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Volumn 13, Issue , 2014, Pages 1145-1162

Role of tight junctions in signal transduction: An update

Author keywords

Claudins; Human epithelial cells; Occludin; Signal transduction; Tight junctions

Indexed keywords

CLAUDIN; EPIDERMAL GROWTH FACTOR; ESTRADIOL; MITOGEN ACTIVATED PROTEIN KINASE; OCCLUDIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROGESTERONE; PROTEIN KINASE C; STRESS ACTIVATED PROTEIN KINASE; TRICELLULIN;

EID: 84907972519     PISSN: None     EISSN: 16112156     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (40)

References (132)
  • 3
    • 0030113804 scopus 로고    scopus 로고
    • Cell signalling: MAGUK magic
    • Anderson JM. Cell signalling: MAGUK magic. Curr Biol 1996;6:382–4.
    • (1996) Curr Biol , vol.6 , pp. 382-384
    • Anderson, J.M.1
  • 4
    • 0035914359 scopus 로고    scopus 로고
    • Protein kinase C regulates the phosphorylation and cellular localization of occludin
    • Andreeva AY, Krause E, Müller EC, Blasig IE, Utepbergenov DI. Protein kinase C regulates the phosphorylation and cellular localization of occludin. J Biol Chem 2001;276:38480-6.
    • (2001) J Biol Chem , vol.276 , pp. 38480-38486
    • Andreeva, A.Y.1    Krause, E.2    Müller, E.C.3    Blasig, I.E.4    Utepbergenov, D.I.5
  • 5
    • 1542777034 scopus 로고    scopus 로고
    • Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD
    • Baas AF, Kuipers J, van der Wel NN, Batlle E, Koerten HK, Peters PJ et al. Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD. Cell 2004;116:457-66.
    • (2004) Cell , vol.116 , pp. 457-466
    • Baas, A.F.1    Kuipers, J.2    van der Wel, N.N.3    Batlle, E.4    Koerten, H.K.5    Peters, P.J.6
  • 6
    • 63249132854 scopus 로고    scopus 로고
    • Tight junctions and the regulation of gene expression
    • Balda MS, Matter K. Tight junctions and the regulation of gene expression. Biochim Biophys Acta 2009; 1788:761–7.
    • (2009) Biochim Biophys Acta , vol.1788 , pp. 761-767
    • Balda, M.S.1    Matter, K.2
  • 7
    • 0029799520 scopus 로고    scopus 로고
    • Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein
    • Balda MS, Whitney JA, Flores C, González S, Cereijido M, Matter K. Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein. J Cell Biol 1996;134:1031-49.
    • (1996) J Cell Biol , vol.134 , pp. 1031-1049
    • Balda, M.S.1    Whitney, J.A.2    Flores, C.3    González, S.4    Cereijido, M.5    Matter, K.6
  • 8
    • 19444373410 scopus 로고    scopus 로고
    • theta Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: A novel mechanism for regulation of permeability
    • Banan A, Zhang LJ, Shaikh M, Fields JZ, Choudhary S, Forsyth CB et al. theta Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability. J Pharmacol Exp Ther 2005;313:962-82.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 962-982
    • Banan, A.1    Zhang, L.J.2    Shaikh, M.3    Fields, J.Z.4    Choudhary, S.5    Forsyth, C.B.6
  • 9
    • 0033789680 scopus 로고    scopus 로고
    • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
    • Batlle, E. 2000. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nat. Cell Biol. 2: 84–89.
    • (2000) Nat. Cell Biol , vol.2 , pp. 84-89
    • Batlle, E.1
  • 10
    • 47949094965 scopus 로고    scopus 로고
    • Integration of metabolism and inflammation by lipidactivated nuclear receptors
    • Bensinger SJ, Tontonoz P. Integration of metabolism and inflammation by lipidactivated nuclear receptors. Nature 2008;454:470–7.
    • (2008) Nature , vol.454 , pp. 470-477
    • Bensinger, S.J.1    Tontonoz, P.2
  • 11
    • 0031800762 scopus 로고    scopus 로고
    • Persistent activation of RelA by respiratory syncytial virus involves protein kinase C, underphosphorylated IB, and sequestration of protein phosphatase 2A by the viral phosphoprotein
    • Bitko V, Barik S. Persistent activation of RelA by respiratory syncytial virus involves protein kinase C, underphosphorylated IB, and sequestration of protein phosphatase 2A by the viral phosphoprotein. J Virol 1998;72:5610-8.
    • (1998) J Virol , vol.72 , pp. 5610-5618
    • Bitko, V.1    Barik, S.2
  • 12
    • 84865114404 scopus 로고    scopus 로고
    • Redistribution of adhering junctions in human endometrial epithelial cells during the implantation window of the menstrual cycle
    • Buck VU, Windoffer R, Leube RE, Classen-Linke I. Redistribution of adhering junctions in human endometrial epithelial cells during the implantation window of the menstrual cycle. Histochem Cell Biol 2012;137:777–90.
    • (2012) Histochem Cell Biol , vol.137 , pp. 777-790
    • Buck, V.U.1    Windoffer, R.2    Leube, R.E.3    Classen-Linke, I.4
  • 14
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • Cano A, Pérez-Moreno MA, Rodrigo I, Locascio A, Blanco MJ, del Barrio MG et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell  Biol 2000;2:76-83.
    • (2000) Nat Cell  Biol , vol.2 , pp. 76-83
    • Cano, A.1    Pérez-Moreno, M.A.2    Rodrigo, I.3    Locascio, A.4    Blanco, M.J.5    Del Barrio, M.G.6
  • 15
    • 0025997208 scopus 로고
    • Tumor necrosis factor alters cytoskeletal organization and barrier function of endothelial cells
    • Camussi G, Turello E, Bussolino F, Baglioni C. Tumor necrosis factor alters cytoskeletal organization and barrier function of endothelial cells. Int Arch Allergy Appl Immunol 1991;96:84–91.
    • (1991) Int Arch Allergy Appl Immunol , vol.96 , pp. 84-91
    • Camussi, G.1    Turello, E.2    Bussolino, F.3    Baglioni, C.4
  • 16
    • 70349253965 scopus 로고    scopus 로고
    • Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression
    • Carrozzino F, Pugnale P, Féraille E, Montesano R. Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression. Am J Physiol Cell Physiol 2009;297:C775–87.
    • (2009) Am J Physiol Cell Physiol , vol.297 , pp. C775-C787
    • Carrozzino, F.1    Pugnale, P.2    Féraille, E.3    Montesano, R.4
  • 17
    • 0031918158 scopus 로고    scopus 로고
    • Role of tight junctions in establishing and maintaining cell polarity
    • Cereijido M, Valdés J, Shoshani L, Contreras RG. Role of tight junctions in establishing and maintaining cell polarity. Ann Rev Physiol 1998;60:161–77.
    • (1998) Ann Rev Physiol , vol.60 , pp. 161-177
    • Cereijido, M.1    Valdés, J.2    Shoshani, L.3    Contreras, R.G.4
  • 18
    • 11144270589 scopus 로고    scopus 로고
    • Effects of transdifferentiation and EGF on claudin isoform expression in alveolar epithelial cells
    • Chen SP, Zhou B, Willis BC, Sandoval AJ, Liebler JM, Kim KJ et al. Effects of transdifferentiation and EGF on claudin isoform expression in alveolar epithelial cells. J Appl Physiol 2005;98:322–8.
