-
1
-
-
0042763165
-
Increase in signal-tonoise ratio of > 10,000 times in liquid-state NMR
-
Ardenkjaer-Larsen JH, Fridlund B, Gram A, Hansson G, Hansson L, Lerche MH, Servin R, Thaning M, Golman K. Increase in signal-tonoise ratio of > 10,000 times in liquid-state NMR. Proc Natl Acad Sci USA 100: 10158-10163, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10158-10163
-
-
Ardenkjaer-Larsen, J.H.1
Fridlund, B.2
Gram, A.3
Hansson, G.4
Hansson, L.5
Lerche, M.H.6
Servin, R.7
Thaning, M.8
Golman, K.9
-
2
-
-
79958777022
-
Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: A combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study
-
Atherton HJ, Dodd MS, Heather LC, Schroeder MA, Griffin JL, Radda GK, Clarke K, Tyler DJ. Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study. Circulation 123: 2552-2561, 2011.
-
(2011)
Circulation
, vol.123
, pp. 2552-2561
-
-
Atherton, H.J.1
Dodd, M.S.2
Heather, L.C.3
Schroeder, M.A.4
Griffin, J.L.5
Radda, G.K.6
Clarke, K.7
Tyler, D.J.8
-
3
-
-
79951820751
-
Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS
-
Atherton HJ, Schroeder MA, Dodd MS, Heather LC, Carter EE, Cochlin LE, Nagel S, Sibson NR, Radda GK, Clarke K, Tyler DJ. Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS. NMR Biomed 24: 201-208, 2011.
-
(2011)
NMR Biomed
, vol.24
, pp. 201-208
-
-
Atherton, H.J.1
Schroeder, M.A.2
Dodd, M.S.3
Heather, L.C.4
Carter, E.E.5
Cochlin, L.E.6
Nagel, S.7
Sibson, N.R.8
Radda, G.K.9
Clarke, K.10
Tyler, D.J.11
-
4
-
-
19644362468
-
Glucose-insulinpotassium in cardiac surgery: A meta-analysis
-
Bothe W, Olschewski M, Beyersdorf F, Doenst T. Glucose-insulinpotassium in cardiac surgery: a meta-analysis. Ann Thorac Surg 78: 1650-1657, 2004.
-
(2004)
Ann Thorac Surg
, vol.78
, pp. 1650-1657
-
-
Bothe, W.1
Olschewski, M.2
Beyersdorf, F.3
Doenst, T.4
-
5
-
-
33745105118
-
Anaplerotic molecules: Current and future
-
Brunengraber H, Roe CR. Anaplerotic molecules: current and future. J Inherit Metab Dis 29: 327-331, 2006.
-
(2006)
J Inherit Metab Dis
, vol.29
, pp. 327-331
-
-
Brunengraber, H.1
Roe, C.R.2
-
6
-
-
10644296223
-
Therapeutic effects of l-carnitine and propionyl-l-carnitine on cardiovascular diseases: A review
-
Ferrari R, Merli E, Cicchitelli G, Mele D, Fucili A, Ceconi C. Therapeutic effects of l-carnitine and propionyl-l-carnitine on cardiovascular diseases: a review. Ann N Y Acad Sci 1033: 79-91, 2004.
-
(2004)
Ann N Y Acad Sci
, vol.1033
, pp. 79-91
-
-
Ferrari, R.1
Merli, E.2
Cicchitelli, G.3
Mele, D.4
Fucili, A.5
Ceconi, C.6
-
7
-
-
0013772833
-
Regulation of glucose uptake by muscle. Effects of fatty acids and ketone bodies, and of alloxandiabetes and starvation, on pyruvate metabolism and on lactate-pyruvate and L-glycerol 3-phosphate-dihydroxyacetone phosphate concentration ratios in rat heart and rat diaphragm muscles
-
Garland PB, Newsholme EA, Randle PJ. Regulation of glucose uptake by muscle. Effects of fatty acids and ketone bodies, and of alloxandiabetes and starvation, on pyruvate metabolism and on lactate-pyruvate and L-glycerol 3-phosphate-dihydroxyacetone phosphate concentration ratios in rat heart and rat diaphragm muscles. Biochem J 93: 665-678, 1964.
