Curcumin Prevents Replication of Respiratory Syncytial Virus and the Epithelial Responses to It in Human Nasal Epithelial Cells

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Obata, Kazufumi ^a   Kojima, Takashi ^a   Masaki, Tomoyuki ^a   Okabayashi, Tamaki ^b   Yokota, Shinichi ^a   Hirakawa, Satoshi ^a   Nomura, Kazuaki ^a   Takasawa, Akira ^a   Murata, Masaki ^a   Tanaka, Satoshi ^a   Fuchimoto, Jun ^a   Fujii, Nobuhiro ^a   Tsutsumi, Hiroyuki ^a   Himi, Tetsuo ^a   Sawada, Norimasa ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CURCUMIN; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; IMD 0354; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INITIATION FACTOR 2ALPHA; PROTEASOME; PROTEIN SERINE THREONINE KINASE INHIBITOR; SALUBRINAL; TIGHT JUNCTION PROTEIN; UNCLASSIFIED DRUG; VIRUS RNA;

ARTICLE; CELL DIVISION; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; NOSE MUCOSA; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RESPIRATORY SYNCYTIAL VIRUS INFECTION; TREATMENT RESPONSE; VIRUS RELEASE; VIRUS REPLICATION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHILD, PRESCHOOL; CINNAMATES; CURCUMIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ENZYME INHIBITORS; EPITHELIAL CELLS; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INFANT; LEUPEPTINS; NASAL MUCOSA; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRIMARY CELL CULTURE; PROTEASOME ENDOPEPTIDASE COMPLEX; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; SIGNAL TRANSDUCTION; THIOUREA; VIRUS RELEASE; VIRUS REPLICATION;

EID: 84884254240     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070225     Document Type: Article

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