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Volumn 6, Issue 1, 2014, Pages

The involvement of aldosterone on vascular insulin resistance: Implications in obesity and type 2 diabetes

Author keywords

Aldosterone; Cardiovascular disease; Insulin resistance; Vascular dysfunction

Indexed keywords

ALDOSTERONE;

EID: 84907972331     PISSN: None     EISSN: 17585996     Source Type: Journal    
DOI: 10.1186/1758-5996-6-90     Document Type: Article
Times cited : (38)

References (86)
  • 2
    • 84893869723 scopus 로고    scopus 로고
    • Aldosterone synthase inhibitors in cardiovascular and renal diseases
    • 24493871
    • Aldosterone synthase inhibitors in cardiovascular and renal diseases. Namsolleck P, Unger T, Nephrol Dial Transplant 2014 29 suppl1 62 i68 24493871
    • (2014) Nephrol Dial Transplant , vol.29 , pp. 962-i68
    • Namsolleck, P.1    Unger, T.2
  • 4
    • 31944432423 scopus 로고    scopus 로고
    • Mechanisms of mineralocorticoid action
    • 16286565
    • Mechanisms of mineralocorticoid action. Fuller PJ, Young MJ, Hypertension 2005 46 6 1227 1235 10.1161/01.HYP.0000193502.77417.17 16286565
    • (2005) Hypertension , vol.46 , Issue.6 , pp. 1227-1235
    • Fuller, P.J.1    Young, M.J.2
  • 6
    • 79953235261 scopus 로고    scopus 로고
    • GPR30 expression is required for the mineralocorticoid receptor-independent rapid vascular effects of aldosterone
    • 21242460
    • GPR30 expression is required for the mineralocorticoid receptor-independent rapid vascular effects of aldosterone. Gros R, Ding Q, Sklar LA, Prossnitz EE, Arterburn JB, Chorazyczewski J, Feldman RD, Hypertension 2011 57 442 451 10.1161/HYPERTENSIONAHA.110.161653 21242460
    • (2011) Hypertension , vol.57 , pp. 442-451
    • Gros, R.1    Ding, Q.2    Sklar, L.A.3    Prossnitz, E.E.4    Arterburn, J.B.5    Chorazyczewski, J.6    Feldman, R.D.7
  • 7
    • 80051964047 scopus 로고    scopus 로고
    • Vascular proinflammatory responses by aldosterone are mediated via c-Src trafficking to cholesterol-rich microdomains: Role of PDGFR
    • Vascular proinflammatory responses by aldosterone are mediated via c-Src trafficking to cholesterol-rich microdomains: role of PDGFR. Callera GE, Yogi A, Briones AM, Montezano AC, He Y, Tostes RC, Schiffrin EL, Touyz RM, Cardiovasc Res 2011 1 suppl 4 720 731
    • (2011) Cardiovasc Res , vol.1 , pp. 720-731
    • Callera, G.E.1    Yogi, A.2    Briones, A.M.3    Montezano, A.C.4    He, Y.5    Tostes, R.C.6    Schiffrin, E.L.7    Touyz, R.M.8
  • 8
    • 84880695716 scopus 로고    scopus 로고
    • Mineralocorticoid receptors and the heart, multiple cell types and multiple mechanisms: A focus on the cardiomyocyte
    • 23829554
    • Mineralocorticoid receptors and the heart, multiple cell types and multiple mechanisms: a focus on the cardiomyocyte. Bienvenu LA, Reichelt ME, Delbridge LM, Young MJ, Clin Sci (Lond) 2013 125 9 409 421 10.1042/CS20130050 23829554
    • (2013) Clin Sci (Lond) , vol.125 , Issue.9 , pp. 409-421
    • Bienvenu, L.A.1    Reichelt, M.E.2    Delbridge, L.M.3    Young, M.J.4
  • 10
    • 84894939299 scopus 로고    scopus 로고
    • Aldosterone promotes vascular remodeling by direct effects on smooth muscle cell mineralocorticoid receptors
    • 24311380
    • Aldosterone promotes vascular remodeling by direct effects on smooth muscle cell mineralocorticoid receptors. Pruthi D, McCurley A, Aronovitz M, Galayda C, Karumanchi SA, Jaffe IZ, Arterioscler Thromb Vasc Biol 2014 34 2 355 364 10.1161/ATVBAHA.113.302854 24311380
