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Volumn 307, Issue 8, 2014, Pages H1134-H1141

Propionate stimulates pyruvate oxidation in the presence of acetate

Author keywords

Glucose; Hyperpolarization; Isotopomer analysis; Propionate; Pyruvate; Substrate selection

Indexed keywords

ACETIC ACID; ACETYL COENZYME A; ALANINE; ASPARTIC ACID; BICARBONATE; CARBON DIOXIDE; GLUCOSE; LACTIC ACID; MALIC ACID; PROPIONIC ACID; PYRUVATE DEHYDROGENASE; PYRUVIC ACID; ACETIC ACID DERIVATIVE; PROPIONIC ACID DERIVATIVE;

EID: 84908102413     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00407.2014     Document Type: Article
Times cited : (20)

References (41)
  • 2
    • 79958777022 scopus 로고    scopus 로고
    • Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: A combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study
    • Atherton HJ, Dodd MS, Heather LC, Schroeder MA, Griffin JL, Radda GK, Clarke K, Tyler DJ. Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study. Circulation 123: 2552-2561, 2011.
    • (2011) Circulation , vol.123 , pp. 2552-2561
    • Atherton, H.J.1    Dodd, M.S.2    Heather, L.C.3    Schroeder, M.A.4    Griffin, J.L.5    Radda, G.K.6    Clarke, K.7    Tyler, D.J.8
  • 4
    • 19644362468 scopus 로고    scopus 로고
    • Glucose-insulinpotassium in cardiac surgery: A meta-analysis
    • Bothe W, Olschewski M, Beyersdorf F, Doenst T. Glucose-insulinpotassium in cardiac surgery: a meta-analysis. Ann Thorac Surg 78: 1650-1657, 2004.
    • (2004) Ann Thorac Surg , vol.78 , pp. 1650-1657
    • Bothe, W.1    Olschewski, M.2    Beyersdorf, F.3    Doenst, T.4
  • 5
    • 33745105118 scopus 로고    scopus 로고
    • Anaplerotic molecules: Current and future
    • Brunengraber H, Roe CR. Anaplerotic molecules: current and future. J Inherit Metab Dis 29: 327-331, 2006.
    • (2006) J Inherit Metab Dis , vol.29 , pp. 327-331
    • Brunengraber, H.1    Roe, C.R.2
  • 6
    • 10644296223 scopus 로고    scopus 로고
    • Therapeutic effects of l-carnitine and propionyl-l-carnitine on cardiovascular diseases: A review
    • Ferrari R, Merli E, Cicchitelli G, Mele D, Fucili A, Ceconi C. Therapeutic effects of l-carnitine and propionyl-l-carnitine on cardiovascular diseases: a review. Ann N Y Acad Sci 1033: 79-91, 2004.
    • (2004) Ann N Y Acad Sci , vol.1033 , pp. 79-91
    • Ferrari, R.1    Merli, E.2    Cicchitelli, G.3    Mele, D.4    Fucili, A.5    Ceconi, C.6
  • 7
    • 0013772833 scopus 로고
    • Regulation of glucose uptake by muscle. Effects of fatty acids and ketone bodies, and of alloxandiabetes and starvation, on pyruvate metabolism and on lactate-pyruvate and L-glycerol 3-phosphate-dihydroxyacetone phosphate concentration ratios in rat heart and rat diaphragm muscles
    • Garland PB, Newsholme EA, Randle PJ. Regulation of glucose uptake by muscle. Effects of fatty acids and ketone bodies, and of alloxandiabetes and starvation, on pyruvate metabolism and on lactate-pyruvate and L-glycerol 3-phosphate-dihydroxyacetone phosphate concentration ratios in rat heart and rat diaphragm muscles. Biochem J 93: 665-678, 1964.
    • (1964) Biochem J , vol.93 , pp. 665-678
    • Garland, P.B.1    Newsholme, E.A.2    Randle, P.J.3
  • 10
    • 0346158376 scopus 로고    scopus 로고
    • Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation
    • Holness MJ, Sugden MC. Regulation of pyruvate dehydrogenase complex activity by reversible phosphorylation. Biochem Soc Trans 31: 1143-1151, 2003.
    • (2003) Biochem Soc Trans , vol.31 , pp. 1143-1151
    • Holness, M.J.1    Sugden, M.C.2
  • 14
    • 0022388522 scopus 로고
    • Regulation of pyruvate dehydrogenase during infusion of fatty acids of varying chain lengths in the perfused rat heart
    • Latipaa PM, Peuhkurinen KJ, Hiltunen JK, Hassinen IE. Regulation of pyruvate dehydrogenase during infusion of fatty acids of varying chain lengths in the perfused rat heart. J Mol Cell Cardiol 17: 1161-1171, 1985.
    • (1985) J Mol Cell Cardiol , vol.17 , pp. 1161-1171
    • Latipaa, P.M.1    Peuhkurinen, K.J.2    Hiltunen, J.K.3    Hassinen, I.E.4
  • 18
    • 80052854052 scopus 로고    scopus 로고
    • Could 13C MRI assist clinical decision-making for patients with heart disease?
    • Malloy CR, Merritt ME, Dean Sherry A. Could 13C MRI assist clinical decision-making for patients with heart disease? NMR Biomed 24: 973-979, 2011.
    • (2011) NMR Biomed , vol.24 , pp. 973-979
    • Malloy, C.R.1    Merritt, M.E.2    Dean Sherry, A.3
  • 21
    • 0025361914 scopus 로고
    • Contribution of exogenous substrates to acetyl coenzyme A: Measurement by 13C NMR under non-steady-state conditions