-
(1964)
Biochem J
, vol.93
, pp. 665-678
-
-
Garland, P.B.1
Newsholme, E.A.2
Randle, P.J.3
-
9
-
-
42549171517
-
13C MRI
-
13C MRI. Magn Reson Med 59: 1005-1013, 2008.
-
(2008)
Magn Reson Med
, vol.59
, pp. 1005-1013
-
-
Golman, K.1
Petersson, J.S.2
Magnusson, P.3
Johansson, E.4
Åkeson, P.5
Chai, C.6
Hansson, G.7
Månsson, S.8
-
10
-
-
0346158376
-
Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation
-
Holness MJ, Sugden MC. Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation. Biochem Soc Trans 31: 1143-1151, 2003.
-
(2003)
Biochem Soc Trans
, vol.31
, pp. 1143-1151
-
-
Holness, M.J.1
Sugden, M.C.2
-
11
-
-
70350287827
-
In vivo carbon-13 dynamic MRS and MRSI of normal and fasted rat liver with hyperpolarized 13C-pyruvate
-
Hu S, Chen AP, Zierhut ML, Bok R, Yen YF, Schroeder MA, Hurd RE, Nelson SJ, Kurhanewicz J, Vigneron DB. In vivo carbon-13 dynamic MRS and MRSI of normal and fasted rat liver with hyperpolarized 13C-pyruvate. Mol Imaging Biol 11: 399-407, 2009.
-
(2009)
Mol Imaging Biol
, vol.11
, pp. 399-407
-
-
Hu, S.1
Chen, A.P.2
Zierhut, M.L.3
Bok, R.4
Yen, Y.F.5
Schroeder, M.A.6
Hurd, R.E.7
Nelson, S.J.8
Kurhanewicz, J.9
Vigneron, D.B.10
-
12
-
-
84868652584
-
13C]pyruvate to probe the effects of the anticancer agent dichloroacetate on mitochondrial metabolism in vivo in the normal rat
-
13C]pyruvate to probe the effects of the anticancer agent dichloroacetate on mitochondrial metabolism in vivo in the normal rat. Magn Reson Imaging 30: 1367-1372, 2012.
-
(2012)
Magn Reson Imaging
, vol.30
, pp. 1367-1372
-
-
Hu, S.1
Yoshihara, H.A.I.2
Bok, R.3
Zhou, J.4
Zhu, M.5
Kurhanewicz, J.6
Vigneron, D.B.7
-
13
-
-
28844467559
-
Propionyl-L-carnitine improves hemodynamics and metabolic markers of cardiac perfusion during coronary surgery in diabetic patients
-
Lango R, Smolenski RT, Rogowski J, Siebert J, Wujtewicz M, Slominska EM, Lysiak-Szydlowska W, Yacoub MH. Propionyl-L-carnitine improves hemodynamics and metabolic markers of cardiac perfusion during coronary surgery in diabetic patients. Cardiovasc Drugs Ther 19: 267-275, 2005.
-
(2005)
Cardiovasc Drugs Ther
, vol.19
, pp. 267-275
-
-
Lango, R.1
Smolenski, R.T.2
Rogowski, J.3
Siebert, J.4
Wujtewicz, M.5
Slominska, E.M.6
Lysiak-Szydlowska, W.7
Yacoub, M.H.8
-
14
-
-
0022388522
-
Regulation of pyruvate dehydrogenase during infusion of fatty acids of varying chain lengths in the perfused rat heart
-
Latipaa PM, Peuhkurinen KJ, Hiltunen JK, Hassinen IE. Regulation of pyruvate dehydrogenase during infusion of fatty acids of varying chain lengths in the perfused rat heart. J Mol Cell Cardiol 17: 1161-1171, 1985.