    • (2014) Arterioscler Thromb Vasc Biol , vol.34 , Issue.2 , pp. 355-364
    • Pruthi, D.1    McCurley, A.2    Aronovitz, M.3    Galayda, C.4    Karumanchi, S.A.5    Jaffe, I.Z.6
  • 14
    • 84878246840 scopus 로고    scopus 로고
    • Aldosterone-induced osteopontin expression in vascular smooth muscle cells involves MR, ERK, and p38 MAPK
    • 22588951
    • Aldosterone-induced osteopontin expression in vascular smooth muscle cells involves MR, ERK, and p38 MAPK. Fu GX, Xu CC, Zhong Y, Zhu DL, Gao PJ, Endocrine 2012 42 3 676 683 10.1007/s12020-012-9675-2 22588951
    • (2012) Endocrine , vol.42 , Issue.3 , pp. 676-683
    • Fu, G.X.1    Xu, C.C.2    Zhong, Y.3    Zhu, D.L.4    Gao, P.J.5
  • 16
    • 15744377168 scopus 로고    scopus 로고
    • Aldosterone activates vascular p38MAP kinase and NADPH oxidase via c-Src
    • 15699470
    • Aldosterone activates vascular p38MAP kinase and NADPH oxidase via c-Src. Callera GE, Touyz RM, Tostes RC, Yogi A, He Y, Malkinson S, Schiffrin EL, Hypertension 2005 45 4 773 779 10.1161/01.HYP.0000154365.30593.d3 15699470
    • (2005) Hypertension , vol.45 , Issue.4 , pp. 773-779
    • Callera, G.E.1    Touyz, R.M.2    Tostes, R.C.3    Yogi, A.4    He, Y.5    Malkinson, S.6    Schiffrin, E.L.7
  • 17
    • 0344149979 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase and proliferation of human vascular smooth muscle cells
    • 8769745
    • Mitogen-activated protein kinase and proliferation of human vascular smooth muscle cells. Mii S, Khalil RA, Morgan KG, Ware JA, Kent KC, Am J Physiol 1996 270 142 H150 8769745
    • (1996) Am J Physiol , vol.270 , pp. 8142-H150
    • Mii, S.1    Khalil, R.A.2    Morgan, K.G.3    Ware, J.A.4    Kent, K.C.5
  • 19
    • 79955974994 scopus 로고    scopus 로고
    • The role of aldosterone in the metabolic syndrome
    • The role of aldosterone in the metabolic syndrome. Briet M, Schiffrin EL, Curr Hypertens Rep 2011 3 163 172
    • (2011) Curr Hypertens Rep , vol.3 , pp. 163-172
    • Briet, M.1    Schiffrin, E.L.2
  • 20
    • 17144421237 scopus 로고    scopus 로고
    • Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism
    • 15837256
    • Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism. Milliez P, Girerd X, Plouin PF, Blacher J, Safar ME, Mourad JJ, J Am Coll Cardiol 2005 45 1243 1248 10.1016/j.jacc.2005.01.015 15837256
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1243-1248
    • Milliez, P.1    Girerd, X.2    Plouin, P.F.3    Blacher, J.4    Safar, M.E.5    Mourad, J.J.6
  • 26
    • 0030048496 scopus 로고    scopus 로고
    • Oxidative stress and diabetic vascular complications
    • 8742574
    • Oxidative stress and diabetic vascular complications. Giugliano D, Ceriello A, Paolisso G, Diabetes Care 1996 19 3 257 267 10.2337/diacare.19.3.257 8742574
    • (1996) Diabetes Care , vol.19 , Issue.3 , pp. 257-267
    • Giugliano, D.1    Ceriello, A.2    Paolisso, G.3
  • 27
    • 0030871260 scopus 로고    scopus 로고
    • Vascular dysfunction in diabetes mellitus
    • 9250277
    • Vascular dysfunction in diabetes mellitus. Feener EP, King GL, Lancet 1997 350 1 I9 SI13 9250277
    • (1997) Lancet , vol.350 , Issue.1 , pp. 19I9-SI13
    • Feener, E.P.1    King, G.L.2
  • 28
    • 0141615827 scopus 로고    scopus 로고
    • Diabetes and vascular disease: Pathophysiology, clinical consequences, and medical therapy: Part i
    • Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I. Creager MA, Lüscher TF, Cosentino F, Beckman JA, Circulation 2003 23 suppl. 12 1527 1532
    • (2003) Circulation , vol.23 , pp. 1527-1532
