Surface functionalized mesoporous silica nanoparticles with natural proteins for reduced immunotoxicity

Journal of Biomedical Materials Research - Part A

Volumn 102, Issue 11, 2014, Pages 3781-3794

  Luo, Zhong ^a   Hu, Yan ^a   Xin, Renlong ^a   Zhang, Beilu ^a   Li, Jinghua ^a   Ding, Xingwei ^a   Hou, Yanhua ^a   Yang, Li ^a   Cai, Kaiyong ^a  

^a CHONGQING UNIVERSITY   (China)

Author keywords

Immunotoxicity; Inflammation responses; Macrophages; Mesoporous silica nanoparticles; Natural proteins

Indexed keywords

CELL DEATH; CONTROLLED DRUG DELIVERY; MACROPHAGES; MAMMALS; MESOPOROUS MATERIALS; MORPHOLOGY; NANOCOMPOSITES; NANOPARTICLES; NITRIC OXIDE; PATHOLOGY; PHOSPHATASES; SILICA; SILICA NANOPARTICLES; TARGETED DRUG DELIVERY;

ACID PHOSPHATASE ACTIVITIES; BOVINE SERUM ALBUMINS; CONSTRUCTION PROCESS; IMMUNOTOXICITY; INFLAMMATION RESPONSES; MESOPOROUS SILICA NANOPARTICLES; NATURAL PROTEINS; TUMOR NECROSIS FACTOR ALPHA;

SIO2 NANOPARTICLES;

ACID PHOSPHATASE; BOVINE SERUM ALBUMIN; GELATIN; INTERLEUKIN 1BETA; LYSOZYME; MESOPOROUS SILICA NANOPARTICLE; NANOPARTICLE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SILICON DIOXIDE; SUCCINIC ANHYDRIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; DRUG CARRIER; NANOCOMPOSITE;

ARTICLE; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENZYME ACTIVITY; IMMUNOTOXICITY; IN VITRO STUDY; INFLAMMATION; INFRARED SPECTROSCOPY; MACROPHAGE; MACROPHAGE ACTIVATION; NANOFABRICATION; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL; ANIMAL; BOVINE; CELL LINE; CHEMISTRY; MATERIALS TESTING; METABOLISM; MOUSE; POROSITY;

ANIMALS; CATTLE; CELL LINE; DRUG CARRIERS; GELATIN; MACROPHAGES; MATERIALS TESTING; MICE; MURAMIDASE; NANOCOMPOSITES; NANOPARTICLES; POROSITY; SERUM ALBUMIN, BOVINE; SILICON DIOXIDE;

EID: 84908069404     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.35049     Document Type: Article

References (60)

1. Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, Langer R. Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol 2007;2:751-760.
2. Wolfgang JP. Complex colloidal assembly. Science 2011;334: 1359-1360.
3. Chen ZL, Li Y, Liu WW, Zhang DZ, Zhao YY, Yuan B, Jiang XY. Patterning mammalian cells for modeling three types of naturally occurring cell-cell interactions. Angew Chem Int Ed 2009;48:8303-8305.
4. Wang XJ, Wang C, Cheng L, Lee ST, Liu Z. Noble metal coated single-walled carbon nanotubes for applications in surface enhanced Raman scattering imaging and photothermal therapy. J Am Chem Soc 2012;134:7414-7422.
5. Dobrovolskaia MA, Germolec DR, Weaver JL. Evaluation of nanoparticle immunotoxicity. Nat Nanotechnol 2009;4:411-414.
6. Dobrovolskaia MA, McNeil SE. Immunological properties of engineered nanomaterials. Nat Nanotechnol 2007;2:469-478.
7. Li LL, Tang FQ, Liu HY, Liu TL, Hao NJ, Chen D, Teng X, He JQ. In vivo delivery of silica nanorattle encapsulated docetaxel for liver cancer therapy with low toxicity and high efficacy. ACS Nano 2010;4:6874-6882.
8. Chen Y, Chu C, Zhou Y, Ru YF, Chen HR, Chen F, He QJ, Zhang YL, Zhang LL, Shi JL. Reversible pore-structure evolution in hollow silica nanocapsules: Large pores for siRNA delivery and nanoparticle collecting. Small 2011;7:2935-2944.
9. Ambrogio MW, Thomas CR, Zhao YL, Zink JI, Stoddart JF. Mechanized silica nanoparticles: A new frontier in theranostic nanomedicine. Acc Chem Res 2011;44:903-913.
10. Lai CY, Trewyn BG, Jeftinija DM, Jeftinija K, Xu S, Jeftinija S, Lin VYS. A mesoporous silica nanosphere-based carrier system with chemically removable CdS nanoparticle caps for stimuliresponsive controlled release of neurotransmitters and drug molecules. J Am Chem Soc 2003;125:4451-4459.
11. Sun X, Zhao Y, Lin VS, Slowing II, Trewyn BG. Luciferase and luciferin co-immobilized mesoporous silica nanoparticle materials for intracellular biocatalysis. J Am Chem Soc 2011;133:18554-18557.
12. Ma M, Chen HR, Chen Y, Wang X, Chen F, Cui XZ, Shi JL. Au capped magnetic core/mesoporous silica shell nanoparticles for combined photothermo-/chemo-therapy and multimodal imaging. Biomaterials 2012;33:989-998.
13. Yan H, Teh C, Sreejith S, Zhu LL, Kwok A, Fang WQ, Ma X, Nguyen KT, Korzh V, Zhao YL. Functional mesoporous silica nanoparticles for photothermal - Controlled drug delivery in vivo. Angew Chem Int Ed 2012;51:8373-8377.
14. Zhao YL, Li Z, Kabehie S, Botros YY, Stoddart JF, Zink JI. pHoperated nanopistons on the surfaces of mesoporous silica nanoparticles. J Am Chem Soc 2010;132:13016-13025.
15. Meng H, Xue M, Xia T, Zhao YL, Tamanoi F, Stoddart JF, Zink JI, Nel AE. Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles derivatized with pH-sensitive supramolecular nanovalves. J Am Chem Soc 2010;132:12690-12697.
16. Luo Z, Cai KY, Hu Y, Zhao L, Liu P, Duan L, Yang WH. Mesoporous silica nanoparticles end-capped with collagen: Redoxresponsive nanoreservoirs for targeted drug delivery. Angew Chem Int Ed 2011;50:640-643.
17. Hu Y, Cai KY, Luo Z, Jandt KD. Layer-by-layer assembly of bestradiol loaded mesoporous silica nanoparticles on titanium substrates and its implication for bone homeostasis. Adv Mater 2010; 22:4146-4150.
18. Luo Z, Cai KY, Hu Y, Zhang BL, Xu DW. Cell-specific intracellular anticancer drug delivery from mesoporous silica nanoparticles with pH-sensitivity. Adv Healthcare Mater 2012;1:321-325.
19. Zhao Y, Trewyn BG, Slowing II, Lin VS. Mesoporous silica nanoparticle-based double drug delivery system for glucose- responsive controlled release of insulin and cyclic AMP. J Am Chem Soc 2009;131:8398-8400.
20. Huang XL, Li LL, Liu TL, Hao NJ, Liu HY, Chen D, Tang FQ. The shape effect of mesoporous silica nanoparticles on biodistribution, clearance, and biocompatibility in vivo. ACS Nano 2011;5: 5390-5399.
21. Zhao F, Zhao Y, Liu Y, Chang X, Chen C, Zhao Y. Cellular uptake, intracellular trafficking, and cytotoxicity of nanomaterials. Small 2011;7:1322-1337.
22. Zhang Y, Hu L, Yu D, Gao C. Influence of silica particle internalization on adhesion and migration of human dermal fibroblasts. Biomaterials 2010;31:8465-8474.
23. Franz S, Rammelt S, Scharnweber D, Simon JC. Immune responses to implants - A review of the implications for the design of immunomodulatory biomaterials. Biomaterials 2011;32: 6692-6709.
24. Mao Z, Zhou X, Gao C. Influence of structure and properties of colloidal biomaterials on cellular uptake and cell functions. Biomater Sci 2013;1:896-911.
25. Hu L, Mao Z, Gao C. Colloidal particles for cellular uptake and delivery. J Mater Chem 2009;19:3108-3115.
26. Hartono SB, Gu WY, Kleitz F, Liu J, He LZ, Middelberg APJ, Yu CZ, LU GQ, Qiao SZ. Poly-l-lysine functionalized large pore cubic mesostructured silica nanoparticles as biocompatible carriers for gene delivery. ACS Nano 2012;6:2104-2117.
27. Schlossbauer A, Kecht J, Bein T. Biotin-avidin as a proteaseresponsive cap system for controlled guest release from colloidal mesoporous silica. Angew Chem Int Ed 2009;48:3092-3095.
28. Climent E, Bernardos A, Martínez-Máñez R, Maquieira A, Marcos MD, Pastor-Navarro N, Puchades R, Sancenon F, Soto J, Amoros P. Controlled delivery systems using antibody-capped mesoporous nanocontainers. J Am Chem Soc 2009;131:4075-4080.
29. Schlossbauer A, Warncke S, Gramlich PM, Kecht J, Manetto A, Carell T, Bein T. A programmable DNA-based molecular valve for colloidal mesoporous silica. Angew Chem Int Ed 2010;49:4734-4737.
30. Muszanska AK, Busscher HJ, Herrmann A, van der Mei HC, Norde W. Pluronic-lysozyme conjugates as anti-adhesive and antibacterial biofunctional polymers for surface coating. Biomaterials 2011; 32:6333-6341.
31. Lunov O, Syrovets T, Büchele B, Jiang X, Röcker C, Tron K, Nienhaus GU, Walther P, Mailander V, Landfester K, Simmet T. The effect of carboxydextran-coated superparamagnetic iron oxide nanoparticles on C-jun N-terminal kinase-mediated apoptosis in human macrophages. Biomaterials 2010;31:5063-5071.
32. Seo YC, Choi WY, Lee CG, Cha SW, Kim YO, Kim JC, Drummen GPC, Lee HY. Enhanced immunomodulatory activity of gelatinencapsulated rubus coreanus miquel nanoparticles. Int J Mol Sci 2011;12:9031-9056.
33. Hayman AR, Cox TM. Purple acid phosphatase of the human macrophage and osteoclast-characterization, molecular properties, and crystallization of the recombinant di-iron-oxo protein secreted by baculovirus-infected insect cells. J Biol Chem 1994; 269:1294-1300.
34. Stöber W, Fink A, Bohn E. Controlled growth of monodisperse silica spheres in the micron size range. J Colloid Interface Sci 1968;26:62-69.
35. Pinkerneil P, Güldenhaupt J, Gerwert K, Kötting C. Surfaceattached polyhistidine-tag proteins characterized by FTIR difference spectroscopy. Chem Phys Chem 2012;13:2649-2653.
36. Barth A. The infrared absorption of amino acid side chains. Prog Biophys Mol Biol 2000;74:141-173.
37. Kong J, Yu S. Fourier transform infrared spectroscopic analysis of protein secondary structures. Acta Biochim Biophys Sin 2007;39: 549-559.
38. Zhang Q, Liu F, Nguyen KT, Ma X, Wang XJ, Xing BG, Zhao YL. Multifunctional mesoporous silica nanoparticles for cancertargeted and controlled drug delivery. Adv Fun Mater 2012;22: 5144-5156.
39. Creager MS, Jenkins JE, Thagard-Yeaman LA, Brooks AE, Jones JA, Lewis RV, Holland GP, Yarger JL. Solid-state NMR comparison of various spiders' dragline silk fiber. Biomacromolecules 2010;11:2039-2043.
40. Folkman J, Moscona A. Role of cell shape in growth control. Nature 1978; 273:345-349.