-
(1985)
J Mol Cell Cardiol
, vol.17
, pp. 1161-1171
-
-
Latipaa, P.M.1
Peuhkurinen, K.J.2
Hiltunen, J.K.3
Hassinen, I.E.4
-
15
-
-
78349287684
-
Rapid multislice imaging of hyperpolarized 13C pyruvate and bicarbonate in the heart
-
Lau AZ, Chen AP, Ghugre NR, Ramanan V, Lam WW, Connelly KA, Wright GA, Cunningham CH. Rapid multislice imaging of hyperpolarized 13C pyruvate and bicarbonate in the heart. Magn Reson Med 64: 1323-1331, 2010.
-
(2010)
Magn Reson Med
, vol.64
, pp. 1323-1331
-
-
Lau, A.Z.1
Chen, A.P.2
Ghugre, N.R.3
Ramanan, V.4
Lam, W.W.5
Connelly, K.A.6
Wright, G.A.7
Cunningham, C.H.8
-
16
-
-
84885953207
-
13C]pyruvate MRS studies by infusion of glucose, insulin and potassium
-
13C]pyruvate MRS studies by infusion of glucose, insulin and potassium. NMR Biomed 26: 1496-1500, 2013.
-
(2013)
NMR Biomed
, vol.26
, pp. 1496-1500
-
-
Lauritzen, M.H.1
Laustsen, C.2
Butt, S.A.3
Magnusson, P.4
Søgaard, L.V.5
Ardenkjær-Larsen, J.H.6
Åkeson, P.7
-
18
-
-
80052854052
-
Could 13C MRI assist clinical decision-making for patients with heart disease?
-
Malloy CR, Merritt ME, Dean Sherry A. Could 13C MRI assist clinical decision-making for patients with heart disease? NMR Biomed 24: 973-979, 2011.
-
(2011)
NMR Biomed
, vol.24
, pp. 973-979
-
-
Malloy, C.R.1
Merritt, M.E.2
Dean Sherry, A.3
-
21
-
-
0025361914
-
Contribution of exogenous substrates to acetyl coenzyme A: Measurement by 13C NMR under non-steady-state conditions
-
Malloy CR, Thompson JR, Jeffrey FM, Sherry AD. Contribution of exogenous substrates to acetyl coenzyme A: measurement by 13C NMR under non-steady-state conditions. Biochemistry 29: 6756-6761, 1990.
-
(1990)
Biochemistry
, vol.29
, pp. 6756-6761
-
-
Malloy, C.R.1
Thompson, J.R.2
Jeffrey, F.M.3
Sherry, A.D.4
-
22
-
-
0037305741
-
Quantitative assessment of anaplerosis from propionate in pig heart in vivo
-
Martini WZ, Stanley WC, Huang H, Rosiers CD, Hoppel CL, Brunengraber H. Quantitative assessment of anaplerosis from propionate in pig heart in vivo. Am J Physiol Endocrinol Metab 284: E351-E356, 2003.
-
(2003)
Am J Physiol Endocrinol Metab
, vol.284
, pp. E351-E356
-
-
Martini, W.Z.1
Stanley, W.C.2
Huang, H.3
Rosiers, C.D.4
Hoppel, C.L.5
Brunengraber, H.6
-
23
-
-
84866296067
-
13C]lactate for the in vivo investigation of cardiac metabolism
-
13C]lactate for the in vivo investigation of cardiac metabolism. NMR Biomed 25: 1119-1124, 2012.