    • Creager, M.A.1    Lüscher, T.F.2    Cosentino, F.3    Beckman, J.A.4
  • 29
    • 34547485312 scopus 로고    scopus 로고
    • The endothelium and vascular inflammation in diabetes
    • 17654441
    • The endothelium and vascular inflammation in diabetes. Hartge MM, Unger T, Kintscher U, Diab Vasc Dis Res 2007 4 2 84 88 17654441
    • (2007) Diab Vasc Dis Res , vol.4 , Issue.2 , pp. 84-88
    • Hartge, M.M.1    Unger, T.2    Kintscher, U.3
  • 30
    • 34548850880 scopus 로고    scopus 로고
    • Aldosterone suppresses insulin signaling via the downregulation of insulin receptor substrate-1 in vascular smooth muscle cells
    • 17646573
    • Aldosterone suppresses insulin signaling via the downregulation of insulin receptor substrate-1 in vascular smooth muscle cells. Hitomi H, Kiyomoto H, Nishiyama A, Hara T, Moriwaki K, Kaifu K, Ihara G, Fujita Y, Ugawa T, Kohno M, Hypertension 2007 50 750 755 10.1161/HYPERTENSIONAHA.107.093955 17646573
    • (2007) Hypertension , vol.50 , pp. 750-755
    • Hitomi, H.1    Kiyomoto, H.2    Nishiyama, A.3    Hara, T.4    Moriwaki, K.5    Kaifu, K.6    Ihara, G.7    Fujita, Y.8    Ugawa, T.9    Kohno, M.10
  • 31
    • 0032439937 scopus 로고    scopus 로고
    • Angiotensin II stimulates both aldosterone secretion and DNA synthesis via type 1 but not type 2 receptors in bovine adrenocortical cells
    • 9854682
    • Angiotensin II stimulates both aldosterone secretion and DNA synthesis via type 1 but not type 2 receptors in bovine adrenocortical cells. Tanabe A, Naruse M, Arai K, Naruse K, Yoshimoto T, Seki T, Imaki T, Kobayashi M, Miyazaki H, Demura H, J Endocrinol Invest 1998 21 10 668 672 10.1007/BF03350796 9854682
    • (1998) J Endocrinol Invest , vol.21 , Issue.10 , pp. 668-672
    • Tanabe, A.1    Naruse, M.2    Arai, K.3    Naruse, K.4    Yoshimoto, T.5    Seki, T.6    Imaki, T.7    Kobayashi, M.8    Miyazaki, H.9    Demura, H.10
  • 32
    • 77952668483 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor-dependent oxidative stress mediates endothelial dysfunction in type 2 diabetic mice
    • Angiotensin II type 1 receptor-dependent oxidative stress mediates endothelial dysfunction in type 2 diabetic mice. Wong WT, Tian XY, Xu A, Ng CF, Lee HK, Chen ZY, Au CL, Yao X, Huang Y, Antioxid Redox Signal 2010 15 suppl. 6 757 768
    • (2010) Antioxid Redox Signal , vol.15 , pp. 757-768
    • Wong, W.T.1    Tian, X.Y.2    Xu, A.3    Ng, C.F.4    Lee, H.K.5    Chen, Z.Y.6    Au, C.L.7    Yao, X.8    Huang, Y.9
  • 33
    • 84894106381 scopus 로고    scopus 로고
    • Mineralocorticoid receptor blockade in addition to angiotensin converting enzyme inhibitor or angiotensin II receptor blocker treatment: An emerging paradigm in diabetic nephropathy: A systematic review
    • 24315413
    • Mineralocorticoid receptor blockade in addition to angiotensin converting enzyme inhibitor or angiotensin II receptor blocker treatment: an emerging paradigm in diabetic nephropathy: a systematic review. Mavrakanas TA, Gariani K, Martin PY, Eur J Intern Med 2014 25 2 173 176 10.1016/j.ejim.2013.11.007 24315413
    • (2014) Eur J Intern Med , vol.25 , Issue.2 , pp. 173-176
    • Mavrakanas, T.A.1    Gariani, K.2    Martin, P.Y.3
  • 34
    • 0034700790 scopus 로고    scopus 로고
    • Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: Results of the HOPE study and MICRO-HOPE substudy
    • 10675071
    • Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators, Lancet 2000 355 253 259 10675071
    • (2000) Lancet , vol.355 , pp. 253-259
