Vainio S, Zeller R. Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis. Development 2007;134:2397-2405
-
(2007)
Development
, vol.134
, pp. 2397-2405
-
-
Michos, O.1
Goncalves, A.2
Lopez-Rios, J.3
Tiecke, E.4
Naillat, F.5
Beier, K.6
Galli, A.7
Vainio, S.8
Zeller, R.9
-
10
-
-
0037743636
-
Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning
-
Khokha MK, Hsu D, Brunet LJ, Dionne MS, Harland RM. Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning. Nat Genet 2003;34:303-307
-
(2003)
Nat Genet
, vol.34
, pp. 303-307
-
-
Khokha, M.K.1
Hsu, D.2
Brunet, L.J.3
Dionne, M.S.4
Harland, R.M.5
-
11
-
-
4243180526
-
Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis
-
Michos O, Panman L, Vintersten K, Beier K, Zeller R, Zuniga A. Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis. Development 2004;131:3401-3410
-
(2004)
Development
, vol.131
, pp. 3401-3410
-
-
Michos, O.1
Panman, L.2
Vintersten, K.3
Beier, K.4
Zeller, R.5
Zuniga, A.6
-
12
-
-
35748953461
-
Conditional deletion of gremlin causes a transient increase in bone formation and bone mass
-
Gazzerro E, Smerdel-Ramoya A, Zanotti S, Stadmeyer L, Durant D, Economides AN, Canalis E. Conditional deletion of gremlin causes a transient increase in bone formation and bone mass. J Biol Chem 2007;282:31549-31557
-
(2007)
J Biol Chem
, vol.282
, pp. 31549-31557
-
-
Gazzerro, E.1
Smerdel-Ramoya, A.2
Zanotti, S.3
Stadmeyer, L.4
Durant, D.5
Economides, A.N.6
Canalis, E.7
-
13
-
-
12344262661
-
Skeletal overexpression of gremlin impairs bone formation and causes osteopenia
-
Gazzerro E, Pereira RC, Jorgetti V, Olson S, Economides AN, Canalis E. Skeletal overexpression of gremlin impairs bone formation and causes osteopenia. Endocrinology 2005;146:655-665
-
(2005)
Endocrinology
, vol.146
, pp. 655-665
-
-
Gazzerro, E.1
Pereira, R.C.2
Jorgetti, V.3
Olson, S.4
Economides, A.N.5
Canalis, E.6
-
14
-
-
52149085463
-
Lung-selective gene responses to alveolar hypoxia: Potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension
-
Costello CM, Howell K, Cahill E, McBryan J, Konigshoff M, Eickelberg O, Gaine S, Martin F, McLoughlin P. Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2008;295:L272-L284
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
Costello, C.M.1
Howell, K.2
Cahill, E.3
McBryan, J.4
Konigshoff, M.5
Eickelberg, O.6
Gaine, S.7
Martin, F.8
McLoughlin, P.9
-
15
-
-
33847402760
-
Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor
-
Stabile H, Mitola S, Moroni E, Belleri M, Nicoli S, Coltrini D, Peri F, Pessi A, Orsatti L, Talamo F, Castronovo V, Waltregny D, Cotelli F, Ribatti D, Presta M. Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factor. Blood 2007;109:1834-1840
-
(2007)
Blood
, vol.109
, pp. 1834-1840
-
-
Stabile, H.1
Mitola, S.2
Moroni, E.3
Belleri, M.4
Nicoli, S.5
Coltrini, D.6
Peri, F.7
Pessi, A.8
Orsatti, L.9
Talamo, F.10
Castronovo, V.11
Waltregny, D.12
Cotelli, F.13
Ribatti, D.14
Presta, M.15
-
16
-
-
0033605162
-
Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells
-
Murphy M, Godson C, Cannon S, Kato S, Mackenzie HS, Martin F, Brady HR. Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells. J Biol Chem 1999;274:5830-5834
-
(1999)
J Biol Chem
, vol.274
, pp. 5830-5834
-
-
Murphy, M.1
Godson, C.2
Cannon, S.3
Kato, S.4
Mackenzie, H.S.5
Martin, F.6
Brady, H.R.7
-
17
-
-
0034616419
-
IHG-2, a mesangial cell gene induced by high glucose, is human gremlin: Regulation by extracellular glucose concentration, cyclic mechanical strain, and transforming growth factor-beta1