-
(2012)
NMR Biomed
, vol.25
, pp. 1119-1124
-
-
Mayer, D.1
Yen, Y.F.2
Josan, S.3
Park, J.M.4
Pfefferbaum, A.5
Hurd, R.E.6
Spielman, D.M.7
-
24
-
-
82755168823
-
Flux through hepatic pyruvate carboxylase and phosphoenolpyruvate carboxykinase detected by hyperpolarized 13C magnetic resonance
-
Merritt ME, Harrison C, Sherry AD, Malloy CR, Burgess SC. Flux through hepatic pyruvate carboxylase and phosphoenolpyruvate carboxykinase detected by hyperpolarized 13C magnetic resonance. Proc Natl Acad Sci USA 108: 19084-19089, 2011.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 19084-19089
-
-
Merritt, M.E.1
Harrison, C.2
Sherry, A.D.3
Malloy, C.R.4
Burgess, S.C.5
-
25
-
-
38049103113
-
Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR
-
Merritt ME, Harrison C, Storey C, Jeffrey FM, Sherry AD, Malloy CR. Hyperpolarized 13C allows a direct measure of flux through a single enzyme-catalyzed step by NMR. Proc Natl Acad Sci USA 104: 19773-19777, 2007.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19773-19777
-
-
Merritt, M.E.1
Harrison, C.2
Storey, C.3
Jeffrey, F.M.4
Sherry, A.D.5
Malloy, C.R.6
-
28
-
-
84883879044
-
13C]pyruvate
-
13C]pyruvate. Sci Transl Med 5: 198ra108, 2013.
-
(2013)
Sci Transl Med
, vol.5
-
-
Nelson, S.J.1
Kurhanewicz, J.2
Vigneron, D.B.3
Larson, P.E.4
Harzstark, A.L.5
Ferrone, M.6
van Criekinge, M.7
Chang, J.W.8
Bok, R.9
Park, I.10
Reed, G.11
Carvajal, L.12
Small, E.J.13
Munster, P.14
Weinberg, V.K.15
Ardenkjaer-Larsen, J.H.16
Chen, A.P.17
Hurd, R.E.18
Odegardstuen, L.I.19
Robb, F.J.20
Tropp, J.21
Murray, J.A.22
more..
-
29
-
-
0019880617
-
Elimination and replenishment of tricarboxylic acid-cycle intermediates in myocardium
-
Nuutinen EM, Peuhkurinen KJ, Pietilainen EP, Hiltunen JK, Hassinen IE. Elimination and replenishment of tricarboxylic acid-cycle intermediates in myocardium. Biochem J 194: 867-875, 1981.
-
(1981)
Biochem J
, vol.194
, pp. 867-875
-
-
Nuutinen, E.M.1
Peuhkurinen, K.J.2
Pietilainen, E.P.3
Hiltunen, J.K.4
Hassinen, I.E.5
-
30
-
-
0020064865
-
Pyruvate carboxylation as an anaplerotic mechanism in the isolated perfused rat heart
-
Peuhkurinen KJ, Hassinen IE. Pyruvate carboxylation as an anaplerotic mechanism in the isolated perfused rat heart. Biochem J 202: 67-76, 1982.
-
(1982)
Biochem J
, vol.202
, pp. 67-76
-
-
Peuhkurinen, K.J.1
Hassinen, I.E.2
-
31
-
-
0021103326
-
Metabolic compartmentation of pyruvate in the isolated perfused rat heart
-
Peuhkurinen KJ, Hiltunen JK, Hassinen IE. Metabolic compartmentation of pyruvate in the isolated perfused rat heart. Biochem J 210: 193-198, 1983.
-
(1983)
Biochem J
, vol.210
, pp. 193-198
-
-
Peuhkurinen, K.J.1
Hiltunen, J.K.2
Hassinen, I.E.3
-
32
-
-
0013772629
-
Regulation of glucose uptake by muscle. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles
-
Randle PJ, Newsholme EA, Garland PB. Regulation of glucose uptake by muscle. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles. Biochem J 93: 652-665, 1964.
-
(1964)
Biochem J
, vol.93
, pp. 652-665
-
-
Randle, P.J.1
Newsholme, E.A.2
Garland, P.B.3
-
33
-
-
66149087361
-
The effect of hyperpolarized tracer concentration on myocardial uptake and metabolism
-
Schroeder MA, Atherton HJ, Cochlin LE, Clarke K, Radda GK, Tyler DJ. The effect of hyperpolarized tracer concentration on myocardial uptake and metabolism. Magn Reson Med 61: 1007-1014, 2009.
