메뉴 건너뛰기




Volumn 31, Issue 20, 2014, Pages 1711-1720

Deficits in discrimination after experimental frontal brain injury are mediated by motivation and can be improved by nicotinamide administration

Author keywords

animal models; controlled cortical impact; operant learning

Indexed keywords

NICOTINAMIDE; VITAMIN B COMPLEX;

EID: 84908005771     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2014.3459     Document Type: Article
Times cited : (25)

References (50)
  • 2
    • 77954751786 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention National Center for Injury Prevention and Control Available at: Accessed July 30 2014
    • Centers for Disease Control and Prevention. National Center for Injury Prevention and Control. (2010) Traumatic Brain Injury in the United States. Available at: www.cdc.gov/traumaticbraininjury/pdf/blue-book.pdf. Accessed July 30, 2014
    • (2010) Traumatic Brain Injury in the United States
  • 7
    • 80051784028 scopus 로고    scopus 로고
    • Continuous nicotinamide administration improves behavioral recovery and reduces lesion size following bilateral frontal controlled cortical impact injury
    • Vonder Haar, C., Anderson, G.D., and Hoane, M.R. (2011). Continuous nicotinamide administration improves behavioral recovery and reduces lesion size following bilateral frontal controlled cortical impact injury. Behav. Brain Res. 224, 311-317
    • (2011) Behav. Brain Res , vol.224 , pp. 311-317
    • Vonder Haar, C.1    Anderson, G.D.2    Hoane, M.R.3
  • 8
    • 77953706144 scopus 로고    scopus 로고
    • Sustained delivery of nicotinamide limits cortical injury and improves functional recovery following traumatic brain injury
    • Goffus, A.M., Anderson, G.D., and Hoane, M. (2010). Sustained delivery of nicotinamide limits cortical injury and improves functional recovery following traumatic brain injury. Oxid. Med. Cell Longev. 3, 145-152
    • (2010) Oxid. Med. Cell Longev , vol.3 , pp. 145-152
    • Goffus, A.M.1    Anderson, G.D.2    Hoane, M.3
  • 9
    • 45049085934 scopus 로고    scopus 로고
    • Nicotinamide treatment induces behavioral recovery when administered up to 4 hours following cortical contusion injury in the rat
    • Hoane, M.R., Pierce, J.L., Holland, M.A., and Anderson, G.D. (2008). Nicotinamide treatment induces behavioral recovery when administered up to 4 hours following cortical contusion injury in the rat. Neuroscience 154, 861-868
    • (2008) Neuroscience , vol.154 , pp. 861-868
    • Hoane, M.R.1    Pierce, J.L.2    Holland, M.A.3    Anderson, G.D.4
  • 10
    • 33845230959 scopus 로고    scopus 로고
    • Nicotinamide treatment reduces behavioral impairments and provides cortical protection after fluid percussion injury in the rat
    • Hoane, M.R., Tan, A.A., Pierce, J.L., Anderson, G.D., and Smith, D.C. (2006). Nicotinamide treatment reduces behavioral impairments and provides cortical protection after fluid percussion injury in the rat. J. Neurotrauma 23, 1535-1548
    • (2006) J. Neurotrauma , vol.23 , pp. 1535-1548
    • Hoane, M.R.1    Tan, A.A.2    Pierce, J.L.3    Anderson, G.D.4    Smith, D.C.5
  • 11
    • 0344153780 scopus 로고    scopus 로고
    • Treatment with vitamin B3 improves functional recovery and reduces GFAP expression following traumatic brain injury in rats
    • Hoane, M.R., Akstulewicz, S.L., and Toppen, J. (2003). Treatment with vitamin B3 improves functional recovery and reduces GFAP expression following traumatic brain injury in rats. J. Neurotrauma 20, 1189-1199
    • (2003) J. Neurotrauma , vol.20 , pp. 1189-1199
    • Hoane, M.R.1    Akstulewicz, S.L.2    Toppen, J.3