    • (2005) J Appl Physiol , vol.98 , pp. 322-328
    • Chen, S.P.1    Zhou, B.2    Willis, B.C.3    Sandoval, A.J.4    Liebler, J.M.5    Kim, K.J.6
  • 19
    • 0033783241 scopus 로고    scopus 로고
    • Protein kinase C activation  leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets
    • Clarke H, Soler AP, Mullin JM. Protein kinase C activation  leads to dephosphorylation of occludin and tight junction permeability increase in LLC-PK1 epithelial cell sheets. J Cell Sci 2000;113:3187-96.
    • (2000) J Cell Sci , vol.113 , pp. 3187-3196
    • Clarke, H.1    Soler, A.P.2    Mullin, J.M.3
  • 20
    • 1442358790 scopus 로고    scopus 로고
    • Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton
    • Cohen D, Brennwald PJ, Rodriguez-Boulan E, Müsch A. Mammalian PAR-1 determines epithelial lumen polarity by organizing the microtubule cytoskeleton. J Cell Biol 2004;164:717-27.
    • (2004) J Cell Biol , vol.164 , pp. 717-727
    • Cohen, D.1    Brennwald, P.J.2    Rodriguez-Boulan, E.3    Müsch, A.4
  • 21
    • 34250346081 scopus 로고    scopus 로고
    • Par1b promotes hepatictype lumen polarity in Madin Darby canine kidney  cells via myosin II- and E-cadherin-dependent signaling
    • Cohen D, Tian Y, Müsch A. Par1b promotes hepatictype lumen polarity in Madin Darby canine kidney  cells via myosin II- and E-cadherin-dependent signaling. Mol Biol Cell 2007;18:2203-15.
    • (2007) Mol Biol Cell , vol.18 , pp. 2203-2215
    • Cohen, D.1    Tian, Y.2    Müsch, A.3
  • 22
    • 84856810398 scopus 로고    scopus 로고
    • Occludin: One protein, many forms
    • Cummins BM. Occludin: One protein, many forms. Mol Cell Biol 2012;32:242-50.
    • (2012) Mol Cell Biol , vol.32 , pp. 242-250
    • Cummins, B.M.1
  • 23
    • 84866289319 scopus 로고    scopus 로고
    • Progesterone promotes focal adhesion formation and migration in breast cancer cells through induction of protease-activated receptor- 1
    • Diaz J, Aranda E, Henriquez S, Quezada M, Espinoza E, Bravo ML et al. Progesterone promotes focal adhesion formation and migration in breast cancer cells through induction of protease-activated receptor- 1. J Endocrinol 2012;214:165–75.
    • (2012) J Endocrinol , vol.214 , pp. 165-175
    • Diaz, J.1    Aranda, E.2    Henriquez, S.3    Quezada, M.4    Espinoza, E.5    Bravo, M.L.6
  • 24
    • 0037847511 scopus 로고    scopus 로고
    • Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis
    • Dubuquoy L, Jansson EA, Deeb S, Rakotobe S, Karoui M, Colombel JF et al. Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis. Gastroenterology 2003;124:1265–76.
    • (2003) Gastroenterology , vol.124 , pp. 1265-1276
    • Dubuquoy, L.1    Jansson, E.A.2    Deeb, S.3    Rakotobe, S.4    Karoui, M.5    Colombel, J.F.6
  • 25
    • 0026759470 scopus 로고
    • Cellular variability in the development of tight junctions after activation of protein kinase C
    • Ellis B, Schneeberger EE, Rabito CA. Cellular variability in the development of tight junctions after activation of protein kinase C. Am J Physiol 1992;263: F293-300.
    • (1992) Am J Physiol , vol.263 , pp. F293-300
    • Ellis, B.1    Schneeberger, E.E.2    Rabito, C.A.3
  • 26
    • 42549158923 scopus 로고    scopus 로고
    • Protein kinase C: A target for therapy in pancreatic cancer
    • El-Rayes BF, Ali S, Philip PA, Sarkar FH. Protein kinase C: a target for therapy in pancreatic cancer. Pancreas 2008;36:346–52.
    • (2008) Pancreas , vol.36 , pp. 346-352
    • El-Rayes, B.F.1    Ali, S.2    Philip, P.A.3    Sarkar, F.H.4
  • 28
    • 84891494736 scopus 로고    scopus 로고
    • Humulone suppresses replication of respiratory syncytial virus and release of IL-8 and RANTES in normal human nasal epithelial cells
    • Fuchimoto J, Kojima T, Okabayashi T, Masaki T, Ogasawara N, Obata K et al. Humulone suppresses replication of respiratory syncytial virus and release of IL-8 and RANTES in normal human nasal epithelial cells. Med Mol Morphol 2013;46:203-9.
    • (2013) Med Mol Morphol , vol.46 , pp. 203-209
    • Fuchimoto, J.1    Kojima, T.2    Okabayashi, T.3    Masaki, T.4    Ogasawara, N.5    Obata, K.6
  • 29
    • 0034042544 scopus 로고    scopus 로고
    • Evidence of M cells as portals of entry for antigens in the nasopharyngeal lymphoid tissue of humans
    • Fujimura Y. Evidence of M cells as portals of entry for antigens in the nasopharyngeal lymphoid tissue of humans. Virchows Arch 2000;436:560-6.
    • (2000) Virchows Arch , vol.436 , pp. 560-566
    • Fujimura, Y.1
  • 30
    • 0034617463 scopus 로고    scopus 로고
    • Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein
    • Fujita K, Katahira J, Horiguchi Y, Sonoda N, Furuse M, Tsukita S. Clostridium perfringens enterotoxin binds to the second extracellular loop of claudin-3, a tight junction integral membrane protein. FEBS Letters 2000;476:258–61.
    • (2000) FEBS Letters , vol.476 , pp. 258-261
    • Fujita, K.1    Katahira, J.2    Horiguchi, Y.3    Sonoda, N.4    Furuse, M.5    Tsukita, S.6
  • 31
  • 32
    • 0027715358 scopus 로고
    • Breaking through the tight junction barrier
    • Gumbiner BM. Breaking through the tight junction barrier. J Cell Biol 1993;123:1631–3.
    • (1993) J Cell Biol , vol.123 , pp. 1631-1633
    • Gumbiner, B.M.1
  • 33
    • 63249098521 scopus 로고    scopus 로고
    • Tight junctions as targets of infectious agents
    • Guttman JA, Finlay BB. Tight junctions as targets of infectious agents. Biochim Biophys Acta 2009;1788: 832–41.
    • (2009) Biochim Biophys Acta , vol.1788 , pp. 832-841
    • Guttman, J.A.1    Finlay, B.B.2
  • 34
    • 79953756066 scopus 로고    scopus 로고
    • Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses
    • Hammad H, Lambrecht BN. Dendritic cells and airway epithelial cells at the interface between innate and adaptive immune responses. Allergy 2011;66: 579-87.
    • (2011) Allergy , vol.66 , pp. 579-587
    • Hammad, H.1    Lambrecht, B.N.2
  • 35
    • 33745610067 scopus 로고    scopus 로고
    • Rho kinase, myosin-II, and p42/44 MAPK control extracellular matrix-mediated apical bile canalicular lumen morphogenesis in HepG2 cells
    • Herrema H, Czajkowska D, Théard D, van der Wouden JM, Kalicharan D, Zolghadr B et al. Rho kinase, myosin-II, and p42/44 MAPK control extracellular matrix-mediated apical bile canalicular lumen morphogenesis in HepG2 cells. Mol Biol Cell 2006;17: 3291-303.
