메뉴 건너뛰기




Volumn 1821, Issue 10, 2012, Pages 1316-1322

Vaccenic acid-mediated reduction in cytokine production is independent of c9,t11-CLA in human peripheral blood mononuclear cells

Author keywords

CLA; Conversion; Cytokine; PBMC; Th cell; Vaccenic acid

Indexed keywords

ACYL COENZYME A DESATURASE; CONJUGATED LINOLEIC ACID; INTERLEUKIN 2; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; VACCENIC ACID;

EID: 84864136495     PISSN: 13881981     EISSN: 18792618     Source Type: Journal    
DOI: 10.1016/j.bbalip.2012.06.010     Document Type: Article
Times cited : (45)

References (52)
  • 1
    • 33747049581 scopus 로고    scopus 로고
    • Plasma phospholipid trans fatty acids, fatal ischemic heart disease, and sudden cardiac death in older adults: The cardiovascular health study
    • DOI 10.1161/CIRCULATIONAHA.106.620336, PII 0000301720060718000008
    • R.N. Lemaitre, I.B. King, D. Mozaffarian, N. Sotoodehnia, T.D. Rea, L.H. Kuller, R.P. Tracy, and D.S. Siscovick Plasma phospholipid trans fatty acids, fatal ischemic heart disease, and sudden cardiac death in older adults: the cardiovascular health study Circulation 114 2006 209 215 (Pubitemid 44297114)
    • (2006) Circulation , vol.114 , Issue.3 , pp. 209-215
    • Lemaitre, R.N.1    King, I.B.2    Mozaffarian, D.3    Sotoodehnia, N.4    Rea, T.D.5    Kuller, L.H.6    Tracy, R.P.7    Siscovick, D.S.8
  • 2
    • 34247117217 scopus 로고    scopus 로고
    • A prospective study of trans fatty acids in erythrocytes and risk of coronary heart disease
    • DOI 10.1161/CIRCULATIONAHA.106.679985
    • Q. Sun, J. Ma, H. Campos, S.E. Hankinson, J.E. Manson, M.J. Stampfer, K.M. Rexrode, W.C. Willett, and F.B. Hu A prospective study of trans fatty acids in erythrocytes and risk of coronary heart disease Circulation 115 2007 1858 1865 (Pubitemid 46598899)
    • (2007) Circulation , vol.115 , Issue.14 , pp. 1858-1865
    • Sun, Q.1    Ma, J.2    Campos, H.3    Hankinson, S.E.4    Manson, J.E.5    Stampfer, M.J.6    Rexrode, K.M.7    Willett, W.C.8    Hu, F.B.9
  • 3
    • 84555203361 scopus 로고    scopus 로고
    • Trans fatty acids induce vascular inflammation and reduce vascular nitric oxide production in endothelial cells
    • N.G. Iwata, M. Pham, N.O. Rizzo, A.M. Cheng, E. Maloney, and F. Kim Trans fatty acids induce vascular inflammation and reduce vascular nitric oxide production in endothelial cells PLoS One 6 2011 e29600
    • (2011) PLoS One , vol.6 , pp. 29600
    • Iwata, N.G.1    Pham, M.2    Rizzo, N.O.3    Cheng, A.M.4    Maloney, E.5    Kim, F.6
  • 4
  • 5
    • 70149109519 scopus 로고    scopus 로고
    • Vaccenic acid favourably alters immune function in obese JCR:LA-cp rats
    • H.J. Blewett, C.A. Gerdung, M.R. Ruth, S.D. Proctor, and C.J. Field Vaccenic acid favourably alters immune function in obese JCR:LA-cp rats Br. J. Nutr. 102 2009 526 536
    • (2009) Br. J. Nutr. , vol.102 , pp. 526-536
    • Blewett, H.J.1    Gerdung, C.A.2    Ruth, M.R.3    Proctor, S.D.4    Field, C.J.5
  • 6
    • 79954621557 scopus 로고    scopus 로고
    • Bovine milk fat enriched in conjugated linoleic and vaccenic acids attenuates allergic dermatitis in mice
