Submicrometer and nanoscale inorganic particles exploit the actin machinery to be propelled along microvilli-like structures into alveolar cells

ACS Nano

Volumn 1, Issue 5, 2007, Pages 463-475

  Orr, Galya ^a   Panther, David J ^a   Phillips, Jaclyn L ^a   Tarasevich, Barbara J ^a   Dohnalkova, Alice ^b   Hu, Dehong ^a   Teeguarden, Justin G ^a   Pounds, Joel G ^a  

^a PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

Author keywords

Alveolar; Amorphous silica; Epithelial cell; Microvilli; Nanoparticle

Indexed keywords

ACTIN FILAMENT; ADVERSE EFFECT; ALVEOLAR; AMORPHOUS SILICA; CELLULAR INTERACTION; CELLULAR RESPONSE; CHEMOKINES; EPITHELIAL CELLS; EXPERIMENTAL CONDITIONS; HUMAN EXPOSURES; IMMUNE RESPONSE; INORGANIC PARTICLES; MICROVILLI; NANO SCALE; NANOPARTICLE AGGREGATE; NANOSCALE PARTICLES; NEW MECHANISMS; POSITIVE SURFACE CHARGE; SUBMICROMETERS; TYPE II;

CELL MEMBRANES; CHARGED PARTICLES; CYTOLOGY; ENZYME ACTIVITY; MACHINERY; MATERIALS PROPERTIES; NANOPARTICLES; NANOSTRUCTURED MATERIALS; NANOTECHNOLOGY; SILICA; SURFACE PROPERTIES; SURFACES;

PROTEINS;

ACTIN; GREEN FLUORESCENT PROTEIN; INORGANIC COMPOUND; NANOPARTICLE; SILICON DIOXIDE;

ANIMAL; ARTICLE; CELL LINE; CELL MEMBRANE; CHEMISTRY; CYTOLOGY; EPITHELIUM CELL; LUNG ALVEOLUS; LYSOSOME; METABOLISM; MICROVILLUS; MOUSE; MOVEMENT (PHYSIOLOGY); PSEUDOPODIUM; SURFACE PROPERTY; ULTRASTRUCTURE;

ACTINS; ANIMALS; CELL LINE; CELL MEMBRANE; EPITHELIAL CELLS; GREEN FLUORESCENT PROTEINS; INORGANIC CHEMICALS; LYSOSOMES; MICE; MICROVILLI; MOVEMENT; NANOPARTICLES; PSEUDOPODIA; PULMONARY ALVEOLI; SILICON DIOXIDE; SURFACE PROPERTIES;

EID: 61549091522     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn700149r     Document Type: Article

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