    • Heart Outcomes Prevention Evaluation Study Investigators1
  • 35
    • 84886023778 scopus 로고    scopus 로고
    • Safety and efficacy of eplerenone in patients at high risk for hyperkalemia and/or worsening renal function: Analyses of the EMPHASIS-HF study subgroups (Eplerenone in Mild Patients Hospitalization and SurvIval Study in Heart Failure)
    • Safety and efficacy of eplerenone in patients at high risk for hyperkalemia and/or worsening renal function: analyses of the EMPHASIS-HF study subgroups (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure). Eschalier R1, McMurray JJ, Swedberg K, van Veldhuisen DJ, Krum H, Pocock SJ, Shi H, Vincent J, Rossignol P, Zannad F, Pitt B, J Am Coll Cardiol 2013 22 suppl. 17 1585 1593
    • (2013) J Am Coll Cardiol , vol.22 , pp. 1585-1593
    • Eschalier, R.1    McMurray, J.J.2    Swedberg, K.3    Van Veldhuisen, D.J.4    Krum, H.5    Pocock, S.J.6    Shi, H.7    Vincent, J.8    Rossignol, P.9    Zannad, F.10    Pitt, B.11
  • 38
    • 19044393872 scopus 로고    scopus 로고
    • Adipose tissue, inflammation, and cardiovascular disease
    • 15890981
    • Adipose tissue, inflammation, and cardiovascular disease. Berg AH, Scherer PE, Circ Res 2005 96 939 949 10.1161/01.RES.0000163635.62927.34 15890981
    • (2005) Circ Res , vol.96 , pp. 939-949
    • Berg, A.H.1    Scherer, P.E.2
  • 39
    • 84856325649 scopus 로고    scopus 로고
    • Mineralocorticoid receptors in vascular function and disease
    • 21723914
    • Mineralocorticoid receptors in vascular function and disease. McCurley A, Jaffe IZ, Mol Cell Endocrinol 2012 350 256 265 10.1016/j.mce.2011.06.014 21723914
    • (2012) Mol Cell Endocrinol , vol.350 , pp. 256-265
    • McCurley, A.1    Jaffe, I.Z.2
  • 40
    • 84873027749 scopus 로고    scopus 로고
    • Mineralocorticoid receptor-mediated vascular insulin resistance: An early contributor to diabetes-related vascular disease?
    • 23349535
    • Mineralocorticoid receptor-mediated vascular insulin resistance: an early contributor to diabetes-related vascular disease? Bender SB, McGraw AP, Jaffe IZ, Sowers JR, Diabetes 2013 62 suppl2 313 319 23349535
    • (2013) Diabetes , vol.62 , pp. 313-319
    • Bender, S.B.1    McGraw, A.P.2    Jaffe, I.Z.3    Sowers, J.R.4
  • 42
    • 34548419736 scopus 로고    scopus 로고
    • Insulin resistance and hyperinsulinemia are related to plasma aldosterone levels in hypertensive patients
    • 17575088
    • Insulin resistance and hyperinsulinemia are related to plasma aldosterone levels in hypertensive patients. Colussi G, Catena C, Lapenna R, Nadalini E, Chiuch A, Sechi LA, Diabetes Care 2007 30 2349 2354 10.2337/dc07-0525 17575088
    • (2007) Diabetes Care , vol.30 , pp. 2349-2354
    • Colussi, G.1    Catena, C.2    Lapenna, R.3    Nadalini, E.4    Chiuch, A.5    Sechi, L.A.6
  • 44
    • 70449718904 scopus 로고    scopus 로고
    • Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice
    • 19505930
    • Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice. Hirata A, Maeda N, Hiuge A, Hibuse T, Fujita K, Okada T, Kihara S, Funahashi T, Shimomura I, Cardiovasc Res 2009 84 164 172 10.1093/cvr/cvp191 19505930
    • (2009) Cardiovasc Res , vol.84 , pp. 164-172
    • Hirata, A.1    Maeda, N.2    Hiuge, A.3    Hibuse, T.4    Fujita, K.5    Okada, T.6    Kihara, S.7    Funahashi, T.8    Shimomura, I.9
  • 45
    • 63849107748 scopus 로고    scopus 로고
    • Aldosterone inhibits insulin-induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3 T3-L1 adipocytes
    • 19095745