    • X. Sun, J. Zhang, A.K. MacGibbon, P. Black, and G.W. Krissansen Bovine milk fat enriched in conjugated linoleic and vaccenic acids attenuates allergic dermatitis in mice Clin. Exp. Allergy 41 2011 729 738
    • (2011) Clin. Exp. Allergy , vol.41 , pp. 729-738
    • Sun, X.1    Zhang, J.2    MacGibbon, A.K.3    Black, P.4    Krissansen, G.W.5
  • 7
    • 32144451380 scopus 로고    scopus 로고
    • Factors affecting conjugated linoleic acid content in milk and meat
    • DOI 10.1080/10408390591034463, PII T5437334220
    • T.R. Dhiman, S.H. Nam, and A.L. Ure Factors affecting conjugated linoleic acid content in milk and meat Crit. Rev. Food Sci. Nutr. 45 2005 463 482 (Pubitemid 43203789)
    • (2005) Critical Reviews in Food Science and Nutrition , vol.45 , Issue.6 , pp. 463-482
    • Dhiman, T.R.1    Nam, S.-H.2    Ure, A.L.3
  • 9
    • 28444498355 scopus 로고    scopus 로고
    • Cis-9,Trans-11-CLA exerts anti-inflammatory effects in human bronchial epithelial cells and eosinophils: Comparison to Trans-10,Cis-12-CLA and to linoleic acid
    • DOI 10.1016/j.bbalip.2005.11.001, PII S1388198105002696
    • A. Jaudszus, M. Foerster, C. Kroegel, I. Wolf, and G. Jahreis Cis-9, trans-11-conjugated linoleic acid exerts anti-inflammatory effects in human bronchial epithelial cells and eosinophils: comparison to trans-10, cis-12-CLA and linoleic acid Biochim. Biophys. Acta 1737 2005 111 118 (Pubitemid 41740705)
    • (2005) Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids , vol.1737 , Issue.2-3 , pp. 111-118
    • Jaudszus, A.1    Foerster, M.2    Kroegel, C.3    Wolf, I.4    Jahreis, G.5
  • 10
    • 46249130552 scopus 로고    scopus 로고
    • Cis-9, trans-11-conjugated linoleic acid inhibits allergic sensitization and airway inflammation via a PPARγ-related mechanism in mice
    • A. Jaudszus, M. Krokowski, P. Möckel, Y. Darcan, A. Avagyan, P. Matricardi, G. Jahreis, and E. Hamelmann Cis-9, trans-11-conjugated linoleic acid inhibits allergic sensitization and airway inflammation via a PPARγ-related mechanism in mice J. Nutr. 138 2008 1336 1342 (Pubitemid 351930999)
    • (2008) Journal of Nutrition , vol.138 , Issue.7 , pp. 1336-1342
    • Jaudszus, A.1    Krokowski, M.2    Mockel, P.3    Darcan, Y.4    Avagyan, A.5    Matricardi, P.6    Jahreis, G.7    Hamelmann, E.8
  • 11
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • B. Desvergne, and W. Wahli Peroxisome proliferator-activated receptors: nuclear control of metabolism Endocr. Rev. 20 1999 649 688 (Pubitemid 30650602)
    • (1999) Endocrine Reviews , vol.20 , Issue.5 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 13
    • 70350133800 scopus 로고    scopus 로고
    • Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease
    • M.G. Belvisi, and J.A. Mitchell Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease Br. J. Pharmacol. 158 2009 994 1003
    • (2009) Br. J. Pharmacol. , vol.158 , pp. 994-1003
    • Belvisi, M.G.1    Mitchell, J.A.2
  • 15
    • 77954977685 scopus 로고    scopus 로고
    • PPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1
    • A. Majdalawieh, and H.S. Ro PPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1 Nucl. Recept. Signal. 8 2010 e004
    • (2010) Nucl. Recept. Signal. , vol.8 , pp. 004
    • Majdalawieh, A.1    Ro, H.S.2