  • 12
    • 70349683021 scopus 로고    scopus 로고
    • The vitamin nicotinamide: Translating nutrition into clinical care
    • Maiese, K., Chong, Z., Hou, J., and Shang, Y. (2009). The vitamin nicotinamide: Translating nutrition into clinical care. Molecules 14, 3446-3485
    • (2009) Molecules , vol.14 , pp. 3446-3485
    • Maiese, K.1    Chong, Z.2    Hou, J.3    Shang, Y.4
  • 13
    • 84908012900 scopus 로고    scopus 로고
    • The use of nicotinamide as a treatment for experimental traumatic brain injury and stroke: A review and evaluation
    • Vonder Haar, C., Peterson, T.C., Martens, K.M., and Hoane, M.R. (2013). The use of nicotinamide as a treatment for experimental traumatic brain injury and stroke: A review and evaluation. Clin. Pharmacol. Biopharm. S1, 005
    • (2013) Clin. Pharmacol. Biopharm , Issue.S1 , pp. 005
    • Vonder Haar, C.1    Peterson, T.C.2    Martens, K.M.3    Hoane, M.R.4
  • 14
    • 0141538207 scopus 로고    scopus 로고
    • Nicotinamide offers multiple protective mechanisms in stroke as a precursor to NAD+ , as a PARP inhibitor and by partial restoration of mitochondrial function
    • Klaidman, L.K., Morales, M., Kem, S., Yang, J., Chang, M.L., and Adams, J.D., Jr. (2003). Nicotinamide offers multiple protective mechanisms in stroke as a precursor to NAD+ , as a PARP inhibitor and by partial restoration of mitochondrial function. Pharmacology 69, 150-157
    • (2003) Pharmacology , vol.69 , pp. 150-157
    • Klaidman, L.K.1    Morales, M.2    Kem, S.3    Yang, J.4    Chang, M.L.5    Adams, J.D.6
  • 15
    • 79952774476 scopus 로고    scopus 로고
    • Preclinical efficacy testing in middle-Aged rats: Nicotinamide, a novel neuroprotectant, demonstrates diminished preclinical efficacy after controlled cortical impact
    • Swan, A.A., Chandrashekar, R., Beare, J., and Hoane, M.R. (2011). Preclinical efficacy testing in middle-Aged rats: nicotinamide, a novel neuroprotectant, demonstrates diminished preclinical efficacy after controlled cortical impact. J. Neurotrauma 28, 431-440
    • (2011) J. Neurotrauma , vol.28 , pp. 431-440
    • Swan, A.A.1    Chandrashekar, R.2    Beare, J.3    Hoane, M.R.4
  • 16
    • 84867506098 scopus 로고    scopus 로고
    • Comparing the predictive value of multiple cognitive, affective, and motor tasks after rodent traumatic brain injury
    • Zhao, Z., Loane, D.J., Murray II, M.G., Stoica, B.A., and Faden, A.I. (2012). Comparing the predictive value of multiple cognitive, affective, and motor tasks after rodent traumatic brain injury. J. Neurotrauma 29, 2475-2489
    • (2012) J. Neurotrauma , vol.29 , pp. 2475-2489
    • Zhao, Z.1    Loane, D.J.2    Murray, I.I.M.G.3    Stoica, B.A.4    Faden, A.I.5
  • 17
    • 84865616019 scopus 로고    scopus 로고
    • The effect of injury severity on behavior: A phenotypic study of cognitive and emotional deficits after mild, moderate, and severe controlled cortical impact injury in mice
    • Washington, P.M., Forcelli, P.A., Wilkins, T., Zapple, D.N., Parsadanian, M., and Burns, M.P. (2012). The effect of injury severity on behavior: a phenotypic study of cognitive and emotional deficits after mild, moderate, and severe controlled cortical impact injury in mice. J. Neurotrauma 29, 2283-2296
    • (2012) J. Neurotrauma , vol.29 , pp. 2283-2296
    • Washington, P.M.1    Forcelli, P.A.2    Wilkins, T.3    Zapple, D.N.4    Parsadanian, M.5    Burns, M.P.6
  • 18
    • 84867530848 scopus 로고    scopus 로고
    • A discrimination task used as a novel method of testing decision-making behavior following traumatic brain injury