    • Malloy CR, Thompson JR, Jeffrey FM, Sherry AD. Contribution of exogenous substrates to acetyl coenzyme A: measurement by 13C NMR under non-steady-state conditions. Biochemistry 29: 6756-6761, 1990.
    • (1990) Biochemistry , vol.29 , pp. 6756-6761
    • Malloy, C.R.1    Thompson, J.R.2    Jeffrey, F.M.3    Sherry, A.D.4
  • 24
    • 82755168823 scopus 로고    scopus 로고
    • Flux through hepatic pyruvate carboxylase and phosphoenolpyruvate carboxykinase detected by hyperpolarized 13C magnetic resonance
    • Merritt ME, Harrison C, Sherry AD, Malloy CR, Burgess SC. Flux through hepatic pyruvate carboxylase and phosphoenolpyruvate carboxykinase detected by hyperpolarized 13C magnetic resonance. Proc Natl Acad Sci USA 108: 19084-19089, 2011.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 19084-19089
    • Merritt, M.E.1    Harrison, C.2    Sherry, A.D.3    Malloy, C.R.4    Burgess, S.C.5
  • 30
    • 0020064865 scopus 로고
    • Pyruvate carboxylation as an anaplerotic mechanism in the isolated perfused rat heart
    • Peuhkurinen KJ, Hassinen IE. Pyruvate carboxylation as an anaplerotic mechanism in the isolated perfused rat heart. Biochem J 202: 67-76, 1982.
    • (1982) Biochem J , vol.202 , pp. 67-76
    • Peuhkurinen, K.J.1    Hassinen, I.E.2
  • 31
    • 0021103326 scopus 로고
    • Metabolic compartmentation of pyruvate in the isolated perfused rat heart
    • Peuhkurinen KJ, Hiltunen JK, Hassinen IE. Metabolic compartmentation of pyruvate in the isolated perfused rat heart. Biochem J 210: 193-198, 1983.
    • (1983) Biochem J , vol.210 , pp. 193-198
    • Peuhkurinen, K.J.1    Hiltunen, J.K.2    Hassinen, I.E.3
  • 32
    • 0013772629 scopus 로고
    • Regulation of glucose uptake by muscle. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles
    • Randle PJ, Newsholme EA, Garland PB. Regulation of glucose uptake by muscle. Effects of fatty acids, ketone bodies and pyruvate, and of alloxan-diabetes and starvation, on the uptake and metabolic fate of glucose in rat heart and diaphragm muscles. Biochem J 93: 652-665, 1964.
    • (1964) Biochem J , vol.93 , pp. 652-665
    • Randle, P.J.1    Newsholme, E.A.2    Garland, P.B.3
  • 35
    • 50149105620 scopus 로고    scopus 로고
    • In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance
    • Schroeder MA, Cochlin LE, Heather LC, Clarke K, Radda GK, Tyler DJ. In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance. Proc Natl Acad Sci USA 105: 12051-12056, 2008.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 12051-12056
    • Schroeder, M.A.1    Cochlin, L.E.2    Heather, L.C.3    Clarke, K.4    Radda, G.K.5    Tyler, D.J.6
  • 37
    • 0742323131 scopus 로고    scopus 로고
    • 13C isotopomer analysis of complex metabolic conditions: Substrate oxidation, multiple pyruvate cycles, and gluconeogenesis
    • 13C isotopomer analysis of complex metabolic conditions: substrate oxidation, multiple pyruvate cycles, and gluconeogenesis. Metab Eng 6: 12-24, 2004.
    • (2004) Metab Eng , vol.6 , pp. 12-24
    • Sherry, A.D.1    Jeffrey, F.M.2    Malloy, C.R.3
  • 39
    • 33745822008 scopus 로고    scopus 로고
    • Storage and oxidation of long-chain fatty acids in the C57/BL6 mouse heart as measured by NMR spectroscopy
    • Stowe KA, Burgess SC, Merritt M, Sherry AD, Malloy CR. Storage and oxidation of long-chain fatty acids in the C57/BL6 mouse heart as measured by NMR spectroscopy. FEBS Lett 580: 4282-4287, 2006.
    • (2006) FEBS Lett , vol.580 , pp. 4282-4287
    • Stowe, K.A.1    Burgess, S.C.2    Merritt, M.3    Sherry, A.D.4    Malloy, C.R.5
  • 40
    • 0023341088 scopus 로고
    • + (corrected)-linked malic enzymes as regulators of the pool size of tricarboxylic acid-cycle intermediates in the perfused rat heart
    • + (corrected)-linked malic enzymes as regulators of the pool size of tricarboxylic acid-cycle intermediates in the perfused rat heart. Biochem J 243: 853-857, 1987.
    • (1987) Biochem J , vol.243 , pp. 853-857
    • Sundqvist, K.E.1    Heikkila, J.2    Hassinen, I.E.3    Hiltunen, J.K.4
  • 41
    • 0021224619 scopus 로고
    • Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart
    • Sundqvist KE, Peuhkurinen KJ, Kalervo Hiltunen J, Hassinen IE. Effect of acetate and octanoate on tricarboxylic acid cycle metabolite disposal during propionate oxidation in the perfused rat heart. Biochim Biophys Acta 801: 429-436, 1984.
    • (1984) Biochim Biophys Acta , vol.801 , pp. 429-436
    • Sundqvist, K.E.1    Peuhkurinen, K.J.2    Kalervo Hiltunen, J.3    Hassinen, I.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.