  • 16
    • 0034141545 scopus 로고    scopus 로고
    • The nuclear receptor PPARγ and immunoregulation: PPARγ mediates inhibition of helper T cell responses
    • R. Clark, D. Bishop-Bailey, T. Estrada-Hernandez, T. Hla, L. Puddington, and S. Padula The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses J. Immunol. 164 2000 1364 1371 (Pubitemid 30067250)
    • (2000) Journal of Immunology , vol.164 , Issue.3 , pp. 1364-1371
    • Clark, R.B.1    Bishop-Bailey, D.2    Estrada-Hernandez, T.3    Hla, T.4    Puddington, L.5    Padula, S.J.6
  • 17
  • 19
    • 77955358792 scopus 로고    scopus 로고
    • Losartan inhibits LPS-induced inflammatory signaling through a PPARgamma-dependent mechanism in human THP-1 macrophages
    • J. An, T. Nakajimi, K. Kuba, and A. Kimura Losartan inhibits LPS-induced inflammatory signaling through a PPARgamma-dependent mechanism in human THP-1 macrophages Hypertens. Res. 33 2010 831 835
    • (2010) Hypertens. Res. , vol.33 , pp. 831-835
    • An, J.1    Nakajimi, T.2    Kuba, K.3    Kimura, A.4
  • 20
    • 24144471128 scopus 로고    scopus 로고
    • PPARγ antagonists exacerbate neural antigen-specific Th1 response and experimental allergic encephalomyelitis
    • DOI 10.1016/j.jneuroim.2005.06.026, PII S0165572805002717
    • H.P. Raikwar, G. Muthian, J. Rajasingh, C. Johnson, and J.J. Bright PPARgamma antagonists exacerbate neural antigen-specific Th1 response and experimental allergic encephalomyelitis J. Neuroimmunol. 167 2005 99 107 (Pubitemid 41242292)
    • (2005) Journal of Neuroimmunology , vol.167 , Issue.1-2 , pp. 99-107
    • Raikwar, H.P.1    Muthian, G.2    Rajasingh, J.3    Johnson, C.4    Bright, J.J.5
  • 23
    • 77957302602 scopus 로고    scopus 로고
    • Trans-10, cis-12-CLA-caused lipodystrophy is associated with profound changes of fatty acid profiles of liver, white adipose tissue and erythrocytes in mice: Possible link to tissue-specific alterations of fatty acid desaturation
    • A. Jaudszus, P. Möckel, E. Hamelmann, and G. Jahreis Trans-10, cis-12-CLA-caused lipodystrophy is associated with profound changes of fatty acid profiles of liver, white adipose tissue and erythrocytes in mice: possible link to tissue-specific alterations of fatty acid desaturation Ann. Nutr. Metab. 57 2010 103 111
    • (2010) Ann. Nutr. Metab. , vol.57 , pp. 103-111
    • Jaudszus, A.1    Möckel, P.2    Hamelmann, E.3    Jahreis, G.4
  • 24
    • 79961122450 scopus 로고    scopus 로고
    • Influence of in vitro supplementation with lipids from conventional and Alpine milk on fatty acid distribution and cell growth of HT-29 cells
    • C. Degen, A. Lochner, S. Keller, K. Kuhnt, S. Dänicke, and G. Jahreis Influence of in vitro supplementation with lipids from conventional and Alpine milk on fatty acid distribution and cell growth of HT-29 cells Lipids Health Dis. 10 2011 131
    • (2011) Lipids Health Dis. , vol.10 , pp. 131
    • Degen, C.1    Lochner, A.2    Keller, S.3    Kuhnt, K.4    Dänicke, S.5    Jahreis, G.6
  • 25
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
    • M.W. Pfaffl, G.W. Horgan, and L. Dempfle Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR Nucleic Acids Res. 30 2002 e36
