A novel point mutation in helix 11 of the ligand-binding domain of the human glucocorticoid receptor gene causing generalized glucocorticoid resistance

Journal of Clinical Endocrinology and Metabolism

Volumn 92, Issue 10, 2007, Pages 3986-3990

  Charmandari, Evangelia ^a,d   Kino, Tomoshige ^a   Ichijo, Takamasa ^a   Jubiz, William ^c   Mejia, Liliana ^c   Zachman, Keith ^a   Chrousos, George P ^a,b  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^c FUNDACIÓN VALLE DEL LILI   (Colombia)

^d BIOMEDICAL RESEARCH FOUNDATION   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR ALPHA; GLUTATHIONE TRANSFERASE; HELIX LOOP HELIX PROTEIN; HYDROCORTISONE; LEUCINE; PHENYLALANINE; POTASSIUM;

ADRENAL HYPERPLASIA; AMINO ACID SUBSTITUTION; ARTICLE; CASE REPORT; CHROMATIN IMMUNOPRECIPITATION; COMPUTER ASSISTED TOMOGRAPHY; DEXAMETHASONE SUPPRESSION TEST; DIASTOLIC BLOOD PRESSURE; DNA BINDING; EXON; GENE SEQUENCE; GENE TRANSLOCATION; GLUCOCORTICOID RESISTANCE; HETEROZYGOSITY; HORMONE RESISTANCE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPERTENSION; HYPOKALEMIA; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LIGAND BINDING; MALE; MOUSE MAMMARY TUMOR ONCOVIRUS; NUCLEAR MAGNETIC RESONANCE IMAGING; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTERACTION; RECEPTOR AFFINITY; SCHOOL CHILD; SIGNAL TRANSDUCTION; SYSTOLIC BLOOD PRESSURE; THORAX RADIOGRAPHY; TRANSACTIVATION; WESTERN BLOTTING; WILD TYPE;

MOUSE MAMMARY TUMOR VIRUS;

EID: 35349002759     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2006-2830     Document Type: Article

References (20)

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