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Volumn 38, Issue 1, 2012, Pages 11-17

Enhanced steroid response of a human glucocorticoid receptor splice variant

Author keywords

alternative splicing; Glucocorticoid receptor; hGR; hGR S1( 349A); hGRS1; human glucocorticoid receptor; steroid response

Indexed keywords

GLUCOCORTICOID RECEPTOR ALPHA; GLUCOCORTICOID RECEPTOR BETA; HYDROCORTISONE; ISOPROTEIN; METHYLPREDNISOLONE; STEROID;

EID: 84862743409     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0b013e318257c0c0     Document Type: Article
Times cited : (19)

References (34)
  • 2
    • 18144399332 scopus 로고    scopus 로고
    • The human glucocorticoid receptor: One gene, multiple proteins and diverse responses
    • DOI 10.1016/j.steroids.2005.02.006
    • Zhou J, Cidlowski JA: The human glucocorticoid receptor: one gene, multiple proteins and diverse responses. Steroids 70:407-417, 2005. (Pubitemid 40616039)
    • (2005) Steroids , vol.70 , Issue.SPEC. ISS. , pp. 407-417
    • Zhou, J.1    Cidlowski, J.A.2
  • 3
    • 0037151571 scopus 로고    scopus 로고
    • Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
    • Annane D, Sebille V, Charpentier C, Bollaert PE, Francois B, et al.: Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 288:862-871, 2002.
    • (2002) JAMA , vol.288 , pp. 862-871
    • Annane, D.1    Sebille, V.2    Charpentier, C.3    Bollaert, P.E.4    Francois, B.5
  • 5
    • 0029090390 scopus 로고
    • Corticosteroid treatment for sepsis: A critical appraisal and meta-analysis of the literature
    • Cronin L, Cook DJ, Carlet J, Heyland DK, King D, et al.: Corticosteroid treatment for sepsis: a critical appraisal and meta-analysis of the literature. Crit Care Med 23:1430-1439, 1995.
    • (1995) Crit Care Med , vol.23 , pp. 1430-1439
    • Cronin, L.1    Cook, D.J.2    Carlet, J.3    Heyland, D.K.4    King, D.5
  • 6
  • 8
    • 0034903792 scopus 로고    scopus 로고
    • The natural history of corticosteroid therapy for inflammatory bowel disease: A population-based study
    • Faubion WA Jr, Loftus EV Jr, Harmsen WS, Zinsmeister AR, Sandborn WJ: The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study. Gastroenterology 121:255-260, 2001. (Pubitemid 32729372)
    • (2001) Gastroenterology , vol.121 , Issue.2 , pp. 255-260
    • Faubion Jr., W.A.1    Loftus Jr., E.V.2    Harmsen, W.S.3    Zinsmeister, A.R.4    Sandborn, W.J.5
  • 9
    • 37549020378 scopus 로고    scopus 로고
    • Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
    • Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, et al.: Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 36:296-327, 2008.
    • (2008) Crit Care Med , vol.36 , pp. 296-327
    • Dellinger, R.P.1    Levy, M.M.2    Carlet, J.M.3    Bion, J.4    Parker, M.M.5
  • 10
    • 70449348176 scopus 로고    scopus 로고
    • Mechanisms generating diversity in glucocorticoid receptor signaling
    • Revollo JR, Cidlowski JA: Mechanisms generating diversity in glucocorticoid receptor signaling. Ann N Y Acad Sci 1179:167-178, 2009.
    • (2009) Ann N y Acad Sci , vol.1179 , pp. 167-178
    • Revollo, J.R.1    Cidlowski, J.A.2
  • 11
    • 80052965328 scopus 로고    scopus 로고
    • Novel hyperactive glucocorticoid receptor isoform identified within a human population