    • (2002) Nucleic Acids Res. , vol.30 , pp. 36
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 26
    • 3142615272 scopus 로고    scopus 로고
    • Validation of housekeeping genes for normalizing RNA expression in real-time PCR
    • K. Dheda, J.F. Huggett, S.A. Bustin, M.A. Johnson, G. Rook, and A. Zumla Validation of housekeeping genes for normalizing RNA expression in real-time PCR Biotechniques 37 2004 112 119 (Pubitemid 38902668)
    • (2004) BioTechniques , vol.37 , Issue.1 , pp. 112-119
    • Dheda, K.1    Huggett, J.F.2    Bustin, S.A.3    Johnson, M.A.4    Rook, G.5    Zumla, A.6
  • 27
    • 84863491204 scopus 로고    scopus 로고
    • Absorption and metabolism of cis-9, trans-11-CLA and of its oxidation product 9,11-furan fatty acid by Caco-2 cells
    • T. Buhrke, R. Merkel, I. Lengler, and A. Lampen Absorption and metabolism of cis-9, trans-11-CLA and of its oxidation product 9,11-furan fatty acid by Caco-2 cells Lipids 47 2012 435 442
    • (2012) Lipids , vol.47 , pp. 435-442
    • Buhrke, T.1    Merkel, R.2    Lengler, I.3    Lampen, A.4
  • 28
    • 0034699514 scopus 로고    scopus 로고
    • Flow cytometric measurement of intracellular cytokines
    • P. Pala, T. Hussell, and P.J. Openshaw Flow cytometric measurement of intracellular cytokines J. Immunol. Methods 243 2000 107 124
    • (2000) J. Immunol. Methods , vol.243 , pp. 107-124
    • Pala, P.1    Hussell, T.2    Openshaw, P.J.3
  • 29
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • T.R. Mosmann, and R.L. Coffman Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties Annu. Rev. Immunol. 7 1989 145 173 (Pubitemid 19138011)
    • (1989) Annual Review of Immunology , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 30
    • 0033050060 scopus 로고    scopus 로고
    • Expression and kinetics of cytokines determined by intracellular staining using flow cytometry
    • DOI 10.1016/S0022-1759(98)00200-2, PII S0022175998002002
    • B. Mascher, P. Schlenke, and M. Seyfarth Expression and kinetics of cytokines determined by intracellular staining using flow cytometry J. Immunol. Methods 223 1999 115 121 (Pubitemid 29096243)
    • (1999) Journal of Immunological Methods , vol.223 , Issue.1 , pp. 115-121
    • Mascher, B.1    Schlenke, P.2    Seyfarth, M.3
  • 31
    • 4744366295 scopus 로고    scopus 로고
    • The anticarcinogenic effect of trans-11 18:1 is dependent on its conversion to cis-9, trans-11 CLA by Δ9-desaturase in rats
    • A.L. Lock, B.A. Corl, D.M. Barbano, D.E. Bauman, and C. Ip The anticarcinogenic effect of trans-11 18:1 is dependent on its conversion to cis-9 trans-11 CLA by delta9-desaturase in rats J. Nutr. 134 2004 2698 2704 (Pubitemid 39315275)
    • (2004) Journal of Nutrition , vol.134 , Issue.10 , pp. 2698-2704
    • Lock, A.L.1    Corl, B.A.2    Barbano, D.M.3    Bauman, D.E.4    Ip, C.5
  • 33
    • 33646440015 scopus 로고    scopus 로고
    • Trans-11-18: 1 is effectively Delta9-desaturated compared with trans-12-18: 1 in humans
    • K. Kuhnt, J. Kraft, P. Moeckel, and G. Jahreis Trans-11-18: 1 is effectively Delta9-desaturated compared with trans-12-18: 1 in humans Br. J. Nutr. 95 2006 752 761
    • (2006) Br. J. Nutr. , vol.95 , pp. 752-761