    • Aldosterone inhibits insulin-induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3 T3-L1 adipocytes. Wada T, Ohshima S, Fujisawa E, Koya D, Tsuneki H, Sasaoka T, Endocrinology 2009 150 1662 1669 10.1210/en.2008-1018 19095745
    • (2009) Endocrinology , vol.150 , pp. 1662-1669
    • Wada, T.1    Ohshima, S.2    Fujisawa, E.3    Koya, D.4    Tsuneki, H.5    Sasaoka, T.6
  • 47
    • 77049132676 scopus 로고
    • The amino-acid sequence in the glycyl chain of insulin: I: The identification of lower peptides from partial hydrolysates
    • 13032078
    • The amino-acid sequence in the glycyl chain of insulin: I: the identification of lower peptides from partial hydrolysates. Sanger F, Thompson EO, Biochem J 1953 53 suppl3 353 366 13032078
    • (1953) Biochem J , vol.53 , pp. 353-366
    • Sanger, F.1    Thompson, E.O.2
  • 48
    • 0032798782 scopus 로고    scopus 로고
    • Plasma aldosterone, plasma lipoproteins, obesity and insulin resistance in humans
    • 10471129
    • Plasma aldosterone, plasma lipoproteins, obesity and insulin resistance in humans. Goodfriend TL, Egan BM, Kelley DE, Prostaglandins Leukot Essent Fatty Acids 1999 60 suppl5-6 401 405 10471129
    • (1999) Prostaglandins Leukot Essent Fatty Acids , vol.60 , Issue.6 , pp. 401-405
    • Goodfriend, T.L.1    Egan, B.M.2    Kelley, D.E.3
  • 49
    • 0025869252 scopus 로고
    • Fatty acids are potential endogenous regulators of aldosterone secretion
    • 2019263
    • Fatty acids are potential endogenous regulators of aldosterone secretion. Goodfriend TL, Ball DL, Elliott ME, Morrison AR, Evenson MA, Endocrinology 1991 128 5 2511 2519 10.1210/endo-128-5-2511 2019263
    • (1991) Endocrinology , vol.128 , Issue.5 , pp. 2511-2519
    • Goodfriend, T.L.1    Ball, D.L.2    Elliott, M.E.3    Morrison, A.R.4    Evenson, M.A.5
  • 50
    • 0036293591 scopus 로고    scopus 로고
    • Leptin signaling, adiposity, and energy balance
    • 12079865
    • Leptin signaling, adiposity, and energy balance. Jéquier E, Ann N Y Acad Sci 2002 967 379 388 12079865
    • (2002) Ann N y Acad Sci , vol.967 , pp. 379-388
    • Jéquier, E.1
  • 51
    • 0031606279 scopus 로고    scopus 로고
    • Chronic leptin infusion increases arterial pressure
    • 9453337
    • Chronic leptin infusion increases arterial pressure. Shek EW, Brands MW, Hall JE, Hypertension 1998 31 pt 2 409 414 9453337
    • (1998) Hypertension , vol.31 , pp. 409-414
    • Shek, E.W.1    Brands, M.W.2    Hall, J.E.3
  • 52
    • 0030771886 scopus 로고    scopus 로고
    • Human leptin has natriuretic activity in the rat
    • 9087676
    • Human leptin has natriuretic activity in the rat. Jackson EK, Li P, Am J Physiol 1997 272 pt 2 333 F338 9087676
    • (1997) Am J Physiol , vol.272 , pp. 6333-F338
    • Jackson, E.K.1    Li, P.2
  • 53
    • 0030919919 scopus 로고    scopus 로고
    • Evidence for a novel peripheral action of leptin as a metabolic signal to the adrenal gland: Leptin inhibits cortisol release directly
    • 9200662
    • Evidence for a novel peripheral action of leptin as a metabolic signal to the adrenal gland: leptin inhibits cortisol release directly. Bornstein SR, Uhlmann K, Haidan A, Ehrhart-Bornstein M, Scherbaum WA, Diabetes 1997 46 1235 1238 10.2337/diab.46.7.1235 9200662
    • (1997) Diabetes , vol.46 , pp. 1235-1238
    • Bornstein, S.R.1    Uhlmann, K.2    Haidan, A.3    Ehrhart-Bornstein, M.4    Scherbaum, W.A.5
  • 54
    • 0031843357 scopus 로고    scopus 로고
    • Leptin and the renin-angiotensin-aldosterone system
    • 9719071
