Serially Passaged Human Nasal Epithelial Cell Monolayer for in Vitro Drug Transport Studies

Pharmaceutical Research

Volumn 20, Issue 10, 2003, Pages 1690-1696

  Yoo, Jin Wook ^a   Kim, You Sun ^b   Lee, Sun Hee ^a   Lee, Min Ki ^b   Roh, Hwan Jung ^b   Jhun, Byung Hak ^a   Lee, Chi Ho ^a   Kim, Dae Duk ^a,c  

^a Pusan National University   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Budesonide; Human nasal epithelial cell culture; In vitro drug transport; Mannitol; Serially passaged culture; Tight junction; Transepithelial electrical resistance

Indexed keywords

ACTIN; BUDESONIDE; CARBON 14; MANNITOL;

ACTIN FILAMENT; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL ULTRASTRUCTURE; CILIARY BODY EPITHELIUM; CONTROLLED STUDY; DRUG PENETRATION; DRUG TRANSPORT; EVALUATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; MICROVILLUS; MONOLAYER CULTURE; NOSE MUCOSA; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; TIGHT JUNCTION; TRANSMISSION ELECTRON MICROSCOPY;

BIOLOGICAL TRANSPORT; BUDESONIDE; CARBON RADIOISOTOPES; CELLS, CULTURED; ELECTRIC CONDUCTIVITY; EPITHELIAL CELLS; HUMANS; MANNITOL; MICROSCOPY, ELECTRON; NASAL MUCOSA; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS;

EID: 0142074303     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026112107100     Document Type: Article

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