    • Kuhnt, K.1    Kraft, J.2    Moeckel, P.3    Jahreis, G.4
  • 34
    • 0037227098 scopus 로고    scopus 로고
    • Dietary conjugated linoleic acid decreased cachexia, macrophage tumor necrosis factor-α production, and modifies splenocyte cytokines production
    • M. Yang, and M.E. Cook Dietary conjugated linoleic acid decreased cachexia, macrophage tumor necrosis factor-alpha production, and modifies splenocyte cytokines production Exp. Biol. Med. 228 2003 51 58 (Pubitemid 36077628)
    • (2003) Experimental Biology and Medicine , vol.228 , Issue.1 , pp. 51-58
    • Yang, M.1    Cook, M.E.2
  • 35
    • 26844478237 scopus 로고    scopus 로고
    • Conjugated linoleic acid suppresses NF-κB activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction
    • C.E. Loscher, E. Draper, O. Leavy, D. Kelleher, K.H. Mills, and H.M. Roche Conjugated linoleic acid suppresses NF-kappa B activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction J. Immunol. 175 2005 4990 4998 (Pubitemid 41456381)
    • (2005) Journal of Immunology , vol.175 , Issue.8 , pp. 4990-4998
    • Loscher, C.E.1    Draper, E.2    Leavy, O.3    Kelleher, D.4    Mills, K.H.G.5    Roche, H.M.6
  • 36
    • 33847399236 scopus 로고    scopus 로고
    • Antidiabetic effects of cis-9, trans-11-conjugated linoleic acid may be mediated via anti-inflammatory effects in white adipose tissue
    • DOI 10.2337/db06-0384
    • F. Moloney, S. Toomey, E. Noone, A. Nugent, B. Allan, C.E. Loscher, and H.M. Roche Antidiabetic effects of cis-9, trans-11-conjugated linoleic acid may be mediated via anti-inflammatory effects in white adipose tissue Diabetes 56 2007 574 582 (Pubitemid 46348448)
    • (2007) Diabetes , vol.56 , Issue.3 , pp. 574-582
    • Moloney, F.1    Toomey, S.2    Noone, E.3    Nugent, A.4    Allan, B.5    Loscher, C.E.6    Roche, H.M.7
  • 40
    • 53049096235 scopus 로고    scopus 로고
    • Immunological and metabolic effects of cis-9, trans-11-conjugated linoleic acid in subjects with birch pollen allergy
    • A.M. Turpeinen, N. Ylönen, E. von Willebrand, S. Basu, and A. Aro Immunological and metabolic effects of cis-9, trans-11-conjugated linoleic acid in subjects with birch pollen allergy Br. J. Nutr. 100 2008 112 119
    • (2008) Br. J. Nutr. , vol.100 , pp. 112-119
    • Turpeinen, A.M.1    Ylönen, N.2    Von Willebrand, E.3    Basu, S.4    Aro, A.5
  • 41
    • 0025295658 scopus 로고
    • Fatty acid metabolism in human lymphocytes. II. Activation of fatty acid desaturase-elongase systems during blastic transformation
    • DOI 10.1016/0005-2760(90)90077-B
    • A. Anel, J. Naval, B. González, J. Uriel, and A. Piñeiro Fatty acid metabolism in human lymphocytes. II. Activation of fatty acid desaturase-elongase systems during blasting transformation Biochim. Biophys. Acta 1044 1990 332 339 (Pubitemid 20192408)
    • (1990) Biochimica et Biophysica Acta - Lipids and Lipid Metabolism , vol.1044 , Issue.3 , pp. 332-339
    • Anel, A.1    Naval, J.2    Gonzalez, B.3    Uriel, J.4    Pineiro, A.5
  • 42
    • 34250620932 scopus 로고    scopus 로고
    • Dietary supplementation with trans-11- and trans-12-18 : 1 increases cis-9, trans-11-conjugated linoleic acid in human immune cells, but without effects on biomarkers of immune function and inflammation