    • Leptin and the renin-angiotensin-aldosterone system. Bornstein SR, Torpy DJ, Hypertension 1998 32 376 377 10.1161/01.HYP.32.2.376 9719071
    • (1998) Hypertension , vol.32 , pp. 376-377
    • Bornstein, S.R.1    Torpy, D.J.2
  • 55
    • 80051474126 scopus 로고    scopus 로고
    • Impact of leptin-mediated sympatho-activation on cardiovascular function in obese mice
    • 21690486
    • Impact of leptin-mediated sympatho-activation on cardiovascular function in obese mice. Belin de Chantemèle EJ, Mintz JD, Rainey WE, Stepp DW, Hypertension 2011 58 suppl2 271 279 21690486
    • (2011) Hypertension , vol.58 , pp. 271-279
    • Belin De Chantemèle, E.J.1    Mintz, J.D.2    Rainey, W.E.3    Stepp, D.W.4
  • 56
    • 77049157238 scopus 로고
    • The amino-acid sequence in the glycyl chain of insulin. II: The investigation of peptides from enzymi hydrolysates
    • 13032079
    • The amino-acid sequence in the glycyl chain of insulin. II: the investigation of peptides from enzymi hydrolysates. Sanger F, Thompson EO, Biochem J 1953 53 suppl3 366 374 13032079
    • (1953) Biochem J , vol.53 , pp. 366-374
    • Sanger, F.1    Thompson, E.O.2
  • 57
    • 10844223660 scopus 로고    scopus 로고
    • Insulin and its receptor: Structure, function and evolution
    • 15551269
    • Insulin and its receptor: structure, function and evolution. De Meyts P, Bioessays 2004 26 suppl12 1351 1362 15551269
    • (2004) Bioessays , vol.26 , pp. 1351-1362
    • De Meyts, P.1
  • 58
    • 84875966088 scopus 로고    scopus 로고
    • Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes
    • Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes. Fu Z, Gilbert ER, Liu D, Curr Diabetes Rev 2013 1 suppl1 25 53
    • (2013) Curr Diabetes Rev , vol.1 , pp. 25-53
    • Fu, Z.1    Gilbert, E.R.2    Liu, D.3
  • 60
    • 77956751025 scopus 로고
    • Insulin: The structure in the crystal and its reflection in chemistry and biology
    • Insulin: the structure in the crystal and its reflection in chemistry and biology. Blundell T, Dodson G, Hodgkin D, Mercola D, Adv Protein Chem 1972 1972 26 279 402
    • (1972) Adv Protein Chem , vol.1972 , Issue.26 , pp. 279-402
    • Blundell, T.1    Dodson, G.2    Hodgkin, D.3    Mercola, D.4
  • 62
    • 0037663840 scopus 로고    scopus 로고
    • Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin
    • Inhibiting NOS blocks microvascular recruitment and blunts muscle glucose uptake in response to insulin. Vincent MA, Barrett EJ, Lindner JR, Clark MG, Rattigan S, Am J Physiol 2003 285 123 E129
    • (2003) Am J Physiol , vol.285 , pp. 5123-E129
    • Vincent, M.A.1    Barrett, E.J.2    Lindner, J.R.3    Clark, M.G.4    Rattigan, S.5
  • 64
    • 13844296424 scopus 로고    scopus 로고
    • Insulin-stimulated endothelial nitric oxide release is calcium independent and mediated via protein kinase B
    • Insulin-stimulated endothelial nitric oxide release is calcium independent and mediated via protein kinase B. Hartell NA, Archer HE, Bailey CJ, Biochem Pharmacol 2005 1 suppl5 781 790
    • (2005) Biochem Pharmacol , vol.1 , pp. 781-790
    • Hartell, N.A.1    Archer, H.E.2    Bailey, C.J.3
  • 65
    • 33646178955 scopus 로고    scopus 로고
    • Reciprocal relationships between insulin resistance and endothelial dysfunction: Molecular and pathophysiological mechanisms
    • 16618833
    • Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. Kim JA1, Montagnani M, Koh KK, Quon MJ, Circulation 2006 113 1888 1904 10.1161/CIRCULATIONAHA.105.563213 16618833
    • (2006) Circulation , vol.113 , pp. 1888-1904