    • Tung K, Baker AC, Amini A, Green TL, Chew VW, et al.: Novel hyperactive glucocorticoid receptor isoform identified within a human population. Shock 36:339-344, 2011.
    • (2011) Shock , vol.36 , pp. 339-344
    • Tung, K.1    Baker, A.C.2    Amini, A.3    Green, T.L.4    Chew, V.W.5
  • 12
    • 0022393794 scopus 로고
    • Primary structure and expression of a functional human glucocorticoid receptor cDNA
    • DOI 10.1038/318635a0
    • Hollenberg SM, Weinberger C, Ong ES, Cerelli G, Oro A, et al.: Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature 318:635-641, 1985. (Pubitemid 16172412)
    • (1985) Nature , vol.318 , Issue.6047 , pp. 635-641
    • Hollenberg, S.M.1    Weinberger, C.2    Ong, E.S.3
  • 13
    • 0025895395 scopus 로고
    • The genomic structure of the human glucocorticoid receptor
    • Encio IJ, Detera-Wadleigh SD: The genomic structure of the human glucocorticoid receptor. J Biol Chem 266:7182-7188, 1991. (Pubitemid 21906349)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.11 , pp. 7182-7188
    • Encio, I.J.1    Detera-Wadleigh, S.D.2
  • 14
    • 3042831099 scopus 로고    scopus 로고
    • The origin and functions of multiple human glucocorticoid receptor isoforms
    • DOI 10.1196/annals.1321.008
    • Lu NZ, Cidlowski JA: The origin and functions of multiple human glucocorticoid receptor isoforms. Ann N Y Acad Sci 1024:102-123, 2004. (Pubitemid 38879596)
    • (2004) Annals of the New York Academy of Sciences , vol.1024 , pp. 102-123
    • Nick, Z.L.U.1    Cidlowski, J.A.2
  • 15
    • 0033600936 scopus 로고    scopus 로고
    • The dominant negative activity of the human glucocorticoid receptor beta isoform. Specificity and mechanisms of action
    • Oakley RH, Jewell CM, Yudt MR, Bofetiado DM, Cidlowski JA: The dominant negative activity of the human glucocorticoid receptor beta isoform. Specificity and mechanisms of action. J Biol Chem 274:27857-27866, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 27857-27866
    • Oakley, R.H.1    Jewell, C.M.2    Yudt, M.R.3    Bofetiado, D.M.4    Cidlowski, J.A.5
  • 17
    • 0027169076 scopus 로고
    • Alternatively spliced glucocorticoid receptor messenger RNAs in glucocorticoid-resistant human multiple myeloma cells
    • Moalli PA, Pillay S, Krett NL, Rosen ST: Alternatively spliced glucocorticoid receptor messenger RNAs in glucocorticoid-resistant human multiple myeloma cells. Cancer Res 53:3877-3879, 1993. (Pubitemid 23267681)
    • (1993) Cancer Research , vol.53 , Issue.17 , pp. 3877-3879
    • Moalli, P.A.1    Pillay, S.2    Krett, N.L.3    Rosen, S.T.4
  • 18
    • 0029982833 scopus 로고    scopus 로고
    • Glucocorticoid receptor structure and function in glucocorticoid- resistant small cell lung carcinoma cells
    • Ray DW, Davis JR, White A, Clark AJ: Glucocorticoid receptor structure and function in glucocorticoid-resistant small cell lung carcinoma cells. Cancer Res 56:3276-3280, 1996. (Pubitemid 26242976)
    • (1996) Cancer Research , vol.56 , Issue.14 , pp. 3276-3280
    • Ray, D.W.1    Davis, J.R.E.2    White, A.3    Clark, A.J.L.4
  • 19
    • 0033323794 scopus 로고    scopus 로고
    • Insertion of an amino acid in the DNA-binding domain of the glucocorticoid receptor as a result of alternative splicing