    • DOI 10.1017/S0007114507685183, PII S0007114507685183
    • K. Kuhnt, J. Kraft, H. Vogelsang, K. Eder, J. Kratzsch, and G. Jahreis Dietary supplementation with trans-11- and trans-12-18: 1 increases cis-9, trans-11-conjugated linoleic acid in human immune cells, but without effects on biomarkers of immune function and inflammation Br. J. Nutr. 97 2007 1196 1205 (Pubitemid 46927836)
    • (2007) British Journal of Nutrition , vol.97 , Issue.6 , pp. 1196-1205
    • Kuhnt, K.1    Kraft, J.2    Vogelsang, H.3    Eder, K.4    Kratzsch, J.5    Jahreis, G.6
  • 43
    • 53049105127 scopus 로고    scopus 로고
    • Cis-9, trans-11-conjugated linoleic acid but not its precursor trans-vaccenic acid attenuate inflammatory markers in the human colonic epithelial cell line Caco-2
    • C.M. Reynolds, C.E. Loscher, A.P. Moloney, and H.M. Roche Cis-9, trans-11-conjugated linoleic acid but not its precursor trans-vaccenic acid attenuate inflammatory markers in the human colonic epithelial cell line Caco-2 Br. J. Nutr. 100 2008 13 17
    • (2008) Br. J. Nutr. , vol.100 , pp. 13-17
    • Reynolds, C.M.1    Loscher, C.E.2    Moloney, A.P.3    Roche, H.M.4
  • 44
    • 38849151045 scopus 로고    scopus 로고
    • Δ6 desaturase mRNA abundance in HepG2 cells is suppressed by unsaturated fatty acids
    • DOI 10.1007/s11745-007-3122-9
    • P. Portolesi, B.C. Powell, and R.A. Gibson Delta6 desaturase mRNA abundance in HepG2 is suppressed by unsaturated fatty acids Lipids 43 2008 91 95 (Pubitemid 351206959)
    • (2008) Lipids , vol.43 , Issue.1 , pp. 91-95
    • Portolesi, R.1    Powell, B.C.2    Gibson, R.A.3
  • 45
    • 33644622312 scopus 로고    scopus 로고
    • CLA isomers inhibit TNFα-induced eicosanoid release from human vascular smooth muscle cells via a PPARγ ligand-like action
    • DOI 10.1016/j.bbagen.2005.12.002, PII S0304416505003892
    • R. Ringseis, A. Müller, C. Herter, S. Gahler, H. Steinhart, and K. Eder CLA isomers inhibit TNFalpha-induced eicosanoid release from human vascular smooth muscle cells via a PPARgamma ligand-like action Biochim. Biophys. Acta 1760 2006 290 300 (Pubitemid 43320519)
    • (2006) Biochimica et Biophysica Acta - General Subjects , vol.1760 , Issue.2 , pp. 290-300
    • Ringseis, R.1    Muller, A.2    Herter, C.3    Gahler, S.4    Steinhart, H.5    Eder, K.6
  • 46
    • 4143075977 scopus 로고    scopus 로고
    • Capsaicin inhibits the production of tumor necrosis factor α by LPS-stimulated murine macrophages, RAW 264.7: A PPARγ ligand-like action as a novel mechanism
    • DOI 10.1016/j.febslet.2004.06.084, PII S0014579304008464
    • J.Y. Park, T. Kawada, I.S. Han, B.S. Kim, T. Goto, N. Takahashi, T. Fushiki, T. Kurata, and R. Yu Capsaicin inhibits the production of tumor necrosis factor alpha by LPS-stimulated murine macrophages, RAW 264.7: a PPARgamma ligand-like action as a novel mechanism FEBS Lett. 572 2004 266 270 (Pubitemid 39092547)
    • (2004) FEBS Letters , vol.572 , Issue.1-3 , pp. 266-270
    • Park, J.-Y.1    Kawada, T.2    Han, I.-S.3    Kim, B.-S.4    Goto, T.5    Takahashi, N.6    Fushiki, T.7    Kurata, T.8    Yu, R.9
  • 47
    • 0026705751 scopus 로고
    • Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
