Hepatic entrapment of esterified cholesterol drives continual expansion of whole body sterol pool in lysosomal acid lipase-deficient mice

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 307, Issue 8, 2014, Pages G836-G847

  Lopez, Adam M ^a   Posey, Kenneth S ^a   Repa, Joyce J ^a,a   Turley, Stephen D ^a   Aqul, Amal ^a   Taylor, Anna M ^a,b   Burns, Dennis K ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Cholesterol synthesis; Esterified cholesterol; Hepatomegaly; Lysosomal storage disease; Sterol balance

Indexed keywords

4 IODO 2,5 DIMETHOXYAMPHETAMINE; ACID LIPASE; CHOLESTEROL ESTER; STEROL; CHOLESTEROL ESTERASE; LYSOSOMAL ACID LIPASE, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE FLOW; CHOLESTEROL ESTER STORAGE DISEASE; CHOLESTEROL LIVER LEVEL; CHOLESTEROL SYNTHESIS; ENZYME DEFICIENCY; FEMALE; LIPID ABSORPTION; LIPID ANALYSIS; LIVER; LUNG; MALE; MOUSE; MOUSE MODEL; NONHUMAN; QUANTITATIVE ANALYSIS; SMALL INTESTINE; SPLEEN; STEROL EXCRETION; STEROL SYNTHESIS; SYSTEMATIC REVIEW; ANIMAL; DEFICIENCY; GENETICS; INTESTINE; INTESTINE ABSORPTION; METABOLISM;

ANIMALS; CHOLESTEROL ESTER STORAGE DISEASE; CHOLESTEROL ESTERS; FEMALE; INTESTINAL ABSORPTION; INTESTINES; LIVER; LUNG; MALE; MICE; SPLEEN; STEROL ESTERASE;

EID: 84908110058     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00243.2014     Document Type: Article

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