    • (2006) Mol Biol Cell , vol.17 , pp. 3291-3303
    • Herrema, H.1    Czajkowska, D.2    Théard, D.3    Van Der Wouden, J.M.4    Kalicharan, D.5    Zolghadr, B.6
  • 36
    • 0030751655 scopus 로고    scopus 로고
    • Occludin as a possible determinant of tight junction permeability in endothelial cells
    • Hirase T, Staddon JM, Saitou M, Ando-Akatsuka Y, Itoh M, Furuse M et al. Occludin as a possible determinant of tight junction permeability in endothelial cells. J Cell Sci 1997;110:1603-13.
    • (1997) J Cell Sci , vol.110 , pp. 1603-1613
    • Hirase, T.1    Staddon, J.M.2    Saitou, M.3    Ando-Akatsuka, Y.4    Itoh, M.5    Furuse, M.6
  • 37
    • 40949121542 scopus 로고    scopus 로고
    • The airway epithelium is central to the pathogenesis of asthma
    • Holgate ST. The airway epithelium is central to the pathogenesis of asthma. Allergol Int 2008;57:1-10.
    • (2008) Allergol Int , vol.57 , pp. 1-10
    • Holgate, S.T.1
  • 38
    • 70349329335 scopus 로고    scopus 로고
    • PPARalpha and PPARgamma attenuate HIVinduced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities
    • Huang W, Eum SY, András IE, Hennig B, Toborek M. PPARalpha and PPARgamma attenuate HIVinduced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities. FASEB J 2009;23:1596–606.
    • (2009) FASEB J , vol.23 , pp. 1596-1606
    • Huang, W.1    Eum, S.Y.2    András, I.E.3    Hennig, B.4    Toborek, M.5
  • 40
    • 79958744418 scopus 로고    scopus 로고
    • Epidermal growth factor increases clathrin-dependent endocytosis and degradation of claudin-2 protein in MDCK cells
    • Ikari A, Takiguchi A, Atomi K, Sugatani J. Epidermal growth factor increases clathrin-dependent endocytosis and degradation of claudin-2 protein in MDCK cells. J Cell Physiol 2011;226:2448–56.
    • (2011) J Cell Physiol , vol.226 , pp. 2448-2456
    • Ikari, A.1    Takiguchi, A.2    Atomi, K.3    Sugatani, J.4
  • 41
    • 0038106228 scopus 로고    scopus 로고
    • Regulation of tight junctions during the epitheliummesenchyme transition: Direct repression of the gene expression of claudins/occludin by Snail
    • Ikenouchi J, Matsuda M, Furuse M, Tsukita S. Regulation of tight junctions during the epitheliummesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail. J Cell Sci 2003;116:1959–67.
    • (2003) J Cell Sci , vol.116 , pp. 1959-1967
    • Ikenouchi, J.1    Matsuda, M.2    Furuse, M.3    Tsukita, S.4
  • 42
    • 29144533473 scopus 로고    scopus 로고
    • Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells
    • Ikenouchi J, Furuse M, Furuse K, Sasaki JH, Tsukita S, Tsukita S. Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells. J Cell Biol 2005;171:939–45.
    • (2005) J Cell Biol , vol.171 , pp. 939-945
    • Ikenouchi, J.1    Furuse, M.2    Furuse, K.3    Sasaki, J.H.4    Tsukita, S.5    Tsukita, S.6
  • 43
    • 34247508496 scopus 로고    scopus 로고
    • Oncostatin M induces upregulation of claudin-2 in rodent hepatocytes coinciding with changes in morphology and function of tight junctions
    • Imamura M, Kojima T, Lan M, Son S, Murata M, Osanai M et al. Oncostatin M induces upregulation of claudin-2 in rodent hepatocytes coinciding with changes in morphology and function of tight junctions. Exp Cell Res 2007;313:1951-62.
    • (2007) Exp Cell Res , vol.313 , pp. 1951-1962
    • Imamura, M.1    Kojima, T.2    Lan, M.3    Son, S.4    Murata, M.5    Osanai, M.6
  • 44
    • 80051519812 scopus 로고    scopus 로고
    • Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA-methylation in human pancreatic cancer cells
    • Ito T, Kojima T, Yamaguchi H, Kyuno D, Kimura Y, Imamura M et al. Transcriptional regulation of claudin-18 via specific protein kinase C signaling pathways and modification of DNA-methylation in human pancreatic cancer cells. J Cell Biochem 2011;112: 1761–72.
    • (2011) J Cell Biochem , vol.112 , pp. 1761-1772
    • Ito, T.1    Kojima, T.2    Yamaguchi, H.3    Kyuno, D.4    Kimura, Y.5    Imamura, M.6
  • 45
    • 58149110965 scopus 로고    scopus 로고
    • Ets transcription factors in intestinal morphogenesis, homeostasis and disease
    • Jedlicka P, Gutierrez-Hartmann A. Ets transcription factors in intestinal morphogenesis, homeostasis and disease. Histol Histopathol 2008;23:1417-24.
    • (2008) Histol Histopathol , vol.23 , pp. 1417-1424
    • Jedlicka, P.1    Gutierrez-Hartmann, A.2
  • 46
    • 38649104848 scopus 로고    scopus 로고
    • New markers of pancreatic cancer identified through differential gene expression analyses: Claudin 18 and annexin A8
    • Karanjawala ZE, Illei PB, Ashfaq R, Infante JR, Murphy K, Pandey A et al. New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8. Am J Surg Pathol 2008;32:188–96.
    • (2008) Am J Surg Pathol , vol.32 , pp. 188-196
    • Karanjawala, Z.E.1    Illei, P.B.2    Ashfaq, R.3    Infante, J.R.4    Murphy, K.5    Pandey, A.6
  • 47
    • 0030716491 scopus 로고    scopus 로고
    • Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo
    • Katahira J, Sugiyama H, Inoue N, Horiguchi Y, Matsuda M, Sugimoto N. Clostridium perfringens enterotoxin utilizes two structurally related membrane proteins as functional receptors in vivo. J Biol Chemi 1997;272:26652–8.
    • (1997) J Biol Chemi , vol.272 , pp. 26652-26658
    • Katahira, J.1    Sugiyama, H.2    Inoue, N.3    Horiguchi, Y.4    Matsuda, M.5    Sugimoto, N.6
  • 48
    • 79955024162 scopus 로고    scopus 로고
    • The airway antigen sampling system: Respiratory M cells as an alternative gateway for inhaled antigens
    • Kim DY, Sato A, Fukuyama S, Sagara H, Nagatake T, Kong IG et al. The airway antigen sampling system: respiratory M cells as an alternative gateway for inhaled antigens. J Immunol 2011;186:4253-62.
    • (2011) J Immunol , vol.186 , pp. 4253-4262
    • Kim, D.Y.1    Sato, A.2    Fukuyama, S.3    Sagara, H.4    Nagatake, T.5    Kong, I.G.6
  • 49
    • 33846003532 scopus 로고    scopus 로고
    • Expression of claudin7 is tightly associated with epithelial structures in synovial sarcomas and regulated by an Ets family transcription factor, ELF3
    • Kohno Y, Okamoto T, Ishibe T, Nagayama S, Shima Y, Nishijo K et al. Expression of claudin7 is tightly associated with epithelial structures in synovial sarcomas and regulated by an Ets family transcription factor, ELF3. J Biol Chem 2006;281:38941-50.
