Mesoporous silica nanoparticle-based double drug delivery system for glucose-responsive controlled release of insulin and cyclic AMP

Journal of the American Chemical Society

Volumn 131, Issue 24, 2009, Pages 8398-8400

  Zhao, Yannan ^a   Trewyn, Brian G ^a   Slowing, Igor I ^a   Lin, Victor S Y ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BORONIC ACID; CELL LINES; CELL VIABILITY; CELLULAR UPTAKE; CONTROLLED RELEASE; CYCLIC ADENOSINE MONOPHOSPHATE (CAMP); DRUG DELIVERY SYSTEM; EXTERIOR SURFACES; FLUORESCEIN ISOTHIOCYANATE; FLUORESCENCE CONFOCAL MICROSCOPY; FUNCTIONALIZED; GLUCONIC ACIDS; GLUCOSE-RESPONSIVE; IN-VITRO; MESO-PORES; MESOPOROUS SILICA NANOPARTICLES; PH CONDITION; UNIQUE FEATURES;

ACIDS; CARBOHYDRATES; CELL CULTURE; CELL MEMBRANES; CONFOCAL MICROSCOPY; CONTROLLED DRUG DELIVERY; FLOW CYTOMETRY; GLUCOSE; INSULIN; INTERNET PROTOCOLS; LABELS; MESOPOROUS MATERIALS; NANOPARTICLES; SILICA;

FETAL MONITORING;

CALCIUM CHANNEL; CYCLIC AMP; GLUCOSE; INSULIN; NANOPARTICLE; SILICON DIOXIDE NANOPARTICLE; UNCLASSIFIED DRUG; BORONIC ACID DERIVATIVE; DRUG DERIVATIVE; GLUCONIC ACID; SILICON DIOXIDE;

ACCURACY; ACIDITY; ARTICLE; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; COVALENT BOND; DOSE RESPONSE; DRUG DELIVERY SYSTEM; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INSULIN RELEASE; MOUSE; NONHUMAN; PARTICLE SIZE; PHAGOCYTOSIS; RAT; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION; ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG EFFECT; FIBROBLAST; HELA CELL; METABOLISM; METHODOLOGY; SYNTHESIS;

ANIMALS; BORONIC ACIDS; CYCLIC AMP; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; FIBROBLASTS; GLUCONATES; GLUCOSE; HELA CELLS; HUMANS; INSULIN; MICE; NANOPARTICLES; RATS; SILICON DIOXIDE;

EID: 67650521855     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja901831u     Document Type: Article

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