Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles by pH-sensitive nanovalves

Journal of the American Chemical Society

Volumn 132, Issue 36, 2010, Pages 12690-12697

  Meng, Huan ^a   Xue, Min ^a   Xia, Tian ^a   Zhao, Yan Li ^b   Tamanoi, Fuyuhiko ^a   Stoddart, J Fraser ^b   Zink, Jeffrey I ^a   Nel, Andre E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABIOTIC CONDITIONS; ANTICANCER DRUG; CARGO MOLECULES; CELL LINES; DELIVERY SYSTEMS; DOXORUBICIN; FUNCTIONALIZED; IN-CELL; IN-VITRO; MESOPOROUS SILICA NANOPARTICLES; NANOVALVES; PH SENSITIVE; SILICA NANOPARTICLES; SOLID SUPPORTS; SQUAMOUS CARCINOMA; SURFACE FUNCTIONALIZATION;

CELL CULTURE; NANOPARTICLES; SILICA;

CONTROLLED DRUG DELIVERY;

BETA CYCLODEXTRIN; DOXORUBICIN; NANOPARTICLE; SILICON DIOXIDE;

ACIDIFICATION; ARTICLE; CELL NUCLEUS; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENDOSOME; HUMAN; HUMAN CELL; IN VITRO STUDY; PH; POROSITY; SURFACE PROPERTY;

3T3-L1 CELLS; ANIMALS; ANTINEOPLASTIC AGENTS; BETA-CYCLODEXTRINS; CELL DEATH; CELL PROLIFERATION; CELLS, CULTURED; DRUG DELIVERY SYSTEMS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; NANOSTRUCTURES; PARTICLE SIZE; POROSITY; SILICON DIOXIDE; SURFACE PROPERTIES;

EID: 77956446557     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja104501a     Document Type: Article

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