    • (2006) J Biol Chem , vol.281 , pp. 38941-38950
    • Kohno, Y.1    Okamoto, T.2    Ishibe, T.3    Nagayama, S.4    Shima, Y.5    Nishijo, K.6
  • 50
    • 47949119755 scopus 로고    scopus 로고
    • Protein kinase C enhances tight junction barrier function of human nasal epithelial cells in primary culture by transcriptional regulation
    • Koizumi J, Kojima T, Ogasawara N, Kamekura R, Kurose M, Go M et al. Protein kinase C enhances tight junction barrier function of human nasal epithelial cells in primary culture by transcriptional regulation. Mol Pharmacol 2008;74:432-42.
    • (2008) Mol Pharmacol , vol.74 , pp. 432-442
    • Koizumi, J.1    Kojima, T.2    Ogasawara, N.3    Kamekura, R.4    Kurose, M.5    Go, M.6
  • 51
    • 0142058534 scopus 로고    scopus 로고
    • Regulation of the blood-biliary barrier: Interaction between gap and tight junctions in hepatocytes
    • Kojima T, Yamamoto T, Murata M, Chiba H, Kokai Y, Sawada N. Regulation of the blood-biliary barrier: interaction between gap and tight junctions in hepatocytes. Med Electron Microsc 2003;36:157-64.
    • (2003) Med Electron Microsc , vol.36 , pp. 157-164
    • Kojima, T.1    Yamamoto, T.2    Murata, M.3    Chiba, H.4    Kokai, Y.5    Sawada, N.6
  • 52
    • 3142773675 scopus 로고    scopus 로고
    • Inhibition of MAP kinase activity moderates changes in expression and function of Cx32 but not claudin-1 during DNA synthesis in primary cultures of rat hepatocytes
    • Kojima T, Yamamoto T, Lan M, Murata M, Takano K, Go M et al. Inhibition of MAP kinase activity moderates changes in expression and function of Cx32 but not claudin-1 during DNA synthesis in primary cultures of rat hepatocytes. Med Electron Microsc 2004;37:101-13.
    • (2004) Med Electron Microsc , vol.37 , pp. 101-113
    • Kojima, T.1    Yamamoto, T.2    Lan, M.3    Murata, M.4    Takano, K.5    Go, M.6
  • 53
    • 40949123971 scopus 로고    scopus 로고
    • Transforming growth factor-beta induces epithelial to mesenchymal transition by down-regulation of claudin-1 expression and the fence function in adult rat hepatocytes
    • Kojima T, Takano K, Yamamoto T, Murata M, Son S, Imamura M et al. Transforming growth factor-beta induces epithelial to mesenchymal transition by down-regulation of claudin-1 expression and the fence function in adult rat hepatocytes. Liver Int 2008;28:534-45.
    • (2008) Liver Int , vol.28 , pp. 534-545
    • Kojima, T.1    Takano, K.2    Yamamoto, T.3    Murata, M.4    Son, S.5    Imamura, M.6
  • 54
    • 77957748045 scopus 로고    scopus 로고
    • Ninomiya T et al. c-Jun N-terminal kinase is largely involved in the regulation of tricellular tight junctions via tricellulin in human pancreatic duct epithelial cells
    • Kojima T, Fuchimoto J, Yamaguchi H, Ito T, Takasawa A, Ninomiya T et al. c-Jun N-terminal kinase is largely involved in the regulation of tricellular tight junctions via tricellulin in human pancreatic duct epithelial cells. J Cell Physiol 2010;225:720–33.
    • (2010) J Cell Physiol , vol.225 , pp. 720-733
    • Kojima, T.1    Fuchimoto, J.2    Yamaguchi, H.3    Ito, T.4    Takasawa, A.5
  • 55
    • 80051799359 scopus 로고    scopus 로고
    • Downregulation of tight junction associated MARVEL protein marvelD3 during epithelial mesenchymal transition in human pancreatic cancer cells
    • Kojima T, Takasawa A, Kyuno D, Ito T, Yamaguchi H, Hirata K et al. Downregulation of tight junction associated MARVEL protein marvelD3 during epithelial mesenchymal transition in human pancreatic cancer cells. Exp Cell Res 2011;317:2288–98.
    • (2011) Exp Cell Res , vol.317 , pp. 2288-2298
    • Kojima, T.1    Takasawa, A.2    Kyuno, D.3    Ito, T.4    Yamaguchi, H.5    Hirata, K.6
  • 56
    • 79960460826 scopus 로고    scopus 로고
    • Altered expression of claudin-1, claudin-7, and tricellulin regardless of human papilloma virus infection in human tonsillar squamous cell carcinoma
    • Kondoh A, Takano K, Kojima T, Ohkuni T, Kamekura R, Ogasawara N et al. Altered expression of claudin-1, claudin-7, and tricellulin regardless of human papilloma virus infection in human tonsillar squamous cell carcinoma. Acta Otolaryngol 2011;131: 861-8.
    • (2011) Acta Otolaryngol , vol.131 , pp. 861-868
    • Kondoh, A.1    Takano, K.2    Kojima, T.3    Ohkuni, T.4    Kamekura, R.5    Ogasawara, N.6
  • 58
    • 0842299393 scopus 로고    scopus 로고
    • Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated  by the p38 MAP kinase
    • Kubitz R, Sütfels G, Kühlkamp T, Kölling R, Häussinger D. Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated  by the p38 MAP kinase. Gastroenterology 2004; 126:541-53.
    • (2004) Gastroenterology , vol.126 , pp. 541-553
    • Kubitz, R.1    Sütfels, G.2    Kühlkamp, T.3    Kölling, R.4    Häussinger, D.5
  • 59
    • 34548724479 scopus 로고    scopus 로고
    • Induction of claudins in passaged hTERT-transfected human nasal epithelial cells with an extended life span
    • Kurose M, Kojima T, Koizumi J, Kamekura R, Ninomiya T, Murata M et al. Induction of claudins in passaged hTERT-transfected human nasal epithelial cells with an extended life span. Cell Tissue Res 2007;330:63-74.
    • (2007) Cell Tissue Res , vol.330 , pp. 63-74
    • Kurose, M.1    Kojima, T.2    Koizumi, J.3    Kamekura, R.4    Ninomiya, T.5    Murata, M.6
  • 60
    • 10344224515 scopus 로고    scopus 로고
    • Oncogenic Raf-1 regulates epithelial to mesenchymal transition via distinct signal transduction pathways in an immortalized mouse hepatic cell line
    • Lan M, Kojima T, Osanai M, Chiba H, Sawada N. Oncogenic Raf-1 regulates epithelial to mesenchymal transition via distinct signal transduction pathways in an immortalized mouse hepatic cell line. Carcinogenesis 2004;25:2385-95.
    • (2004) Carcinogenesis , vol.25 , pp. 2385-2395
    • Lan, M.1    Kojima, T.2    Osanai, M.3    Chiba, H.4    Sawada, N.5
  • 62
    • 70350554238 scopus 로고    scopus 로고
    • JNK phosphorylates beta-catenin and regulates adherens junctions
    • Lee MH, Koria P, Qu J, Andreadis ST. JNK phosphorylates beta-catenin and regulates adherens junctions. FASEB J 2009;23:3874–83.
    • (2009) FASEB J , vol.23 , pp. 3874-3883
    • Lee, M.H.1    Koria, P.2    Qu, J.3    Andreadis, S.T.4
  • 63
    • 34249989451 scopus 로고    scopus 로고
    • Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility
    • Leotlela PD, Wade MS, Duray PH, Rhode MJ, Brown HF, Rosenthal DT et al. Claudin-1 overexpression in melanoma is regulated by PKC and contributes to melanoma cell motility. Oncogene 2007;26:3846-56.