    • Rivers C, Levy A, Hancock J, Lightman S, Norman M: Insertion of an amino acid in the DNA-binding domain of the glucocorticoid receptor as a result of alternative splicing. J Clin Endocrinol Metab 84:4283-4286, 1999. (Pubitemid 30644231)
    • (1999) Journal of Clinical Endocrinology and Metabolism , vol.84 , Issue.11 , pp. 4283-4286
    • Rivers, C.1    Levy, A.2    Hancock, J.3    Lightman, S.4    Norman, M.5
  • 20
    • 0038148315 scopus 로고    scopus 로고
    • Expression and structural analysis of glucocorticoid receptor isoform gamma in human leukaemia cells using an isoform-specific real-time polymerase chain reaction approach
    • DOI 10.1046/j.1365-2141.2003.04426.x
    • Beger C, Gerdes K, Lauten M, Tissing WJ, Fernandez-Munoz I, et al.: Expression and structural analysis of glucocorticoid receptor isoform gamma in human leukaemia cells using an isoform-specific real-time polymerase chain reaction approach. Br J Haematol 122:245-252, 2003. (Pubitemid 36859610)
    • (2003) British Journal of Haematology , vol.122 , Issue.2 , pp. 245-252
    • Beger, C.1    Gerdes, K.2    Lauten, M.3    Tissing, W.J.E.4    Fernandez-Munoz, I.5    Schrappe, M.6    Welte, K.7
  • 21
    • 0029044488 scopus 로고
    • A variant glucocorticoid receptor messenger RNA is expressed in multiple myeloma patients
    • Krett NL, Pillay S, Moalli PA, Greipp PR, Rosen ST: A variant glucocorticoid receptor messenger RNA is expressed in multiple myeloma patients. Cancer Res 55:2727-2729, 1995.
    • (1995) Cancer Res , vol.55 , pp. 2727-2729
    • Krett, N.L.1    Pillay, S.2    Moalli, P.A.3    Greipp, P.R.4    Rosen, S.T.5
  • 22
    • 33846187629 scopus 로고    scopus 로고
    • Glucocorticoid receptor transcriptional isoforms and resistance in multiple myeloma cells
    • DOI 10.1158/1535-7163.MCT-06-0344
    • Sanchez-Vega B, Krett N, Rosen ST, Gandhi V: Glucocorticoid receptor transcriptional isoforms and resistance in multiple myeloma cells. Mol Cancer Ther 5:3062-3070, 2006. (Pubitemid 46092047)
    • (2006) Molecular Cancer Therapeutics , vol.5 , Issue.12 , pp. 3062-3070
    • Sanchez-Vega, B.1    Krett, N.2    Rosen, S.T.3    Gandhi, V.4
  • 23
    • 59849107871 scopus 로고    scopus 로고
    • A novel method for monitoring glucocorticoid-induced changes of the glucocorticoid receptor in kidney transplant recipients
    • Chen Y, Burckart GJ, Shah T, Pravica V, Hutchinson IV: A novel method for monitoring glucocorticoid-induced changes of the glucocorticoid receptor in kidney transplant recipients. Transpl Immunol 20:249-252, 2009.
    • (2009) Transpl Immunol , vol.20 , pp. 249-252
    • Chen, Y.1    Burckart, G.J.2    Shah, T.3    Pravica, V.4    Hutchinson, I.V.5
  • 24
    • 18844424643 scopus 로고    scopus 로고
    • Human glucocorticoid receptor α transcript splice variants with exon 2 deletions: Evidence for tissue- and cell type-specific functions
    • DOI 10.1021/bi047485e
    • Geng CD, Pedersen KB, Nunez BS, Vedeckis WV: Human glucocorticoid receptor alpha transcript splice variants with exon 2 deletions: evidence for tissue-and cell type-specific functions. Biochemistry 44:7395-7405, 2005. (Pubitemid 40695993)
    • (2005) Biochemistry , vol.44 , Issue.20 , pp. 7395-7405