-
(2009)
Magn Reson Med
, vol.61
, pp. 1007-1014
-
-
Schroeder, M.A.1
Atherton, H.J.2
Cochlin, L.E.3
Clarke, K.4
Radda, G.K.5
Tyler, D.J.6
-
34
-
-
80052855442
-
13C]pyruvate
-
13C]pyruvate. NMR Biomed 24: 980-987, 2011.
-
(2011)
NMR Biomed
, vol.24
, pp. 980-987
-
-
Schroeder, M.A.1
Atherton, H.J.2
Heather, L.C.3
Griffin, J.L.4
Clarke, K.5
Radda, G.K.6
Tyler, D.J.7
-
35
-
-
50149105620
-
In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance
-
Schroeder MA, Cochlin LE, Heather LC, Clarke K, Radda GK, Tyler DJ. In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance. Proc Natl Acad Sci USA 105: 12051-12056, 2008.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 12051-12056
-
-
Schroeder, M.A.1
Cochlin, L.E.2
Heather, L.C.3
Clarke, K.4
Radda, G.K.5
Tyler, D.J.6
-
36
-
-
84872515091
-
13C magnetic resonance reveals early-and late-onset changes to in vivo pyruvate metabolism in the failing heart
-
13C magnetic resonance reveals early-and late-onset changes to in vivo pyruvate metabolism in the failing heart. Eur J Heart Fail 15: 130-140, 2013.
-
(2013)
Eur J Heart Fail
, vol.15
, pp. 130-140
-
-
Schroeder, M.A.1
Lau, A.Z.2
Chen, A.P.3
Gu, Y.4
Nagendran, J.5
Barry, J.6
Hu, X.7
Dyck, J.R.B.8
Tyler, D.J.9
Clarke, K.10
Connelly, K.A.11
Wright, G.A.12
Cunningham, C.H.13
-
37
-
-
0742323131
-
13C isotopomer analysis of complex metabolic conditions: Substrate oxidation, multiple pyruvate cycles, and gluconeogenesis
-
13C isotopomer analysis of complex metabolic conditions: substrate oxidation, multiple pyruvate cycles, and gluconeogenesis. Metab Eng 6: 12-24, 2004.
-
(2004)
Metab Eng
, vol.6
, pp. 12-24
-
-
Sherry, A.D.1
Jeffrey, F.M.2
Malloy, C.R.3
-
39
-
-
33745822008
-
Storage and oxidation of long-chain fatty acids in the C57/BL6 mouse heart as measured by NMR spectroscopy
-
Stowe KA, Burgess SC, Merritt M, Sherry AD, Malloy CR. Storage and oxidation of long-chain fatty acids in the C57/BL6 mouse heart as measured by NMR spectroscopy. FEBS Lett 580: 4282-4287, 2006.
-
(2006)
FEBS Lett
, vol.580
, pp. 4282-4287
-
-
Stowe, K.A.1
Burgess, S.C.2
Merritt, M.3
Sherry, A.D.4
Malloy, C.R.5
-
40
-
-
0023341088
-
+ (corrected)-linked malic enzymes as regulators of the pool size of tricarboxylic acid-cycle intermediates in the perfused rat heart
-
+ (corrected)-linked malic enzymes as regulators of the pool size of tricarboxylic acid-cycle intermediates in the perfused rat heart. Biochem J 243: 853-857, 1987.
-
(1987)
Biochem J
, vol.243
, pp. 853-857
-
-
Sundqvist, K.E.1
Heikkila, J.2
Hassinen, I.E.3
Hiltunen, J.K.4
-
41
-
-
0021224619
-
Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart
-
Sundqvist KE, Peuhkurinen KJ, Kalervo Hiltunen J, Hassinen IE. Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart. Biochim Biophys Acta 801: 429-436, 1984.
-
(1984)
Biochim Biophys Acta
, vol.801
, pp. 429-436
-
-
Sundqvist, K.E.1
Peuhkurinen, K.J.2
Kalervo Hiltunen, J.3
Hassinen, I.E.4
|