    • (2007) Oncogene , vol.26 , pp. 3846-3856
    • Leotlela, P.D.1    Wade, M.S.2    Duray, P.H.3    Rhode, M.J.4    Brown, H.F.5    Rosenthal, D.T.6
  • 64
    • 0031718808 scopus 로고    scopus 로고
    • Endometrial integrins and the establishment of uterine receptivity
    • Lessey BA. Endometrial integrins and the establishment of uterine receptivity. Hum Reprod 1998;13: 247–61.
    • (1998) Hum Reprod , vol.13 , pp. 247-261
    • Lessey, B.A.1
  • 65
    • 84856037260 scopus 로고    scopus 로고
    • Claudin-4-targeted therapy using Clostridium perfringens enterotoxin for prostate cancer
    • Maeda T, Murata M, Chiba H, Takasawa A, Tanaka S, Kojima T et al. Claudin-4-targeted therapy using Clostridium perfringens enterotoxin for prostate cancer. Prostate 2012;72:351-60.
    • (2012) Prostate , vol.72 , pp. 351-360
    • Maeda, T.1    Murata, M.2    Chiba, H.3    Takasawa, A.4    Tanaka, S.5    Kojima, T.6
  • 66
    • 2642614521 scopus 로고    scopus 로고
    • Junctional adhesion molecule, a novel member of the immunog lobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration
    • Martìn-Padura I, Lostaglio S, Schneemann M, Williams L, Romano M, Fruscella P et al. Junctional adhesion molecule, a novel member of the immunog lobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J Cell Biol 1998;142:117-27.
    • (1998) J Cell Biol , vol.142 , pp. 117-127
    • Martìn-Padura, I.1    Lostaglio, S.2    Schneemann, M.3    Williams, L.4    Romano, M.5    Fruscella, P.6
  • 67
    • 79959866726 scopus 로고    scopus 로고
    • A nuclear factor-B signaling pathway via protein kinase C regulates replication of respiratory syncytial virus in polarized normal human nasal epithelial cells
    • Masaki T, Kojima T, Okabayashi T, Ogasawara N, Ohkuni T, Obata K et al. A nuclear factor-B signaling pathway via protein kinase C regulates replication of respiratory syncytial virus in polarized normal human nasal epithelial cells. Mol Biol Cell 2011;22: 2144–56.
    • (2011) Mol Biol Cell , vol.22 , pp. 2144-2156
    • Masaki, T.1    Kojima, T.2    Okabayashi, T.3    Ogasawara, N.4    Ohkuni, T.5    Obata, K.6
  • 68
    • 77950122859 scopus 로고    scopus 로고
    • Negative regulation of the tight junction protein tricellulin by snail-induced epithelialmesenchymal transition in gastric carcinoma cells
    • Masuda R, Semba S, Mizuuchi E, Yanagihara K, Yokozaki H. Negative regulation of the tight junction protein tricellulin by snail-induced epithelialmesenchymal transition in gastric carcinoma cells. Pathobiology 2010;77:106–13.
    • (2010) Pathobiology , vol.77 , pp. 106-113
    • Masuda, R.1    Semba, S.2    Mizuuchi, E.3    Yanagihara, K.4    Yokozaki, H.5
  • 69
    • 79951830550 scopus 로고    scopus 로고
    • LSR defines cell corners for tricellular tight junction formation in epithelial cells
    • Masuda S, Oda Y, Sasaki H, Ikenouchi J, Higashi T, Akashi M et al. LSR defines cell corners for tricellular tight junction formation in epithelial cells. J Cell Sci 2011;124:548-55.
    • (2011) J Cell Sci , vol.124 , pp. 548-555
    • Masuda, S.1    Oda, Y.2    Sasaki, H.3    Ikenouchi, J.4    Higashi, T.5    Akashi, M.6
  • 72
    • 0034837388 scopus 로고    scopus 로고
    • Claudin-4: A new target for pancreatic cancer treatment using Clostridium perfringens enterotoxin
    • Michl P, Buchholz M, Rolke M, Kunsch S, Löhr M, McClane B et al. Claudin-4: a new target for pancreatic cancer treatment using Clostridium perfringens enterotoxin. Gastroenterology 2001;121:678-84.
    • (2001) Gastroenterology , vol.121 , pp. 678-684
    • Michl, P.1    Buchholz, M.2    Rolke, M.3    Kunsch, S.4    Löhr, M.5    McClane, B.6
  • 73
    • 0141885097 scopus 로고    scopus 로고
    • Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer
    • Michl P, Barth C, Buchholz M, Lerch MM, Rolke M, Holzmann KH et al. Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer. Cancer Res 2003;63:6265–71.
    • (2003) Cancer Res , vol.63 , pp. 6265-6271
    • Michl, P.1    Barth, C.2    Buchholz, M.3    Lerch, M.M.4    Rolke, M.5    Holzmann, K.H.6
  • 76
    • 0032500601 scopus 로고    scopus 로고
    • The role of phosphoinositide 3-kinase in taurocholate-induced trafficking of ATP-dependent canalicular transporters in rat liver
    • Misra S, Ujházy P, Gatmaitan Z, Varticovski L, Arias IM. The role of phosphoinositide 3-kinase in taurocholate-induced trafficking of ATP-dependent canalicular transporters in rat liver. J Biol Chem 1998; 273:26638-44.
    • (1998) J Biol Chem , vol.273 , pp. 26638-26644
    • Misra, S.1    Ujházy, P.2    Gatmaitan, Z.3    Varticovski, L.4    Arias, I.M.5
  • 77
    • 84861970173 scopus 로고    scopus 로고
    • Intracellular mediators of JAM-A-dependent epithelial barrier function
    • Monteiro AC, Parkos CA. Intracellular mediators of JAM-A-dependent epithelial barrier function. Ann N Y Acad Sci 2012;1257:115-24.
    • (2012) Ann N Y Acad Sci , vol.1257 , pp. 115-124
    • Monteiro, A.C.1    Parkos, C.A.2
  • 78
    • 25844492029 scopus 로고    scopus 로고
    • Down-regulation of survival signaling through MAPK and Akt in occludin-deficient mouse hepatocytes in vitro
    • Murata M, Kojima T, Yamamoto T, Go M, Takano K, Osanai M et al. Down-regulation of survival signaling through MAPK and Akt in occludin-deficient mouse hepatocytes in vitro. Exp Cell Res 2005;310:140–51.
    • (2005) Exp Cell Res , vol.310 , pp. 140-151
    • Murata, M.1    Kojima, T.2    Yamamoto, T.3    Go, M.4    Takano, K.5    Osanai, M.6
  • 80
    • 67650511409 scopus 로고    scopus 로고
    • c-Jun Nterminal kinase mediates disassembly of apical junctions in model intestinal epithelia
    • Naydenov NG, Hopkins AM, Ivanov AI. c-Jun Nterminal kinase mediates disassembly of apical junctions in model intestinal epithelia. Cell Cycle 2009;8: 2110–21.
    • (2009) Cell Cycle , vol.8 , pp. 2110-2121
    • Naydenov, N.G.1    Hopkins, A.M.2    Ivanov, A.I.3
  • 81
    • 0036513626 scopus 로고    scopus 로고
    • The snail superfamily of zinc-finger transcription factors
    • Nieto MA. The snail superfamily of zinc-finger transcription factors. Nat Rev Mol Cell Biol 2002;3: 155–66.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 155-166
    • Nieto, M.A.1
  • 82
    • 84896700990 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa elastase causes transient disruption of tight junctions and downregulation of PAR-2 in human nasal epithelial cells
    • Nomura K, Obata K, Keira T, Miyata R, Hirakawa S, Takano K et al. Pseudomonas aeruginosa elastase causes transient disruption of tight junctions and downregulation of PAR-2 in human nasal epithelial cells. Respir Res 2014;18:15-21.
