Piperlactam S suppresses macrophage migration by impeding F-actin polymerization and filopodia extension

European Journal of Pharmacology

Volumn 458, Issue 1-2, 2003, Pages 217-225

  Chiou, Wen Fei ^a   Shum, Andrew Yau Chik ^b   Peng, Chuen Huei ^b   Chen, Chieh Fu ^a,b   Chou, Cheng Jen ^a  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Cdc42; Complement 5a; F actin; Filopodia; Piperlactam S; RAW264.7 macrophage

Indexed keywords

ANTIBODY; CHEMOATTRACTANT; CYTOCHALASIN B; F ACTIN; LACTAM DERIVATIVE; PIPERLACTAM S; PROTEIN CDC42; RHO FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ASSAY; CELL FUNCTION; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FILOPODIUM; FLUORESCENCE; IN VITRO STUDY; LEUKOCYTE; MACROPHAGE MIGRATION; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN FAMILY; PROTEIN POLYMERIZATION; TIME;

ACTINS; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD11B; ANTIGENS, CD18; CDC42 GTP-BINDING PROTEIN; CELL LINE; CELL MOVEMENT; CHEMOTAXIS; COLCHICINE; COMPLEMENT C5A; CYTOCHALASIN B; DOSE-RESPONSE RELATIONSHIP, DRUG; LACTAMS; MACROPHAGES; MICE; MICE, INBRED ICR; PSEUDOPODIA;

EID: 12244275666     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02733-4     Document Type: Article

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