41. Lee S, Choi J, Shin S, Im YM, Song J, Kang SS, Nam TH, Webster TJ, Kim SH, Khang D. Analysis on migration and activation of live macrophages on transparent flat and nanostructured titanium. Acta Biomater 2011;7:2337-2344.
42. Yue H, Wei W, Yue ZG, Lv PP, Wang LY, Ma GH, Su ZG. Particle size affects the cellular response in macrophages. Eur J Pharm Sci 2010;41:650-657.
43. Chiou WF, Shum AYC, Peng CH, Chen CF, Chou CJ. Piperlactam S suppresses macrophage migration by impeding F-actin polymerization and filopodia extension. Eur J Pharmacol 2003;458:217-225.
44. Cai KY, Hou YH, Hu Y, Zhao L, Luo Z, Shi Y, Lai M, Yang WH, Liu P. Correlation of the cytotoxicity of TiO2 nanoparticles with different particle sizes on a sub-200-nm scale. Small 2011;7:3026-3031.
45. Kumari S, Mg S, Mayor S. Endocytosis unplugged: multiple ways to enter the cell. Cell Res 2010;20:256-275.
46. Luo Z, Cai KY, Hu Y, Li JH, Ding XW, Zhang BL, Xu DW, Yang WH, Liu P. Redox-responsive molecular nanoreservoirs for controlled intracellular anticancer drug delivery based on magnetic nanoparticles. Adv Mater 2012;24:431-435.
47. Orr G, Panther DJ, Phillips JL, Tarasevich BJ, Dohnalkova A, Hu DH, Teeguarden JG, Poundsl JG. Submicrometer and nanoscale inorganic particles exploit the actin machinery to be propelled along microvilli-like structures into alveolar cells. ACS Nano 2007;1:463-475.
48. Chung TH, Wu SH, Yao M, Lu CW, Lin YS, Hung Y, Mou CY, Chen YC, Huang DM. The effect of surface charge on the uptake and biological function of mesoporous silica nanoparticles in 3T3- L1 cells and human mesenchymal stem cells. Biomaterials 2007; 28:2959-2966.
49. Hirst SM, Karakoti AS, Tyler RD, Sriranganathan N, Seal S, Reilly CM. Anti-inflammatory properties of cerium oxide nanoparticles. Small 2009;5:2848-2856.
50. Park MV, Neigh AM, Vermeulen JP, de la Fonteyne LJ, Verharen HW, Briedé JJ, van Loveren H, de Jong WH. The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles. Biomaterials 2011;32:9810-9817.
51. Jeong YS, Oh WK, Kim S, Jang J. Cellular uptake, cytotoxicity, and ROS generation with silica/conducting polymer core/shell nanospheres. Biomaterials 2011;32:7217-7225.
52. Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Narimatsu S, Monobe Y, Imazawa T, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S. The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL- 1beta production, ROS production and endosomal rupture. Biomaterials 2010;31:6833-6842.
53. Fujisawa A, Kambe N, Saito M, Nishikomori R, Tanizaki H, Kanazawa N. Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells. Blood 2007;109:2903-2911.
54. Willingham SB, Bergstralh DT, O'Connor W, Morrison AC, Taxman DJ. Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/NLRP3 and ASC. Cell Host Microbe 2007;2:147-159.
55. Park EJ, Park K. Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro. Toxicol Lett 2009;184:18-25.
56. http://www.nursingtimes.net/nursing-practice/clinical-zones/haemat ology/routine-blood-tests/201124.article; http://www.webhealthcent re.com/HealthyLiving/lab-test-blood.aspx.
57. Darabos N, Hundric-Haspl Z, Haspl M, Markotic A, Darabos A, Moser C. Correlation between synovial fluid and serum IL-1b levels after ACL surgery - Preliminary report. Int Orthop 2009;33:413-418.
58. Sun A, Wang YP, Chia JS, Liu BY, Chiang CP. Treatment with levamisole and colchicine can result in a significant reduction of IL-6, IL-8 or TNF-a level in patients with mucocutaneous type of Behcet's disease. J Oral Pathol Med 2009;38:401-405.
59. Park JH, Gu L, von Maltzahn G, Ruoslahti E, Bhatia SN, Sailor MJ. Biodegradable luminescent porous silicon nanoparticles for in vivo applications. Nat Mater 2009;8:331-336.
60. Mitchell KKP, Liberman A, Kummel AC, Trogler WC. Iron(III)- doped, silica nanoshells: A biodegradable form of silica. J Am Chem Soc 2012;134: 13997-14003.