    • (2014) Respir Res , vol.18 , pp. 15-21
    • Nomura, K.1    Obata, K.2    Keira, T.3    Miyata, R.4    Hirakawa, S.5    Takano, K.6
  • 83
    • 84884254240 scopus 로고    scopus 로고
    • Curcumin prevents replication of respiratory syncytial virus and the epithelial responses to it in human nasal epithelial cells
    • Obata K, Kojima T, Masaki T, Okabayashi T, Yokota S, Hirakawa S et al. Curcumin prevents replication of respiratory syncytial virus and the epithelial responses to it in human nasal epithelial cells. PLoS One 2013; 8:e70225.
    • (2013) PLoS One , vol.8
    • Obata, K.1    Kojima, T.2    Masaki, T.3    Okabayashi, T.4    Yokota, S.5    Hirakawa, S.6
  • 85
    • 84867402724 scopus 로고    scopus 로고
    • Epidermal growth factor modulates claudins and tight junctional functions in Histochem
    • Ogawa M, Kojima T, Someya M, Nomura K, Takasawa A, Murata M et al. Epidermal growth factor modulates claudins and tight junctional functions in Histochem. Cell Biol 2012;138:323-38.
    • (2012) Cell Biol , vol.138 , pp. 323-338
    • Ogawa, M.1    Kojima, T.2    Someya, M.3    Nomura, K.4    Takasawa, A.5    Murata, M.6
  • 86
    • 33749484749 scopus 로고    scopus 로고
    • Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosisassociated genes
    • Osanai M, Murata M, Nishikiori N, Chiba H, Kojima T, Sawada N. Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosisassociated genes. Cancer Res 2006;66:9125–33.
    • (2006) Cancer Res , vol.66 , pp. 9125-9133
    • Osanai, M.1    Murata, M.2    Nishikiori, N.3    Chiba, H.4    Kojima, T.5    Sawada, N.6
  • 87
    • 34247556499 scopus 로고    scopus 로고
    • The role of PPAR gamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction
    • Ponferrada A, Caso JR, Alou L, Colon A, Sevillano D, Moro MA et al. The role of PPAR gamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction. Gastroenterology 2007;132:1791–803.
    • (2007) Gastroenterology , vol.132 , pp. 1791-1803
    • Ponferrada, A.1    Caso, J.R.2    Alou, L.3    Colon, A.4    Sevillano, D.5    Moro, M.A.6
  • 88
    • 0030271724 scopus 로고    scopus 로고
    • Epidermal growth factor (EGF) increases the in vitro invasion, motility and adhesion interactions of the primary renal carcinoma cell line, A704
    • Price JT, Wilson HM, Haites NE. Epidermal growth factor (EGF) increases the in vitro invasion, motility and adhesion interactions of the primary renal carcinoma cell line, A704. Eur J Cancer 1996;32A:1977–82.
    • (1996) Eur J Cancer , vol.32A , pp. 1977-1982
    • Price, J.T.1    Wilson, H.M.2    Haites, N.E.3
  • 89
  • 90
    • 34249090814 scopus 로고    scopus 로고
    • Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity
    • Saadat I, Higashi H, Obuse C, Umeda M, Murata-Kamiya N, Saito Y et al. Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity. Nature 2007;447:330-3.
    • (2007) Nature , vol.447 , pp. 330-333
    • Saadat, I.1    Higashi, H.2    Obuse, C.3    Umeda, M.4    Murata-Kamiya, N.5    Saito, Y.6
  • 92
    • 59449083761 scopus 로고    scopus 로고
    • Claudin-18 splice variant 2 is a pancancer target suitable for therapeutic antibody development
    • Sahin U, Koslowski M, Dhaene K, Usener D, Brandenburg G, Seitz G et al. Claudin-18 splice variant 2 is a pancancer target suitable for therapeutic antibody development. Clin Cancer Res 2008;14:7624–34.
    • (2008) Clin Cancer Res , vol.14 , pp. 7624-7634
    • Sahin, U.1    Koslowski, M.2    Dhaene, K.3    Usener, D.4    Brandenburg, G.5    Seitz, G.6
  • 93
    • 0033396432 scopus 로고    scopus 로고
    • Bile acid secretion and direct targeting of mdr1-green fluorescent protein from Golgi to the canalicular membrane in polarized WIF-B cells
    • Sai Y, Nies AT, Arias IM. Bile acid secretion and direct targeting of mdr1-green fluorescent protein from Golgi to the canalicular membrane in polarized WIF-B cells. J Cell Sci 1999;112:4535-45.
    • (1999) J Cell Sci , vol.112 , pp. 4535-4545
    • Sai, Y.1    Nies, A.T.2    Arias, I.M.3
  • 94
    • 0032550221 scopus 로고    scopus 로고
    • Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions
    • Saitou M, Fujimoto K, Doi Y, Itoh M, Fujimoto T, Furuse M et al. Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J Cell Biol 1998;141:397-408.
    • (1998) J Cell Biol , vol.141 , pp. 397-408
    • Saitou, M.1    Fujimoto, K.2    Doi, Y.3    Itoh, M.4    Fujimoto, T.5    Furuse, M.6
  • 95
    • 0033635344 scopus 로고    scopus 로고
    • Complex phenotype of mice lacking occludin, a component of tight junction strands
    • Saitou M, Furuse M, Sasaki H, Schulzke JD, Fromm M, Takano H et al. Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell 2000;11: 4131-42.
    • (2000) Mol Biol Cell , vol.11 , pp. 4131-4142
    • Saitou, M.1    Furuse, M.2    Sasaki, H.3    Schulzke, J.D.4    Fromm, M.5    Takano, H.6
  • 96
    • 84873088762 scopus 로고    scopus 로고
    • Tight junction-related human diseases
    • Sawada N. Tight junction-related human diseases. Pathol Int 2013;63:1-12.
    • (2013) Pathol Int , vol.63 , pp. 1-12
    • Sawada, N.1
  • 98
  • 100
    • 34249668828 scopus 로고    scopus 로고
    • Protein phosphatases 2A and 1 interact with occludin and negatively regulate the assembly of tight junctions in the CACO-2 cell monolayer
    • Seth A, Sheth P, Elias BC, Rao R. Protein phosphatases 2A and 1 interact with occludin and negatively regulate the assembly of tight junctions in the CACO-2 cell monolayer. J Biol Chem 2007;282:11487-98.
    • (2007) J Biol Chem , vol.282 , pp. 11487-11498
    • Seth, A.1    Sheth, P.2    Elias, B.C.3    Rao, R.4
  • 101
    • 0942287209 scopus 로고    scopus 로고
    • Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells
    • Singh AB, Harris RC. Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells. J Biol Chem 2004;279: 3543–52.
    • (2004) J Biol Chem , vol.279 , pp. 3543-3552
    • Singh, A.B.1    Harris, R.C.2
  • 102
    • 36049034205 scopus 로고    scopus 로고
    • Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance
    • Singh AB, Sugimoto K, Dhawan P, Harris RC. Juxtacrine activation of EGFR regulates claudin expression and increases transepithelial resistance. Am J Physiol Cell Physiol 2007;293:C1660–8.