    • Martens, K.M., Vonder Haar, C., Hutsell, B.A., and Hoane, M R. (2012). A discrimination task used as a novel method of testing decision-making behavior following traumatic brain injury. J. Neurotrauma 29, 2505-2512
    • (2012) J. Neurotrauma , vol.29 , pp. 2505-2512
    • Martens, K.M.1    Vonder Haar, C.2    Hutsell, B.A.3    Hoane, M.R.4
  • 19
    • 84875802473 scopus 로고    scopus 로고
    • The dig task: A simple scent discrimination reveals deficits following frontal brain damage
    • Martens, K.M., Vonder Haar, C., Hutsell, B.A., and Hoane, M.R. (2013). The dig task: a simple scent discrimination reveals deficits following frontal brain damage. J. Vis. Exp. 7, e50033
    • (2013) J. Vis. Exp , vol.7 , pp. e50033
    • Martens, K.M.1    Vonder Haar, C.2    Hutsell, B.A.3    Hoane, M.R.4
  • 20
    • 84893050522 scopus 로고    scopus 로고
    • Simple tone discriminations are disrupted following experimental frontal traumatic brain injury in rats
    • Vonder Haar, C., Smith, T.R., French, E.J., Martens, K.M., Jacobs, E.A., and Hoane, M.R. (2014). Simple tone discriminations are disrupted following experimental frontal traumatic brain injury in rats. Brain Inj. 28, 235-243
    • (2014) Brain Inj , vol.28 , pp. 235-243
    • Vonder Haar, C.1    Smith, T.R.2    French, E.J.3    Martens, K.M.4    Jacobs, E.A.5    Hoane, M.R.6
  • 21
    • 84900300946 scopus 로고    scopus 로고
    • Old dog, new tricks: The attentional set-shifting test as a novel cognitive behavioral task after controlled cortical impact injury
    • Bondi, C.O., Cheng, J.P., Tennant, H.M., Monaco, C.M., and Kline, A.E. (2014). Old dog, new tricks: The attentional set-shifting test as a novel cognitive behavioral task after controlled cortical impact injury. J. Neurotrauma 31, 926-937
    • (2014) J. Neurotrauma , vol.31 , pp. 926-937
    • Bondi, C.O.1    Cheng, J.P.2    Tennant, H.M.3    Monaco, C.M.4    Kline, A.E.5
  • 22
    • 0027999174 scopus 로고
    • Bilateral frontal cortical contusion in rats: Behavioral and anatomic consequences
    • Hoffman, S.W., Fülöp, Z., and Stein, D.G. (1994). Bilateral frontal cortical contusion in rats: Behavioral and anatomic consequences. J. Neurotrauma 11, 417-431
    • (1994) J. Neurotrauma , vol.11 , pp. 417-431
    • Hoffman, S.W.1    Fülöp, Z.2    Stein, D.G.3
  • 23
    • 0021744034 scopus 로고
    • Functions of the frontal cortex of the rat: A comparative review
    • Kolb, B. (1984). Functions of the frontal cortex of the rat: a comparative review. Brain Res. 320, 65-98
    • (1984) Brain Res , vol.320 , pp. 65-98
    • Kolb, B.1
  • 25
    • 0029863846 scopus 로고    scopus 로고
    • Self-Awareness of Deficits in Adults with Traumatic Brain Injury: How Best to Measure
    • Fleming, J.M., Strong, J., and Ashton, R. (1996). Self-Awareness of deficits in adults with traumatic brain injury: how best to measure? Brain Inj. 10, 1-15
    • (1996) Brain Inj , vol.10 , pp. 1-15
    • Fleming, J.M.1    Strong, J.2    Ashton, R.3
  • 26
    • 0036249031 scopus 로고    scopus 로고
    • Self-Awareness following traumatic brain injury and implications for rehabilitation
    • Port, A., Willmott, C., and Charlton, J. (2002). Self-Awareness following traumatic brain injury and implications for rehabilitation. Brain Inj. 16, 277-289
    • (2002) Brain Inj , vol.16 , pp. 277-289
    • Port, A.1    Willmott, C.2    Charlton, J.3
  • 27
    • 0030731499 scopus 로고    scopus 로고
    • Dissociable effects of cingulate and medial frontal cortex lesions on stimulusreward learning using a novel Pavlovian autoshaping procedure for the rat: Implications for the neurobiology of emotion
