Preclinical efficacy testing in middle-aged rats: Nicotinamide, a novel neuroprotectant, demonstrates diminished preclinical efficacy after controlled cortical impact

Journal of Neurotrauma

Volumn 28, Issue 3, 2011, Pages 431-440

  Swan, Alicia A ^a   Chandrashekar, Rupa ^a   Beare, Jason ^a   Hoane, Michael R ^a  

^a SOUTHERN ILLINOIS UNIVERSITY   (United States)

Author keywords

aging; CCI; nicotinamide; recovery of function; therapy; traumatic brain injury

Indexed keywords

NICOTINAMIDE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN CONTUSION; COGNITION; CONTROLLED STUDY; DRUG EFFICACY; EDEMA; FEMALE; LESIONS AND DEFECTS; MALE; MOUSE; NONHUMAN; TRAUMATIC BRAIN INJURY;

AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; ASTROCYTES; BLOOD-BRAIN BARRIER; BRAIN EDEMA; BRAIN INJURIES; CEREBRAL CORTEX; COGNITION; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; MALE; MAZE LEARNING; MOTOR ACTIVITY; NIACINAMIDE; RATS; RATS, SPRAGUE-DAWLEY; RECOVERY OF FUNCTION; VITAMIN B COMPLEX;

EID: 79952774476     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2010.1519     Document Type: Article

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