Poly-L-lysine functionalized large pore cubic mesostructured silica nanoparticles as biocompatible carriers for gene delivery

ACS Nano

Volumn 6, Issue 3, 2012, Pages 2104-2117

  Hartono, Sandy B ^a   Gu, Wenyi ^a   Kleitz, Freddy ^c   Liu, Jian ^a   He, Lizhong ^a   Middelberg, Anton P J ^a   Yu, Chengzhong ^a   Lu, Gao Qing ^a   Qiao, Shi Zhang ^a,b  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c UNIVERSITÉ LAVAL   (Canada)

Author keywords

cellular uptake; gene delivery; mesoporous silica nanoparticles; poly L lysine; siRNA

Indexed keywords

CELLULAR UPTAKE; GENE DELIVERY; MESOPOROUS SILICA NANOPARTICLES; POLY-L-LYSINE; SIRNA;

BIOCOMPATIBILITY; CELLS; ENZYMES; MAGIC ANGLE SPINNING; NANOPARTICLES; NUCLEIC ACIDS; SILICA; THERMOGRAVIMETRIC ANALYSIS; X RAY PHOTOELECTRON SPECTROSCOPY;

GENE TRANSFER;

AMINE; BIOMATERIAL; DRUG CARRIER; NANOPARTICLE; POLYLYSINE; SILANE DERIVATIVE; SILICON DIOXIDE; SMALL INTERFERING RNA;

ADSORPTION; ARTICLE; CHEMISTRY; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; METHODOLOGY; NUCLEOTIDE SEQUENCE; ONCOGENE; POROSITY; SURFACE PROPERTY; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

ADSORPTION; AMINES; BASE SEQUENCE; BIOCOMPATIBLE MATERIALS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; DRUG CARRIERS; GENE SILENCING; HUMANS; NANOPARTICLES; ONCOGENES; POLYLYSINE; POROSITY; RNA, SMALL INTERFERING; SILANES; SILICON DIOXIDE; SURFACE PROPERTIES; TRANSFECTION;

EID: 84859145983     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn2039643     Document Type: Article

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