Crystal structure of a fanconi anemiaassociated nuclease homolog bound to 5′ flap DNA: Basis of interstrand cross-link repair by FAN1

Genes and Development

Volumn 28, Issue 20, 2014, Pages 2276-2290

  Gwon, Gwang Hyeon ^a   Kim, Youngran ^a   Liu, Yaqi ^a   Watson, Adam T ^b   Jo, Aera ^a   Etheridge, Thomas J ^b   Yuan, Fenghua ^c   Zhang, Yanbin ^c   Kim, Youngchang ^d   Carr, Anthony M ^b   Cho, Yunje ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

^c UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^d ARGONNE NATIONAL LABORATORY   (United States)

Author keywords

Crystal structure; Fanconi anemia nuclease 1; Interstrand cross link repair

Indexed keywords

FANCONI ANEMIA ASSOCIATED NUCLEASE 1; NUCLEASE; PHOSPHATE; PROTEIN UBZ; UBIQUITIN; UNCLASSIFIED DRUG; VIRUS REPLICATION AND REPAIR NUCLEASE; EXODEOXYRIBONUCLEASE; FLAP ENDONUCLEASE; PROTEIN BINDING;

5' UNTRANSLATED REGION; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA CROSS LINKING; ENZYME MECHANISM; HOLLIDAY JUNCTION; MOLECULAR RECOGNITION; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DNA BINDING; PROTEIN DOMAIN; PSEUDOMONAS AERUGINOSA; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYMOLOGY; HUMAN; METABOLISM; PROTEIN TERTIARY STRUCTURE;

CATALYTIC DOMAIN; CRYSTALLIZATION; EXODEOXYRIBONUCLEASES; FLAP ENDONUCLEASES; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA;

EID: 84908101886     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.248492.114     Document Type: Article

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