Recent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: Novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor

BMC Endocrine Disorders

Volumn 14, Issue 1, 2014, Pages

  Nicolaides, Nicolas C ^a,b   Charmandari, Evangelia ^a,b   Chrousos, George P ^a,b,c   Kino, Tomoshige ^d  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^c KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^d EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Glucocorticoid hypersensitivity; Glucocorticoid receptor; Glucocorticoid resistance; Glucocorticoid signal transduction

Indexed keywords

GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; LIGAND; ISOPROTEIN;

ARTICLE; CHROUSOS SYNDROME; CIRCADIAN RHYTHM; DOWN REGULATION; GENE; GENE EXPRESSION; GENE MUTATION; GENE REPRESSION; GENETIC DISORDER; HORMONE PROTEIN COMPLEX; HUMAN; HUMAN GLUCOCORTICOID RECEPTOR GENE; LIGAND BINDING; MOLECULAR CLOCK; MOLECULAR PATHOLOGY; PLEIOTROPY; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TARGET ORGAN; TISSUE REACTION; TISSUE SPECIFICITY; ANTAGONISTS AND INHIBITORS; BIOLOGICAL MODEL; DRUG RESISTANCE; GENETICS; MUTATION; PHYSIOLOGY;

CIRCADIAN RHYTHM; DRUG RESISTANCE; GLUCOCORTICOIDS; HUMANS; LIGANDS; MODELS, BIOLOGICAL; MUTATION; PROTEIN ISOFORMS; RECEPTORS, GLUCOCORTICOID; SIGNAL TRANSDUCTION;

EID: 84908070651     PISSN: None     EISSN: 14726823     Source Type: Journal    
DOI: 10.1186/1472-6823-14-71     Document Type: Article

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