-
McMahon R, Murphy M, Clarkson M, Taal M, Mackenzie HS, Godson C, Martin F, Brady HR. IHG-2, a mesangial cell gene induced by high glucose, is human gremlin: regulation by extracellular glucose concentration, cyclic mechanical strain, and transforming growth factor-beta1. J Biol Chem 2000;275:9901-9904
-
(2000)
J Biol Chem
, vol.275
, pp. 9901-9904
-
-
McMahon, R.1
Murphy, M.2
Clarkson, M.3
Taal, M.4
Mackenzie, H.S.5
Godson, C.6
Martin, F.7
Brady, H.R.8
-
18
-
-
0042329460
-
Gremlin - a putative pathogenic player in progressive renal disease
-
Dolan V, Murphy M, Alarcon P, Brady HR, Hensey C. Gremlin - a putative pathogenic player in progressive renal disease. Expert Opin Ther Targets 2003;7:523-526
-
(2003)
Expert Opin Ther Targets
, vol.7
, pp. 523-526
-
-
Dolan, V.1
Murphy, M.2
Alarcon, P.3
Brady, H.R.4
Hensey, C.5
-
19
-
-
20444364531
-
Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy
-
Dolan V, Murphy M, Sadlier D, Lappin D, Doran P, Godson C, Martin F, O'Meara Y, Schmid H, Henger A, Kretzler M, Droguett A, Mezzano S, Brady HR. Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy. Am J Kidney Dis 2005;45:1034-1039
-
(2005)
Am J Kidney Dis
, vol.45
, pp. 1034-1039
-
-
Dolan, V.1
Murphy, M.2
Sadlier, D.3
Lappin, D.4
Doran, P.5
Godson, C.6
Martin, F.7
O'Meara, Y.8
Schmid, H.9
Henger, A.10
Kretzler, M.11
Droguett, A.12
Mezzano, S.13
Brady, H.R.14
-
20
-
-
39149086711
-
Co-regulation of Gremlin and Notch signalling in diabetic nephropathy
-
Walsh DW, Roxburgh SA, McGettigan P, Berthier CC, Higgins DG, Kretzler M, Cohen CD, Mezzano S, Brazil DP, Martin F. Co-regulation of Gremlin and Notch signalling in diabetic nephropathy. Biochim Biophys Acta 2008;1782:10-21
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 10-21
-
-
Walsh, D.W.1
Roxburgh, S.A.2
McGettigan, P.3
Berthier, C.C.4
Higgins, D.G.5
Kretzler, M.6
Cohen, C.D.7
Mezzano, S.8
Brazil, D.P.9
Martin, F.10
-
21
-
-
34547851691
-
Expression of gremlin, a bone morphogenetic protein antagonist, in glomerular crescents of pauciimmune glomerulonephritis
-
Mezzano S, Droguett A, Burgos ME, Aros C, Ardiles L, Flores C, Carpio D, Carvajal G, Ruiz-Ortega M, Egido J. Expression of gremlin, a bone morphogenetic protein antagonist, in glomerular crescents of pauciimmune glomerulonephritis. Nephrol Dial Transplant 2007;22:1882-1890
-
(2007)
Nephrol Dial Transplant
, vol.22
, pp. 1882-1890
-
-
Mezzano, S.1
Droguett, A.2
Burgos, M.E.3
Aros, C.4
Ardiles, L.5
Flores, C.6
Carpio, D.7
Carvajal, G.8
Ruiz-Ortega, M.9
Egido, J.10
-
22
-
-
42949143822
-
Gremlin: A novel mediator of epithelial mesenchymal transition and fibrosis in chronic allograft nephropathy
-
Carvajal G, Droguett A, Burgos ME, Aros C, Ardiles L, Flores C, Carpio D, Ruiz-Ortega M, Egido J, Mezzano S. Gremlin: a novel mediator of epithelial mesenchymal transition and fibrosis in chronic allograft nephropathy. Transplant Proc 2008;40:734-739
-
(2008)
Transplant Proc
, vol.40
, pp. 734-739
-
-
Carvajal, G.1
Droguett, A.2
Burgos, M.E.3
Aros, C.4
Ardiles, L.5
Flores, C.6
Carpio, D.7
Ruiz-Ortega, M.8
Egido, J.9
Mezzano, S.10
-
23
-
-
33745435247
-
Recapitulation of embryological programmes in renal fibrosis - the importance of epithelial cell plasticity and developmental genes
-
Roxburgh SA, Murphy M, Pollock CA, Brazil DP. Recapitulation of embryological programmes in renal fibrosis - the importance of epithelial cell plasticity and developmental genes. Nephron Physiol 2006;103:139-148
