Competition of pyruvate with physiological substrates for oxidation by the heart: Implications for studies with hyperpolarized [1-13C]pyruvate

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 298, Issue 5, 2010, Pages

  Moreno, Karlos X ^a   Sabelhaus, Scott M ^a   Merritt, Matthew E ^a   Sherry, A Dean ^a   Malloy, Craig R ^a,b  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

Author keywords

Carbon 13; Dynamic nuclear polarization; Isolated rat heart; Myocardium; Nuclear magnetic resonance; Pyruvate; Substrate oxidation

Indexed keywords

ACETYL COENZYME A; KETONE; LONG CHAIN FATTY ACID; PYRUVIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY; ENZYME SUBSTRATE; HEART HEMODYNAMICS; HEART MUSCLE METABOLISM; HEART OUTPUT; HEART PERFUSION; HYPERPOLARIZATION; ISOLATED HEART; MALE; MOLECULAR MIMICRY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT;

ACETYL COENZYME A; ALBUMINS; ANIMALS; CARBON RADIOISOTOPES; CARDIAC OUTPUT; CORONARY VESSELS; HEART FUNCTION TESTS; HEMODYNAMICS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MYOCARDIUM; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; PYRUVIC ACID; RATS; RATS, SPRAGUE-DAWLEY;

EID: 77951836661     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00656.2009     Document Type: Article

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