    • (2007) Am J Physiol Cell Physiol , vol.293 , pp. C1660-C1668
    • Singh, A.B.1    Sugimoto, K.2    Dhawan, P.3    Harris, R.C.4
  • 103
    • 0141749108 scopus 로고    scopus 로고
    • Distinct effects of protein kinase C on the barrier function at different developmental stages
    • Sjö A, Magnusson KE, Peterson KH. Distinct effects of protein kinase C on the barrier function at different developmental stages. Biosci Rep 2003;23:87-102.
    • (2003) Biosci Rep , vol.23 , pp. 87-102
    • Sjö, A.1    Magnusson, K.E.2    Peterson, K.H.3
  • 104
    • 84888301022 scopus 로고    scopus 로고
    • Regulation of tight junctions by sex hormones in normal human endometrial epithelial cells and uterus cancer cell line Sawano
    • Someya M, Kojima T, Ogawa M, Ninomiya T, Nomura K, Takasawa A et al. Regulation of tight junctions by sex hormones in normal human endometrial epithelial cells and uterus cancer cell line Sawano. Cell Tissue Res 2013;354:481-94.
    • (2013) Cell Tissue Res , vol.354 , pp. 481-494
    • Someya, M.1    Kojima, T.2    Ogawa, M.3    Ninomiya, T.4    Nomura, K.5    Takasawa, A.6
  • 105
    • 64949091718 scopus 로고    scopus 로고
    • Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells
    • Son S, Kojima T, Decaens C, Yamaguchi H, Ito T, Imamura M et al. Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells. Histochem Cell Biol 2009;131:411-24.
    • (2009) Histochem Cell Biol , vol.131 , pp. 411-424
    • Son, S.1    Kojima, T.2    Decaens, C.3    Yamaguchi, H.4    Ito, T.5    Imamura, M.6
  • 106
    • 0033523773 scopus 로고    scopus 로고
    • Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier
    • Sonoda N, Furuse M, Sasaki H, Yonemura S, Katahira J, Horiguchi Y et al. Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier. J Cell Biol 1999;147:195-204.
    • (1999) J Cell Biol , vol.147 , pp. 195-204
    • Sonoda, N.1    Furuse, M.2    Sasaki, H.3    Yonemura, S.4    Katahira, J.5    Horiguchi, Y.6
  • 107
    • 0030938632 scopus 로고    scopus 로고
    • Dendritic cells in the T-cell areas of lymphoid organs
    • Steinman RM, Pack M, Inaba K. Dendritic cells in the T-cell areas of lymphoid organs. Immunol Rev 1997; 156:25-37.
    • (1997) Immunol Rev , vol.156 , pp. 25-37
    • Steinman, R.M.1    Pack, M.2    Inaba, K.3
  • 108
    • 0029041046 scopus 로고
    • Regulated assembly of tight junctions by protein kinase C
    • Stuart RO, Nigam SK. Regulated assembly of tight junctions by protein kinase C. Proc Natl Acad Sci USA 1995;92:6072-6.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 6072-6076
    • Stuart, R.O.1    Nigam, S.K.2
  • 109
    • 0036120691 scopus 로고    scopus 로고
    • SS1 Helicobacter pylori disrupts the paracellular barrier of the gastric mucosa and leads to neutrophilic gastritis in mice
    • Suzuki K, Kokai Y, Sawada N, Takakuwa R, Kuwahara K, Isogai E et al. SS1 Helicobacter pylori disrupts the paracellular barrier of the gastric mucosa and leads to neutrophilic gastritis in mice. Virchows Arch 2002;440:318-24.
    • (2002) Virchows Arch , vol.440 , pp. 318-324
    • Suzuki, K.1    Kokai, Y.2    Sawada, N.3    Takakuwa, R.4    Kuwahara, K.5    Isogai, E.6
  • 110
    • 42549092329 scopus 로고    scopus 로고
    • Expression of tight junction proteins in epithelium including Ck20-positive M-like cells of human adenoids in vivo and in vitro
    • Takano K, Kojima T, Ogasawara N, Go M, Kikuchi S, Ninomiya T et al. Expression of tight junction proteins in epithelium including Ck20-positive M-like cells of human adenoids in vivo and in vitro. J Mol  Histol 2008;39:265-73.
    • (2008) J Mol  Histol , vol.39 , pp. 265-273
    • Takano, K.1    Kojima, T.2    Ogasawara, N.3    Go, M.4    Kikuchi, S.5    Ninomiya, T.6
  • 111
    • 0029990558 scopus 로고    scopus 로고
    • Adhesiveness of the apical surface of uterine epithelial cells: The role of junctional complex integrity
    • Thie M, Fuchs P, Butz S, Sieckmann F, Hoschützky H et al. Adhesiveness of the apical surface of uterine epithelial cells: the role of junctional complex integrity. Eur J Cell Biol 1996;70:221–32.
    • (1996) Eur J Cell Biol , vol.70 , pp. 221-232
    • Thie, M.1    Fuchs, P.2    Butz, S.3    Sieckmann, F.4    Hoschützky, H.5
  • 112
    • 4143128359 scopus 로고    scopus 로고
    • Epidermal growth factor receptor expression in human pancreatic cancer: Significance for liver metastasis
    • Tobita K, Kijima H, Dowaki S, Kashiwagi H, Ohtani Y, Oida Y et al. Epidermal growth factor receptor expression in human pancreatic cancer: significance for liver metastasis. Int J Mol Med 2003;11:305–9.
    • (2003) Int J Mol Med , vol.11 , pp. 305-309
    • Tobita, K.1    Kijima, H.2    Dowaki, S.3    Kashiwagi, H.4    Ohtani, Y.5    Oida, Y.6
  • 113
    • 0033004247 scopus 로고    scopus 로고
    • Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins
    • Tsukamoto T, Nigam SK. Role of tyrosine phosphorylation in the reassembly of occludin and other tight junction proteins. Am J Physiol 1999;276:F737-50.
    • (1999) Am J Physiol , vol.276 , pp. F737-F750
    • Tsukamoto, T.1    Nigam, S.K.2
  • 115
    • 9844246984 scopus 로고    scopus 로고
    • A novel epithelial-expressed ETS gene, ELF3: Human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer
    • Tymms MJ, Ng AY, Thomas RS, Schutte BC, Zhou J, Eyre HJ et al. A novel epithelial-expressed ETS gene, ELF3: human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer. Oncogene 1997;15: 2449-62.
    • (1997) Oncogene , vol.15 , pp. 2449-2462
    • Tymms, M.J.1    Ng, A.Y.2    Thomas, R.S.3    Schutte, B.C.4    Zhou, J.5    Eyre, H.J.6
  • 116
    • 33747155076 scopus 로고    scopus 로고
    • ZO-1 and ZO-2 independently determine where claudins are polymerized in tight junction strand formation
    • Umeda K, Ikenouchi J, Katahira-Tayama S, Furuse K, Sasaki H, Nakayama M et al. ZO-1 and ZO-2 independently determine where claudins are polymerized in tight junction strand formation. Cell 2006;126: 741–54.
    • (2006) Cell , vol.126 , pp. 741-754
    • Umeda, K.1    Ikenouchi, J.2    Katahira-Tayama, S.3    Furuse, K.4    Sasaki, H.5    Nakayama, M.6
  • 117
    • 0022748005 scopus 로고
    • The function of tight junctions  in maintaining differences in lipid composition  between the apical and the basolateral cell surface domains of MDCK cells
    • van Meer G, Simons K. The function of tight junctions  in maintaining differences in lipid composition  between the apical and the basolateral cell surface domains of MDCK cells. EMBO J 1986;5:1455–64.
