PPARα and PPARγ attenuate HIV-induced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities

FASEB Journal

Volumn 23, Issue 5, 2009, Pages 1596-1606

  Huang, Wen ^a   Sung, Yong Eum ^a   András, Ibolya E ^a   Hennig, Bernhard ^b   Toborek, Michal ^a,c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

Blood brain barrier; Brain endothelial cells; Human immunodeficiency virus 1; Peroxisome proliferator activated receptor

Indexed keywords

GELATINASE A; GELATINASE B; JUNCTIONAL ADHESION MOLECULE A; MEMBRANE PROTEIN; OCCLUDIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEASOME; UNCLASSIFIED DRUG; ZONULA OCCLUDENS 1; CELL ADHESION MOLECULE; IMMUNOGLOBULIN; JUNCTIONAL ADHESION MOLECULE A , HUMAN; JUNCTIONAL ADHESION MOLECULE-A , HUMAN; PEPTIDYLGLUTAMYLPEPTIDE HYDROLASE; PHOSPHOPROTEIN; PROTEIN ZO1; PROTEINASE; ZONULA OCCLUDENS-1 PROTEIN;

ARTICLE; BLOOD BRAIN BARRIER; CELL MEMBRANE PERMEABILITY; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MICROVASCULATURE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TIGHT JUNCTION; BIOSYNTHESIS; BRAIN; CELL LINE; COCULTURE; GENE SILENCING; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

BLOOD-BRAIN BARRIER; BRAIN; CELL ADHESION MOLECULES; CELL LINE; COCULTURE TECHNIQUES; ENDOPEPTIDASES; ENDOTHELIAL CELLS; GENE SILENCING; HIV-1; HUMANS; IMMUNOGLOBULINS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MEMBRANE PROTEINS; PHOSPHOPROTEINS; PPAR ALPHA; PPAR GAMMA; PROTEASOME ENDOPEPTIDASE COMPLEX; TIGHT JUNCTIONS;

EID: 70349329335     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-121624     Document Type: Article

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