    • Geng, C.-D.1    Pedersen, K.B.2    Nunez, B.S.3    Vedeckis, W.V.4
  • 25
    • 67649386557 scopus 로고    scopus 로고
    • Glucocorticoid receptor mRNA levels are selectively decreased in neutrophils of children with sepsis
    • van den Akker EL, Koper JW, Joosten K, de Jong FH, Hazelzet JA, et al.: Glucocorticoid receptor mRNA levels are selectively decreased in neutrophils of children with sepsis. Intensive Care Med 35:1247-1254, 2009.
    • (2009) Intensive Care Med , vol.35 , pp. 1247-1254
    • Van Den Akker, E.L.1    Koper, J.W.2    Joosten, K.3    De Jong, F.H.4    Hazelzet, J.A.5
  • 27
    • 77951120000 scopus 로고    scopus 로고
    • Alternative splicing and evolution: Diversification, exon definition and function
    • Keren H, Lev-Maor G, Ast G: Alternative splicing and evolution: diversification, exon definition and function. Nat Rev Genet 11:345-355, 2010.
    • (2010) Nat Rev Genet , vol.11 , pp. 345-355
    • Keren, H.1    Lev-Maor, G.2    Ast, G.3
  • 29
    • 45849083124 scopus 로고    scopus 로고
    • The effect of CAG repeat length polymorphism in the murine glucocorticoid receptor on transactivation potential
    • Yee KS, Cho K, Green T, Chandler J, Greenhalgh DG: The effect of CAG repeat length polymorphism in the murine glucocorticoid receptor on transactivation potential. Exp Mol Pathol 84:200-205, 2008.
    • (2008) Exp Mol Pathol , vol.84 , pp. 200-205
    • Yee, K.S.1    Cho, K.2    Green, T.3    Chandler, J.4    Greenhalgh, D.G.5
  • 30
    • 33645220078 scopus 로고    scopus 로고
    • CD14-dependent modulation of NF-kappaB alternative splicing in the lung after burn injury
    • Phan HH, Cho K, Sainz-Lyon KS, Shin S, Greenhalgh DG: CD14-dependent modulation of NF-kappaB alternative splicing in the lung after burn injury. Gene 371:121-129, 2006.
    • (2006) Gene , vol.371 , pp. 121-129
    • Phan, H.H.1    Cho, K.2    Sainz-Lyon, K.S.3    Shin, S.4    Greenhalgh, D.G.5
  • 32
    • 0034101197 scopus 로고    scopus 로고
    • The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology?
    • DOI 10.1038/76211
    • Conne B, Stutz A, Vassalli JD: The 3¶ untranslated region of messenger RNA: a molecular 'hotspot' for pathology? Nat Med 6:637-641, 2000. (Pubitemid 30398786)
    • (2000) Nature Medicine , vol.6 , Issue.6 , pp. 637-641
    • Conne, B.1    Stutz, A.2    Vassalli, J.-D.3
  • 33
    • 69549135202 scopus 로고    scopus 로고
    • To localize or not to localize: MRNA fate is in 3¶UTR ends
    • Andreassi C, Riccio A: To localize or not to localize: mRNA fate is in 3¶UTR ends. Trends Cell Biol 19:465-474, 2009.
    • (2009) Trends Cell Biol , vol.19 , pp. 465-474
    • Andreassi, C.1    Riccio, A.2
  • 34
    • 0036240969 scopus 로고    scopus 로고
    • AUUUA motifs in the 3′UTR of human glucocorticoid receptor α and β mRNA destabilize mRNA and decrease receptor protein expression
    • DOI 10.1016/S0039-128X(02)00015-6, PII S0039128X02000156
    • Schaaf MJ, Cidlowski JA: AUUUA motifs in the 3¶UTR of human glucocorticoid receptor alpha and beta mRNA destabilize mRNA and decrease receptor protein expression. Steroids 67:627-636, 2002. (Pubitemid 34462990)
    • (2002) Steroids , vol.67 , Issue.7 , pp. 627-636
    • Schaaf, M.J.M.1    Cidlowski, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.