    • S.A. Kliewer, K. Umesono, D.J. Noonan, R.A. Heyman, and R.M. Evans Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors Nature 358 1992 771 774
    • (1992) Nature , vol.358 , pp. 771-774
    • Kliewer, S.A.1    Umesono, K.2    Noonan, D.J.3    Heyman, R.A.4    Evans, R.M.5
  • 48
    • 0035853840 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/p300
    • K. Subbaramaiah, D.T. Lin, J.C. Hart, and A.J. Dannenberg Peroxisome proliferator-activated receptor-gamma ligands suppress the transcriptional activation of cyclooxygenase-2. Evidence for involvement of activator protein-1 and CREB-binding protein/p300 J. Biol. Chem. 276 2001 12440 12448
    • (2001) J. Biol. Chem. , vol.276 , pp. 12440-12448
    • Subbaramaiah, K.1    Lin, D.T.2    Hart, J.C.3    Dannenberg, A.J.4
  • 49
    • 0034965596 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in inflammation control
    • DOI 10.1677/joe.0.1690453
    • P. Delerive, J.C. Fruchart, and B. Staels Peroxisome proliferator- activated receptors in inflammation control J. Endocrinol. 169 2001 453 459 (Pubitemid 32536978)
    • (2001) Journal of Endocrinology , vol.169 , Issue.3 , pp. 453-459
    • Delerive, P.1    Fruchart, J.-C.2    Staels, B.3
  • 50
    • 0035105403 scopus 로고    scopus 로고
    • Inhibition of the transcription factors AP-1 and NF-κB in CD4 T cells by peroxisome proliferator-activated receptor γ ligands
    • DOI 10.1016/S1567-5769(01)00015-7, PII S1567576901000157
    • P. Wang, P.O. Anderson, S. Chen, K.M. Paulsson, H.O. Sjogren, and S. Li Inhibition of the transcription factors AP-1 and NF-kappaB in CD4 T cells by peroxisome proliferator-activated receptor gamma ligands Int. Immunopharmacol. 1 2001 803 812 (Pubitemid 32206542)
    • (2001) International Immunopharmacology , vol.1 , Issue.4 , pp. 803-812
    • Wang, P.1    Anderson, P.O.2    Chen, S.3    Paulsson, K.M.4    Sjogren, H.-O.5    Li, S.6
  • 51
    • 0142210174 scopus 로고    scopus 로고
    • + T Cells by Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) Ligands: Involvement of Physical Association between PPAR-γ and the Nuclear Factor of Activated T Cells Transcription Factor
    • DOI 10.1124/mol.64.5.1169
    • S.W. Chung, B.Y. Kang, and T.S. Kim Inhibition of interleukin-4 production in CD4 + T cells by peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands: involvement of physical association of between PPAR-gamma and the nuclear factor of activated T cells transcription factor Mol. Pharmacol. 64 2003 1169 1179 (Pubitemid 37310750)
    • (2003) Molecular Pharmacology , vol.64 , Issue.5 , pp. 1169-1179
    • Chung, S.W.1    Kang, B.Y.2    Kim, T.S.3
  • 52
    • 72249116910 scopus 로고    scopus 로고
    • A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4
    • C.M. Reynolds, E. Draper, B. Keogh, A. Rahman, A.P. Moloney, K.H. Mills, C.E. Loscher, and H.M. Roche A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4 J. Nutr. 139 2009 2351 2357
    • (2009) J. Nutr. , vol.139 , pp. 2351-2357
    • Reynolds, C.M.1    Draper, E.2    Keogh, B.3    Rahman, A.4    Moloney, A.P.5    Mills, K.H.6    Loscher, C.E.7    Roche, H.M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.