    • Bussey, T.J., Everitt, B.J., and Robbins, T.W. (1997). Dissociable effects of cingulate and medial frontal cortex lesions on stimulusreward learning using a novel Pavlovian autoshaping procedure for the rat: implications for the neurobiology of emotion. Behav. Neurosci. 111, 908-919
    • (1997) Behav. Neurosci , vol.111 , pp. 908-919
    • Bussey, T.J.1    Everitt, B.J.2    Robbins, T.W.3
  • 28
    • 0034212645 scopus 로고    scopus 로고
    • Medial frontal cortex mediates perceptual attentional set shifting in the rat
    • Birrell, J.M., and Brown, V.J. (2000). Medial frontal cortex mediates perceptual attentional set shifting in the rat. J. Neurosci. 20, 4320-4324
    • (2000) J. Neurosci , vol.20 , pp. 4320-4324
    • Birrell, J.M.1    Brown, V.J.2
  • 29
    • 0027501064 scopus 로고
    • Extinction of emotional learning: Contribution of medial prefrontal cortex
    • Morgan, M.A., Romanski, L.M., and LeDoux, J.E. (1993). Extinction of emotional learning: contribution of medial prefrontal cortex. Neurosci. Lett. 163, 109-113
    • (1993) Neurosci. Lett , vol.163 , pp. 109-113
    • Morgan, M.A.1    Romanski, L.M.2    Ledoux, J.E.3
  • 30
    • 0035707514 scopus 로고    scopus 로고
    • Place and response learning of rats in a Morris water maze: Differential effects of fimbria fornix and medial prefrontal cortex lesions
    • de Bruin, J.P., Moita, M.P., de Brabander, H.M., and Joosten, R.N. (2001). Place and response learning of rats in a Morris water maze: differential effects of fimbria fornix and medial prefrontal cortex lesions. Neurobiol. Learn. Mem. 75, 164-178
    • (2001) Neurobiol. Learn. Mem , vol.75 , pp. 164-178
    • De Bruin, J.P.1    Moita, M.P.2    De Brabander, H.M.3    Joosten, R.N.4
  • 32
    • 0027217279 scopus 로고
    • Traumatic brain injury produces impairments in long-Term and recent memory
    • Gorman, L.K., Shook, B.L., and Becker, D.P. (1993). Traumatic brain injury produces impairments in long-Term and recent memory. Brain Res. 614, 29-36
    • (1993) Brain Res , vol.614 , pp. 29-36
    • Gorman, L.K.1    Shook, B.L.2    Becker, D.P.3
  • 34
    • 79951770605 scopus 로고    scopus 로고
    • Cerebellar dentate nuclei lesions reduce motivation in appetitive operant conditioning and open field exploration
    • Bauer, D.J., Kerr, A.L., and Swain, R.A. (2011). Cerebellar dentate nuclei lesions reduce motivation in appetitive operant conditioning and open field exploration. Neurobiol. Learn. Mem. 95, 166-175
    • (2011) Neurobiol. Learn. Mem , vol.95 , pp. 166-175
    • Bauer, D.J.1    Kerr, A.L.2    Swain, R.A.3
  • 35
    • 0029980944 scopus 로고    scopus 로고
    • Progressive ratio schedules in drug self-Administration studies in rats: A method to evaluate reinforcing efficacy
    • Richardson, N.R., and Roberts, D.C. (1996). Progressive ratio schedules in drug self-Administration studies in rats: a method to evaluate reinforcing efficacy. J. Neurosci. Methods 66, 1-11
    • (1996) J. Neurosci. Methods , vol.66 , pp. 1-11
    • Richardson, N.R.1    Roberts, D.C.2
  • 36
    • 0032164653 scopus 로고    scopus 로고
    • Effects of step size and breakpoint criterion on progressive-ratio performance
    • Stafford, D., and Branch, M.N. (1998). Effects of step size and breakpoint criterion on progressive-ratio performance. J. Exp. Anal. Behav. 70, 123-138
    • (1998) J. Exp. Anal. Behav , vol.70 , pp. 123-138
    • Stafford, D.1    Branch, M.N.2
  • 37
    • 0024913248 scopus 로고
    • Effects of the n-methyl-d-Aspartate receptor blocker mk-801 on neurologic function after experimental brain injury