-
(2006)
Nephron Physiol
, vol.103
, pp. 139-148
-
-
Roxburgh, S.A.1
Murphy, M.2
Pollock, C.A.3
Brazil, D.P.4
-
24
-
-
55749104230
-
CTGF Inhibits BMP-7 Signaling in diabetic nephropathy
-
Nguyen TQ, Roestenberg P, van Nieuwenhoven FA, Bovenschen N, Li Z, Xu L, Oliver N, Aten J, Joles JA, Vial C, Brandan E, Lyons KM, Goldschmeding R. CTGF Inhibits BMP-7 Signaling in diabetic nephropathy. J Am Soc Nephrol 2008;19:2098-2107
-
(2008)
J Am Soc Nephrol
, vol.19
, pp. 2098-2107
-
-
Nguyen, T.Q.1
Roestenberg, P.2
van Nieuwenhoven, F.A.3
Bovenschen, N.4
Li, Z.5
Xu, L.6
Oliver, N.7
Aten, J.8
Joles, J.A.9
Vial, C.10
Brandan, E.11
Lyons, K.M.12
Goldschmeding, R.13
-
25
-
-
33644802764
-
Impact of genetic background on nephropathy in diabetic mice
-
Gurley SB, Clare SE, Snow KP, Hu A, Meyer TW, Coffman TM. Impact of genetic background on nephropathy in diabetic mice. Am J Physiol Renal Physiol 2006;290:F214-F222
-
(2006)
Am J Physiol Renal Physiol
, vol.290
-
-
Gurley, S.B.1
Clare, S.E.2
Snow, K.P.3
Hu, A.4
Meyer, T.W.5
Coffman, T.M.6
-
26
-
-
0036385254
-
Gremlin: An example of the re-emergence of developmental programmes in diabetic nephropathy
-
Lappin DW, McMahon R, Murphy M, Brady HR. Gremlin: an example of the re-emergence of developmental programmes in diabetic nephropathy. Nephrol Dial Transplant 2002;17 (Suppl. 9):65-67
-
(2002)
Nephrol Dial Transplant
, vol.17
, Issue.SUPPL. 9
, pp. 65-67
-
-
Lappin, D.W.1
McMahon, R.2
Murphy, M.3
Brady, H.R.4
-
27
-
-
67650243674
-
The effect of alleic deletion of Gremlin on vascular complications associated with a mouse model of type 1 diabetic nephropathy
-
Curran SP, Watson AJ, Brazil DP: The effect of alleic deletion of Gremlin on vascular complications associated with a mouse model of type 1 diabetic nephropathy. J Am Soc Nephrol 2008;19:411A
-
(2008)
J Am Soc Nephrol
, vol.19
-
-
Curran, S.P.1
Watson, A.J.2
Brazil, D.P.3
-
28
-
-
0034758712
-
Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy
-
Wang SN, Lapage J, Hirschberg R. Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy. J Am Soc Nephrol 2001;12:2392-2399
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 2392-2399
-
-
Wang, S.N.1
Lapage, J.2
Hirschberg, R.3
-
29
-
-
33748062324
-
Renal bone morphogenetic protein-7 protects against diabetic nephropathy
-
Wang S, de Caestecker M, Kopp J, Mitu G, Lapage J, Hirschberg R. Renal bone morphogenetic protein-7 protects against diabetic nephropathy. J Am Soc Nephrol 2006;17:2504-2512
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 2504-2512
-
-
Wang, S.1
de Caestecker, M.2
Kopp, J.3
Mitu, G.4
Lapage, J.5
Hirschberg, R.6
-
30
-
-
0242582117
-
Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models
-
Zeisberg M, Bottiglio C, Kumar N, Maeshima Y, Strutz F, Muller GA, Kalluri R. Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. Am J Physiol Renal Physiol 2003;285:F1060-1067
-
(2003)
Am J Physiol Renal Physiol
, vol.285
-
-
Zeisberg, M.1
Bottiglio, C.2
Kumar, N.3
Maeshima, Y.4
Strutz, F.5
Muller, G.A.6
Kalluri, R.7
-
31
-
-
21644463253
-
Heterozygous mice for TGF-βIIR gene are resistant to the progression of streptozotocin-induced diabetic nephropathy
-
Kim HW, Kim BC, Song CY, Kim JH, Hong HK, Lee HS. Heterozygous mice for TGF-βIIR gene are resistant to the progression of streptozotocin-induced diabetic nephropathy. Kidney Int 2004;66:1859-1865
-
(2004)
Kidney Int
, vol.66
, pp. 1859-1865
-
-
Kim, H.W.1
Kim, B.C.2
Song, C.Y.3
Kim, J.H.4
Hong, H.K.5
Lee, H.S.6
|