    • Kim, J.1    Montagnani, M.2    Koh, K.K.3    Quon, M.J.4
  • 66
    • 0028625382 scopus 로고
    • Nitric oxide
    • Nitric oxide. Moncada S, J Hypertens 1994 12 35 S39
    • (1994) J Hypertens , vol.12 , pp. 1935-S39
    • Moncada, S.1
  • 68
    • 33845285226 scopus 로고    scopus 로고
    • AKT phosphorylation is essential for insulin-induced relaxation of rat vascular smooth muscle cells
    • 16855220
    • AKT phosphorylation is essential for insulin-induced relaxation of rat vascular smooth muscle cells. Lee JH, Ragolia L, Am J Physiol Cell Physiol 2006 291 suppl6 1355 C1365 16855220
    • (2006) Am J Physiol Cell Physiol , vol.291 , pp. 31355-C1365
    • Lee, J.H.1    Ragolia, L.2
  • 69
    • 1942437497 scopus 로고    scopus 로고
    • Insulin resistance and hypertension
    • 15072967
    • Insulin resistance and hypertension. Sowers JR, Am J Physiol Heart Circ Physiol 2004 286 1597 H1602 10.1152/ajpheart.00026.2004 15072967
    • (2004) Am J Physiol Heart Circ Physiol , vol.286 , pp. 81597-H1602
    • Sowers, J.R.1
  • 73
    • 77649291571 scopus 로고    scopus 로고
    • Aldosterone: Role in the cardiometabolic syndrome and resistant hypertension
    • 20226958
    • Aldosterone: role in the cardiometabolic syndrome and resistant hypertension. Whaley-Connell A, Johnson MS, Sowers JR, Prog Cardiovasc Dis 2010 52 suppl5 401 409 20226958
    • (2010) Prog Cardiovasc Dis , vol.52 , pp. 401-409
    • Whaley-Connell, A.1    Johnson, M.S.2    Sowers, J.R.3
  • 74
    • 0033042504 scopus 로고    scopus 로고
    • Moderate dietary salt restriction increases vascular and systemic insulin resistance
    • 10371376
    • Moderate dietary salt restriction increases vascular and systemic insulin resistance. Feldman RD, Schmidt ND, Am J Hypertens 1999 12 643 647 10.1016/S0895-7061(99)00016-3 10371376
    • (1999) Am J Hypertens , vol.12 , pp. 643-647
    • Feldman, R.D.1    Schmidt, N.D.2
  • 75
    • 0024358352 scopus 로고
    • Insulin-like growth factor i receptor α-subunit heterogeneity: Evidence for hybrid tetramers composed of insulin-like growth factor i and insulin receptor heterodimers
    • 2546949
    • Insulin-like growth factor I receptor α-subunit heterogeneity: evidence for hybrid tetramers composed of insulin-like growth factor I and insulin receptor heterodimers. Moxham CP, Duronio V, Jacobs S, J Biol Chem 1989 264 13238 13244 2546949
    • (1989) J Biol Chem , vol.264 , pp. 13238-13244
    • Moxham, C.P.1    Duronio, V.2    Jacobs, S.3
  • 76
    • 0026038883 scopus 로고
    • Insulin and insulin-like growth factor-1 binding specificity is determined by distinct regions of their cognate receptors
    • 1655782
    • Insulin and insulin-like growth factor-1 binding specificity is determined by distinct regions of their cognate receptors. Schumacher R, Mosthaf L, Schlessinger J, Brandenburg D, Ullrich A, J Biol Chem 1991 266 19288 19295 1655782
    • (1991) J Biol Chem , vol.266 , pp. 19288-19295
    • Schumacher, R.1    Mosthaf, L.2    Schlessinger, J.3    Brandenburg, D.4    Ullrich, A.5
  • 77
    • 0027513284 scopus 로고
    • Relationship between β subunit ligand occupancy and α- Subunit autophosphorylation in insulin/insulin-like growth factor-1 hybrid receptors
    • 8463272
    • Relationship between β subunit ligand occupancy and α- subunit autophosphorylation in insulin/insulin-like growth factor-1 hybrid receptors. Frattali AL, Pessin JE, J Biol Chem 1993 268 7393 7400 8463272
    • (1993) J Biol Chem , vol.268 , pp. 7393-7400
    • Frattali, A.L.1    Pessin, J.E.2
  • 78