    • McIntosh, T.K., Vink, R., Soares, H., Hayes, R., and Simon, R. (1989). Effects of the N-methyl-D-Aspartate receptor blocker MK-801 on neurologic function after experimental brain injury. J. Neurotrauma 6, 247-259
    • (1989) J. Neurotrauma , vol.6 , pp. 247-259
    • McIntosh, T.K.1    Vink, R.2    Soares, H.3    Hayes, R.4    Simon, R.5
  • 42
    • 84870906088 scopus 로고    scopus 로고
    • A comparison of the effects of nicotinamide and progesterone on recovery of functional recovery of cognitive behavior following cortical contusion injury in the rat
    • Peterson, T.C., Anderson, G.D., Kantor, E.D., and Hoane, M.R. (2012). A comparison of the effects of nicotinamide and progesterone on recovery of functional recovery of cognitive behavior following cortical contusion injury in the rat. J. Neurotrauma 29, 2823-2830
    • (2012) J. Neurotrauma , vol.29 , pp. 2823-2830
    • Peterson, T.C.1    Anderson, G.D.2    Kantor, E.D.3    Hoane, M.R.4
  • 43
    • 0026567764 scopus 로고
    • A consideration of neural counting methods
    • Coggeshall, R.E. (1992). A consideration of neural counting methods. Trends Neurosci. 15, 9-13
    • (1992) Trends Neurosci , vol.15 , pp. 9-13
    • Coggeshall, R.E.1
  • 44
    • 0030828693 scopus 로고    scopus 로고
    • Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat
    • Bussey, T.J., Muir, J.L., Everitt, B.J., and Robbins, T.W. (1997). Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat. Behav. Neurosci. 111, 920-936
    • (1997) Behav. Neurosci , vol.111 , pp. 920-936
    • Bussey, T.J.1    Muir, J.L.2    Everitt, B.J.3    Robbins, T.W.4
  • 45
    • 2342650813 scopus 로고    scopus 로고
    • The neuropsychology of ventral prefrontal cortex: Decision-making and reversal learning
    • Clark, L., Cools, R., and Robbins, T.W. (2004). The neuropsychology of ventral prefrontal cortex: decision-making and reversal learning. Brain Cogn. 55, 41-53
    • (2004) Brain Cogn , vol.55 , pp. 41-53
    • Clark, L.1    Cools, R.2    Robbins, T.W.3
  • 47
    • 0036711827 scopus 로고    scopus 로고
    • Cognitive correlates of apathy in traumatic brain injury
    • Andersson, S., and Bergedalen, A.M. (2002). Cognitive correlates of apathy in traumatic brain injury. Cogn. Behav. Neurol. 15, 184-191
    • (2002) Cogn. Behav. Neurol , vol.15 , pp. 184-191
    • Andersson, S.1    Bergedalen, A.M.2
  • 48
    • 0242659432 scopus 로고    scopus 로고
    • Mood disorders following traumatic brain injury
    • Jorge, R., and Robinson, R.G. (2003). Mood disorders following traumatic brain injury. Int. Rev. Psychiatry 15, 317-327
    • (2003) Int. Rev. Psychiatry , vol.15 , pp. 317-327
    • Jorge, R.1    Robinson, R.G.2
  • 49
    • 0037010742 scopus 로고    scopus 로고
    • Motivational views of reinforcement: Implications for understanding the behavioral functions of nucleus accumbens dopamine
    • Salamone, J.D., and Correa, M. (2002). Motivational views of reinforcement: implications for understanding the behavioral functions of nucleus accumbens dopamine. Behav. Brain Res. 137, 3-25
    • (2002) Behav. Brain Res , vol.137 , pp. 3-25
    • Salamone, J.D.1    Correa, M.2
  • 50
    • 0033461157 scopus 로고    scopus 로고
    • The role of nucleus accumbens dopamine in motivated behavior: A unifying interpretation with special reference to reward-seeking
    • Ikemoto, S., and Panksepp, J. (1999). The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking. Brain Res. Brain Res. Rev. 31, 6-41
    • (1999) Brain Res. Brain Res. Rev , vol.31 , pp. 6-41
    • Ikemoto, S.1    Panksepp, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.