FAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domain

Cell Reports

Volumn 8, Issue 1, 2014, Pages 84-93

  Pennell, Simon ^a   Déclais, Anne Cécile ^b   Li, Jiejin ^a   Haire, Lesley F ^a   Berg, Wioletta ^a   Saldanha, JoséW ^a   Taylor, Ian A ^a   Rouse, John ^b   Lilley, David M J ^b   Smerdon, Stephen J ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CROSSOVER JUNCTION ENDODEOXYRIBONUCLEASE; FANCD2 ASSOCIATED NUCLEASE 1; NUCLEASE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CRUCIFORM DNA; DEOXYRIBONUCLEASE; EXODEOXYRIBONUCLEASE; FAN1 PROTEIN, HUMAN; FAN1 PROTEIN, MOUSE; PROTEIN BINDING; FANCD2 FANCI ASSOCIATED NUCLEASE 1;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; IN VITRO STUDY; MOLECULAR MODEL; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VIRUS TYPE REPLICATION REPAIR DOMAIN; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; DNA REPAIR; ENZYMOLOGY; HUMAN; METABOLISM; MOLECULAR GENETICS; MOUSE; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE; PSEUDOMONAS AERUGINOSA; CATALYSIS; ENZYME ANALYSIS; ENZYME DEGRADATION; ENZYME STRUCTURE; HOLLIDAY JUNCTION; NONHUMAN; ORTHOLOGY; STRUCTURAL HOMOLOGY;

EUKARYOTA;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; DNA REPAIR; DNA, CRUCIFORM; ENDODEOXYRIBONUCLEASES; EXODEOXYRIBONUCLEASES; HOLLIDAY JUNCTION RESOLVASES; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA;

EID: 84904036917     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.06.001     Document Type: Article

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