    • 53649106687 scopus 로고    scopus 로고
    • The role of IGF-system in vascular insulin resistance
    • 18792869
    • The role of IGF-system in vascular insulin resistance. Arnqvist HJ, Horm Metab Res 2008 40 588 592 10.1055/s-0028-1082325 18792869
    • (2008) Horm Metab Res , vol.40 , pp. 588-592
    • Arnqvist, H.J.1
  • 79
    • 0029789432 scopus 로고    scopus 로고
    • Insulin-stimulated production of nitric oxide is inhibited by wortmannin: Direct measurement in vascular endothelial cells
    • 8770859
    • Insulin-stimulated production of nitric oxide is inhibited by wortmannin: direct measurement in vascular endothelial cells. Zeng G, Quon MJ, J Clin Invest 1996 98 894 898 10.1172/JCI118871 8770859
    • (1996) J Clin Invest , vol.98 , pp. 894-898
    • Zeng, G.1    Quon, M.J.2
  • 80
    • 0034603858 scopus 로고    scopus 로고
    • Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells
    • 10747347
    • Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Zeng G, Nystrom FH, Ravichandran LV, Cong LN, Kirby M, Mostowski H, Quon MJ, Circulation 2000 101 1539 1545 10.1161/01.CIR.101.13.1539 10747347
    • (2000) Circulation , vol.101 , pp. 1539-1545
    • Zeng, G.1    Nystrom, F.H.2    Ravichandran, L.V.3    Cong, L.N.4    Kirby, M.5    Mostowski, H.6    Quon, M.J.7
  • 81
    • 0035839532 scopus 로고    scopus 로고
    • Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179)
    • 11402048
    • Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179). Montagnani M, Chen H, Barr VA, Quon MJ, J Biol Chem 2001 276 suppl32 30392 30398 11402048
    • (2001) J Biol Chem , vol.276 , pp. 30392-30398
    • Montagnani, M.1    Chen, H.2    Barr, V.A.3    Quon, M.J.4
  • 83
    • 50449108911 scopus 로고    scopus 로고
    • Beneficial effects of exogenous tetrahydrobiopterin on left ventricular remodeling after myocardial infarction in rats: The possible role of oxidative stress caused by uncoupled endothelial nitric oxide synthase
    • 18724032
    • Beneficial effects of exogenous tetrahydrobiopterin on left ventricular remodeling after myocardial infarction in rats: the possible role of oxidative stress caused by uncoupled endothelial nitric oxide synthase. Masano T, Kawashima S, Toh R, Satomi-Kobayashi S, Shinohara M, Takaya T, Sasaki N, Takeda M, Tawa H, Yamashita T, Yokoyama M, Hirata K, Circ J 2008 72 suppl9 1512 1519 18724032
    • (2008) Circ J , vol.72 , pp. 1512-1519
    • Masano, T.1    Kawashima, S.2    Toh, R.3    Satomi-Kobayashi, S.4    Shinohara, M.5    Takaya, T.6    Sasaki, N.7    Takeda, M.8    Tawa, H.9    Yamashita, T.10    Yokoyama, M.11    Hirata, K.12
  • 84
    • 61549102774 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 receptor expression masks the antiinflammatory and glucose uptake capacity of insulin in vascular smooth muscle cells
    • 19122171
    • Insulin-like growth factor-1 receptor expression masks the antiinflammatory and glucose uptake capacity of insulin in vascular smooth muscle cells. Engberding N, San Martín A, Martin-Garrido A, Koga M, Pounkova L, Lyons E, Lassègue B, Griendling KK, Arterioscler Thromb Vasc Biol 2009 29 408 415 10.1161/ATVBAHA.108.181727 19122171
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 408-415
    • Engberding, N.1    San Martín, A.2    Martin-Garrido, A.3    Koga, M.4    Pounkova, L.5    Lyons, E.6    Lassègue, B.7    Griendling, K.K.8
  • 85
    • 78649888159 scopus 로고    scopus 로고
    • Aldosterone enhances IGF-I-mediated signaling and biological function in vascular smooth muscle cells
    • 20881255
    • