Effects of oils rich in linoleic and α-linolenic acids on fatty acid profile and gene expression in goat meat

Nutrients

Volumn 6, Issue 9, 2014, Pages 3913-3928

  Ebrahimi, Mahdi ^a   Rajion, Mohamed Ali ^a   Goh, Yong Meng ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Flaxseed oil; Gene expression; Goat meat; Lipogenic genes; Omega 3 fatty acid

Indexed keywords

ACYL COENZYME A DESATURASE; ARACHIDONIC ACID; LINOLEIC ACID; LINSEED OIL; MONOUNSATURATED FATTY ACID; OMEGA 3 FATTY ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; SUNFLOWER OIL; CONJUGATED LINOLEIC ACID; FAT INTAKE; LINOLENIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; VEGETABLE OIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CONTROLLED STUDY; DIET; GENE EXPRESSION; GOAT; LIPID COMPOSITION; MALE; MEAT; NONHUMAN; NUTRITIONAL VALUE; RANDOMIZED CONTROLLED TRIAL; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; RNA EXTRACTION; RNA PURIFICATION; SEMITENDINOUS MUSCLE; ANALYSIS; ANIMAL; ANIMAL FOOD; CHEMISTRY; DRUG EFFECTS; FAT INTAKE; GENETICS; HUMAN; LIPID METABOLISM; METABOLISM; PHARMACOLOGY; SKELETAL MUSCLE; UPREGULATION; VETERINARY;

CAPRA HIRCUS;

ALPHA-LINOLENIC ACID; ANIMAL FEED; ANIMALS; ARACHIDONIC ACID; DIET; DIETARY FATS; GENE EXPRESSION; GOATS; HUMANS; LINOLEIC ACID; LINOLEIC ACIDS, CONJUGATED; LINSEED OIL; LIPID METABOLISM; MEAT; MUSCLE, SKELETAL; PLANT OILS; PPAR ALPHA; PPAR GAMMA; STEAROYL-COA DESATURASE; UP-REGULATION;

EID: 84908134182     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu6093913     Document Type: Article

References (61)

1. Ng, T.K.W. Towards improved fat intake and nutrition for Malaysians. Malays. J. Nutr. 1995, 1, 21-30.
2. Siri-Tarino, P.W.; Sun, Q.; Hu, F.B.; Krauss, R.M. Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. Am. J. Clin. Nutr. 2010, 91, 535-546.
3. Wahle, K.W.J.; Heys, S.D.; Rotondo, D. Conjugated linoleic acids: Are they beneficial or detrimental to health? Prog. Lipid Res. 2004, 43, 553-587.
4. Cutrignelli, M.I.; Calabrò, S.; Bovera, F.; Tudisco, R.; D'Urso, S.; Marchiello, M.; Piccolo, V.; Infascelli, F. Effects of two protein sources and energy level of diet on the performance of young Marchigiana bulls. 2. Meat quality. Ital. J. Anim. Sci. 2010, 7, 271-286.
5. De la Vega, F.; Guzmán, J.L.; Delgado-Pertíñez, M.; Zarazaga, L.A.; Argüello, A. Fatty acid composition of muscle and adipose tissues of organic and conventional Blanca Andaluza suckling kids. Span. J. Agric. Res. 2013, 11, 770-779.
6. Simopoulos, A.P. Omega-3 fatty acids in inflammation and autoimmune diseases. J. Am. Coll. Nutr. 2002, 21, 495-505.
7. Simopoulos, A.P.; Leaf, A.; Salem, N., Jr. Essentiality of and recommended dietary intakes for omega-6 and omega-3 fatty acids. Ann. Nutr. Metab. 1999, 43, 127-130.
8. Givens, D.I.; Kliem, K.E.; Gibbs, R.A. The role of meat as a source of n-3 polyunsaturated fatty acids in the human diet. Meat Sci. 2006, 74, 209-218.
9. Wood, J.D.; Enser, M. Factors Influencing Fatty Acids in Meat and the Role of Antioxidants in Improving Meat Quality. Br. J. Nutr. 1997, 78, S49-S60.
10. Deckelbaum, R.J.; Torrejon, C. The omega-3 fatty acid nutritional landscape: Health benefits and sources. J. Nutr. 2012, 142, 587S-591S.
11. Givens, D.I.; Gibbs, R.A. Current intakes of EPA and DHA in European populations and the potential of animal-derived foods to increase them. Proc. Nutr. Soc. 2008, 67, 273-280.
12. Tudisco, R.; Cutrignelli, M.I.; Calabrò, S.; Piccolo, G.; Bovera, F.; Guglielmelli, A.; Moniello, G.; Infascelli, F. Influence of organic systems on milk fatty acid profile and CLA in goats. Small Rumin. Res. 2010, 88, 151-155.
13. Xu, J.; Gao, H.; Song, L.; Yang, W.; Chen, C.; Deng, Q.; Huang, Q.; Yang, J.; Huang, F. Flaxseed oil and α-lipoic acid combination ameliorates hepatic oxidative stress and lipid accumulation in comparison to lard. Lipids Health Dis. 2013, 12, 58.
14. Legrand, P.; Schmitt, B.; Mourot, J.; Catheline, D.; Chesneau, G.; Mireaux, M.; Kerhoas, N.; Weill, P. The consumption of food products from linseed-fed animals maintains erythrocyte omega-3 fatty acids in obese humans. Lipids 2010, 45, 11-19.
15. Park, Y. Conjugated linoleic acid (CLA): Good or bad trans fat? J. Food Compos. Anal. 2009, 22, S4-S12.
16. Nassu, R.T.; Dugan, M.E.R.; He, M.L.; McAllister, T.A.; Aalhus, J.L.; Aldai, N.; Kramer, J.K.G. The effects of feeding flaxseed to beef cows given forage based diets on fatty acids of longissimus thoracis muscle and backfat. Meat Sci. 2011, 89, 469-477.
17. Göttlicher, M.; Widmark, E.; Li, Q.; Gustafsson, J.A. Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor. Proc. Natl. Acad. Sci. USA 1992, 89, 4653-4657.
18. Issemann, I.; Green, S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 1990, 347, 645-650.
19. Hajjar, T.; Meng, G.; Rajion, M.; Vidyadaran, S.; Othman, F.; Farjam, A.; Li, T.; Ebrahimi, M. Omega 3 polyunsaturated fatty acid improves spatial learning and hippocampal Peroxisome Proliferator Activated Receptors (PPARα and PPARγ) gene expression in rats. BMC Neuroscience 2012, 13, 109.
20. Simopoulos, A.P. Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: Nutritional implications for chronic diseases. Biomed. Pharmacother. 2006, 60, 502-507.
21. Igarashi, M.; Ma, K.; Chang, L.; Bell, J.M.; Rapoport, S.I. Dietary n-3 PUFA deprivation for 15 weeks upregulates elongase and desaturase expression in rat liver but not brain. J. Lipid Res. 2007, 48, 2463-2470.
22. Graugnard, D.; Piantoni, P.; Bionaz, M.; Berger, L.; Faulkner, D.; Loor, J. Adipogenic and energy metabolism gene networks in longissimus lumborum during rapid post-weaning growth in Angus and Angus × Simmental cattle fed high-starch or low-starch diets. BMC Genomics 2009, 10, 142.
23. Waters, S.M.; Kelly, J.P.; O'Boyle, P.; Moloney, A.P.; Kenny, D.A. Effect of level and duration of dietary n-3 polyunsaturated fatty acid supplementation on the transcriptional regulation of Δ9-desaturase in muscle of beef cattle. J. Anim. Sci. 2009, 87, 244-252.
24. Ntambi, J.M. Regulation of stearoyl-CoA desaturase by polyunsaturated fatty acids and cholesterol. J. Lipid Res. 1999, 40, 1549-1558.
25. NRC. Nutrient Requirements of Small Ruminant, 6th ed.; National Academy Press: Washington, DC, USA, 2007; p. 384.
26. AOAC. Official Methods of Analysis; 15th ed.; Herlick, K., Ed.; Association of Official Analytical Chemists: Arlington, VA, USA, 1990; p. 1230.
27. Van Soest, P.; van; Robertson, J.B.; Lewis, B.A. Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. J. Dairy Sci. 1991, 74, 3583-3597.
28. Folch, J.; Lees, M.; Sloane Stanely, G.H. A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 1957, 226, 497-509.
29. Rajion, M.A.; McLean, J.G.; Cahill, R.N. Essential fatty acids in the fetal and newborn lamb. Aust. J. Biol. Sci. 1985, 38, 33-40.
30. Ebrahimi, M.; Rajion, M.A.; Goh, Y.M.; Sazili, A.Q. Impact of different inclusion levels of oil palm (Elaeis guineensis Jacq.) fronds on fatty acid profiles of goat muscles. J. Anim. Physiol. Anim. Nutr. 2012, 96, 962-969.
31. Destaillats, F.; Trottier, J.P.; Galvez, J.M.G.; Angers, P. Analysis of α-Linolenic Acid Biohydrogenation Intermediates in Milk Fat with Emphasis on Conjugated Linolenic Acids. J. Dairy Sci. 2005, 88, 3231-3239.
32. Kramer, J.K.; Hernandez, M.; Cruz-Hernandez, C.; Kraft, J.; Dugan, M.E. Combining results of two GC separations partly achieves determination of all cis and trans 16:1, 18:1, 18:2 and 18:3 except CLA isomers of milk fat as demonstrated using Ag-ion SPE fractionation. Lipids 2008, 43, 259-273.
33. Dervishi, E.; Serrano, C.; Joy, M.; Serrano, M.; Rodellar, C.; Calvo, J.H. The effect of feeding system in the expression of genes related with fat metabolism in semitendinous muscle in sheep. Meat Sci. 2011, 89, 91-97.
34. Ebrahimi, M.; Rajion, M.A.; Goh, Y.M.; Sazili, A.Q.; Schonewille, J.T. Effect of linseed oil dietary supplementation on fatty acid composition and gene expression in adipose tissue of growing goats. BioMed. Res. Int. 2013, 2013, doi:10.1155/2013/194625.
35. Mapiye, C.; Aalhus, J.L.; Turner, T.D.; Rolland, D.C.; Basarab, J.A.; Baron, V.S.; McAllister, T.A.; Block, H.C.; Uttaro, B.; Lopez-Campos, O.; et al. Effects of feeding flaxseed or sunflower-seed in high-forage diets on beef production, quality and fatty acid composition. Meat Sci. 2013, 95, 98-109.
36. Bernard, L.; Bonnet, M.; Leroux, C.; Shingfield, K.J.; Chilliard, Y. Effect of sunflower-seed oil and linseed oil on tissue lipid metabolism, gene expression, and milk fatty acid secretion in alpine goats fed maize silage-based diets. J. Dairy Sci. 2009, 92, 6083-6094.
37. Khas-Erdene, Q.; Wang, J.Q.; Bu, D.P.; Wang, L.; Drackley, J.K.; Liu, Q.S.; Yang, G.; Wei, H.Y.; Zhou, L.Y. Short communication: Responses to increasing amounts of free α-linolenic acid infused into the duodenum of lactating dairy cows. J. Dairy Sci. 2010, 93, 1677-1684.
38. Dewhurst, R.J.; Scollan, N.D.; Lee, M.R.F.; Ougham, H.J.; Humphreys, M.O. Forage breeding and management to increase the beneficial fatty acid content of ruminant products. Proc. Nutr. Soc. 2003, 62, 329-336.
39. Scollan, N.D.; Choi, N.J.; Kurt, E.; Fisher, A.V.; Enser, M.; Wood, J.D. Manipulating the fatty acid composition of muscle and adipose tissue in beef cattle. Br. J. Nutr. 2001, 85, 115-124.
40. Jerónimo, E.; Alves, S.P.; Prates, J.A.M.; Santos-Silva, J.; Bessa, R.J.B. Effect of dietary replacement of sunflower oil with linseed oil on intramuscular fatty acids of lamb meat. Meat Sci. 2009, 83, 499-505.
41. Burdge, G.C.; Calder, P.C. α-Linolenic acid metabolism in adult humans: the effects of gender and age on conversion to longer-chain polyunsaturated fatty acids. Eur. J. Lipid Sci. Technol. 2005, 107, 426-439.
42. Brenner, R.R. Factors influencing fatty acid chain elongation and desaturation. In The Role of Fats in Human Nutrition; Podmore, J., Ed.; Acadamic Press: San Diego, CA, USA, 1989; pp. 45-80.
43. Cooper, S.L.; Sinclair, L.A.; Wilkinson, R.G.; Hallett, K.G.; Enser, M.; Wood, J.D. Manipulation of the n-3 polyunsaturated fatty acid content of muscle and adipose tissue in lambs. J. Anim. Sci. 2004, 82, 1461-1470.
44. Demirel, G.; Wachira, A.M.; Sinclair, L.A.; Wilkinson, R.G.; Wood, J.D.; Enser, M. Effects of dietary n-3 polyunsaturated fatty acids, breed and dietary vitamin E on the fatty acids of lamb muscle, liver and adipose tissue. Br. J. Nutr. 2004, 91, 551-565.
45. Nute, G.R.; Richardson, R.I.; Wood, J.D.; Hughes, S.I.; Wilkinson, R.G.; Cooper, S.L.; Sinclair, L.A. Effect of dietary oil source on the flavour and the color and lipid stability of lamb meat. Meat Sci. 2007, 77, 547-555.
46. Sampath, H.; Ntambi, J.M. Polyunsaturated fatty acid regulation of genes of lipid metabolism. Ann. Rev. Nutr. 2005, 25, 317-340.
47. Bessa, R.J.B.; Alves, S.P.; Jerónimo, E.; Alfaia, C.M.; Prates, J.A.M.; Santos-Silva, J. Effect of lipid supplements on ruminal biohydrogenation intermediates and muscle fatty acids in lambs. Eur. J. Lipid Sci. Technol. 2007, 109, 868-878.
48. Noci, F.; French, P.; Monahan, F.J.; Moloney, A.P. The Fatty Acid Composition of Muscle Fat and Subcutaneous Adipose Tissue of Grazing Heifers Supplemented with Plant Oil-Enriched Concentrates. J. Anim. Sci. 2007, 85, 1062-1073.
49. Vasta, V.; Mele, M.; Serra, A.; Scerra, M.; Luciano, G.; Lanza, M.; Priolo, A. Metabolic fate of fatty acids involved in ruminal biohydrogenation in sheep fed concentrate or herbage with or without tannins. J. Anim. Sci. 2009, 87, 2674-2684.
50. Aharoni, Y.; Orlov, A.; Brosh, A. Effects of high-forage content and oilseed supplementation of fattening diets on conjugated linoleic acid (CLA) and trans fatty acids profiles of beef lipid fractions. Anim. Feed Sci. Technol. 2004, 117, 43-60.
51. Bartoň, L.; Marounek, M.; Kudrna, V.; Bureš, D.; Zahradkova, R. Growth performance and fatty acid profiles of intramuscular and subcutaneous fat from Limousin and Charolais heifers fed extruded linseed. Meat Sci. 2007, 76, 517-523.
52. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids; The National Academies Press: Washington, DC, USA, 2005; p. 423.
53. Raes, K.; de Smet, S.; Demeyer, D. Effect of dietary fatty acids on incorporation of long chain polyunsaturated fatty acids and conjugated linoleic acid in lamb, beef and pork meat: A review. Anim. Feed Sci. Technol. 2004, 113, 199-221.
54. Jaudszus, A.; Jahreis, G.; Schlörmann, W.; Fischer, J.; Kramer, R.; Degen, C.; Rohrer, C.; Roth, A.; Gabriel, H.; Barz, D.; et al. Vaccenic acid-mediated reduction in cytokine production is independent of c9, t11-CLA in human peripheral blood mononuclear cells. Biochim. Biophys. Acta 2012, 1821, 1316-1322.
55. Sofi, F.; Buccioni, A.; Cesari, F.; Gori, A.M.; Minieri, S.; Mannini, L.; Casini, A.; Gensini, G.F.; Abbate, R.; Antongiovanni, M. Effects of a dairy product (pecorino cheese) naturally rich in cis-9, trans-11 conjugated linoleic acid on lipid, inflammatory and haemorheological variables: A dietary intervention study. Nutr. Metab. Cardiovasc. Dis. 2010, 20, 117-124.
56. Dilzer, A.; Park, Y. Implication of conjugated linoleic acid (CLA) in human health. Crit. Rev. Food Sci. Nutr. 2012, 52, 488-513.
57. Pawar, A.; Jump, D.B. Unsaturated fatty acid regulation of peroxisome proliferator-activated receptor alpha activity in rat primary hepatocytes. J. Biol. Chem. 2003, 278, 35931-35939.
58. Al-Hasani, H.; Joost, H.G. Nutrition-/diet-induced changes in gene expression in white adipose tissue. Best Pract. Res. Clin. Endocrinol. Metab. 2005, 19, 589-603.
59. Ntambi, J.M.; Miyazaki, M. Regulation of stearoyl-CoA desaturases and role in metabolism. Prog. Lipid Res. 2004, 43, 91-104.
60. Kim, H.J.; Miyazaki, M.; Ntambi, J.M. Dietary cholesterol opposes PUFA-mediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism. J. Lipid Res. 2002, 43, 1750-1757.
61. Deiuliis, J.; Shin, J.; Murphy, E.; Kronberg, S.L.; Eastridge, M.L.; Suh, Y.; Yoon, J.-T.; Lee, K. Bovine adipose triglyceride lipase is not altered and adipocyte fatty acid-binding protein is increased by dietary flaxseed. Lipids 2010, 45, 963-973.