    • (1986) EMBO J , vol.5 , pp. 1455-1464
    • Van Meer, G.1    Simons, K.2
  • 119
    • 20144376277 scopus 로고    scopus 로고
    • Influence of protein kinase C on transcription of the tight junction elements ZO-1 and occludin
    • Weiler F, Marbe T, Scheppach W, Schauber J. Influence of protein kinase C on transcription of the tight junction elements ZO-1 and occludin. J Cell Physiol 2005;204:83-6.
    • (2005) J Cell Physiol , vol.204 , pp. 83-86
    • Weiler, F.1    Marbe, T.2    Scheppach, W.3    Schauber, J.4
  • 120
    • 33646573080 scopus 로고    scopus 로고
    • Activation of protein kinase C ˙by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells
    • Xie Z, Dong Y, Zhang M, Cui MZ, Cohen RA, Riek U et al. Activation of protein kinase C ˙by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells. J Biol Chem 2006;281:6366-75.
    • (2006) J Biol Chem , vol.281 , pp. 6366-6375
    • Xie, Z.1    Dong, Y.2    Zhang, M.3    Cui, M.Z.4    Cohen, R.A.5    Riek, U.6
  • 121
    • 77957255799 scopus 로고    scopus 로고
    • Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells
    • Yamaguchi H, Kojima T, Ito T, Kimura Y, Imamura M, Son S et al. Transcriptional control of tight junction proteins via a protein kinase C signal pathway in human telomerase reverse transcriptase-transfected human pancreatic duct epithelial cells. Am J Pathol 2010;177:698-712.
    • (2010) Am J Pathol , vol.177 , pp. 698-712
    • Yamaguchi, H.1    Kojima, T.2    Ito, T.3    Kimura, Y.4    Imamura, M.5    Son, S.6
  • 122
    • 4444335486 scopus 로고    scopus 로고
    • IL-1beta regulates expression of Cx32, occludin, and claudin-2 of rat hepatocytes via distinct signal transduction pathways
    • Yamamoto T, Kojima T, Murata M, Takano K, Go M, Chiba H et al. IL-1beta regulates expression of Cx32, occludin, and claudin-2 of rat hepatocytes via distinct signal transduction pathways. Exp Cell Res 2004; 299:427-41.
    • (2004) Exp Cell Res , vol.299 , pp. 427-441
    • Yamamoto, T.1    Kojima, T.2    Murata, M.3    Takano, K.4    Go, M.5    Chiba, H.6
  • 123
    • 17144382084 scopus 로고    scopus 로고
    • p38 MAP-kinase regulates function of gap and tight junctions during regeneration of rat hepatocytes
    • Yamamoto T, Kojima T, Murata M, Takano K, Go M, Hatakeyama N et al. p38 MAP-kinase regulates function of gap and tight junctions during regeneration of rat hepatocytes. J Hepatol 2005;42:707-18.
    • (2005) J Hepatol , vol.42 , pp. 707-718
    • Yamamoto, T.1    Kojima, T.2    Murata, M.3    Takano, K.4    Go, M.5    Hatakeyama, N.6
  • 124
    • 0037438711 scopus 로고    scopus 로고
    • Microbial colonization drives lymphocyte accumulation and differentiation in the follicle-associated epithelium of Peyer's patches
    • Yamanaka T, Helgeland L, Farstad IN, Fukushima H, Midtvedt T, Brandtzaeg P. Microbial colonization drives lymphocyte accumulation and differentiation in the follicle-associated epithelium of Peyer's patches. J Immunol 2003;170:816-22.
    • (2003) J Immunol , vol.170 , pp. 816-822
    • Yamanaka, T.1    Helgeland, L.2    Farstad, I.N.3    Fukushima, H.4    Midtvedt, T.5    Brandtzaeg, P.6
  • 125
    • 38649126916 scopus 로고    scopus 로고
    • Transcriptional activation of the human claudin-18 gene promoter through two AP-1 motifs in PMA-stimulated MKN45 gastric cancer cells
    • Yano K, Imaeda T, Niimi T. Transcriptional activation of the human claudin-18 gene promoter through two AP-1 motifs in PMA-stimulated MKN45 gastric cancer cells. Am J Physiol Gastrointest Liver Physiol 2008;294:G336–43.
    • (2008) Am J Physiol Gastrointest Liver Physiol , vol.294 , pp. G336-G343
    • Yano, K.1    Imaeda, T.2    Niimi, T.3
  • 126
    • 76249104369 scopus 로고    scopus 로고
    • Rhinovirus infection-induced alteration of tight junction and adherens junction components in human nasal epithelial cells
    • Yeo NK, Jang YJ. Rhinovirus infection-induced alteration of tight junction and adherens junction components in human nasal epithelial cells. Laryngoscope 2010;120:346–52.
    • (2010) Laryngoscope , vol.120 , pp. 346-352
    • Yeo, N.K.1    Jang, Y.J.2
  • 127
    • 0142074303 scopus 로고    scopus 로고
    • Serially passaged human nasal epithelial cell monolayer for in vitro drug transport studies
    • Yoo JW, Kim YS, Lee SH, Lee MK, Roh HJ, Jhun BH et al. Serially passaged human nasal epithelial cell monolayer for in vitro drug transport studies. Pharm Res 2003;20:1690-6.
    • (2003) Pharm Res , vol.20 , pp. 1690-1696
    • Yoo, J.W.1    Kim, Y.S.2    Lee, S.H.3    Lee, M.K.4    Roh, H.J.5    Jhun, B.H.6
  • 128
    • 79951669627 scopus 로고    scopus 로고
    • virus entry into hepatocytes: Molecular mechanisms and targets for antiviral therapies
    • Zeisel MB, Fofana I, Fafi-Kremer S, Baumert TF. Hepatitis C virus entry into hepatocytes: Molecular mechanisms and targets for antiviral therapies. J Hepatol 2011;54:566–76.
    • (2011) J Hepatol , vol.54 , pp. 566-576
    • Zeisel, M.B.1    Fofana, I.2    Fafi-Kremer, S.3    Baumert, T.F.4    Hepatitis, C.5
  • 130
    • 33751204464 scopus 로고    scopus 로고
    • AMP-activated protein kinase regulates the assembly of epithelial tight junctions
    • Zhang L, Li J, Young LH, Caplan MJ. AMP-activated protein kinase regulates the assembly of epithelial tight junctions. Proc Natl Acad Sci USA 2006;103: 17272-7.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17272-17277
    • Zhang, L.1    Li, J.2    Young, L.H.3    Caplan, M.J.4
  • 131
    • 33846521353 scopus 로고    scopus 로고
    • Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase
    • Zheng B, Cantley LC. Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase. Proc Natl Acad Sci USA 2007;104: 819-22.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 819-822
    • Zheng, B.1    Cantley, L.C.2
  • 132
    • 84860389234 scopus 로고    scopus 로고
    • Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT-like phenotype change and MMP-9-mediated degradation of E-Cadherin
    • Zuo JH, Zhu W, Li MY, Li XH, Yi H, Zeng GQ et al. Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT-like phenotype change and MMP-9-mediated degradation of E-Cadherin. J Cell Biochem 2011;112: 2508–17.
    • (2011) J Cell Biochem , vol.112 , pp. 2508-2517
    • Zuo, J.H.1    Zhu, W.2    Li, M.Y.3    Li, X.H.4    Yi, H.5    Zeng, G.Q.6


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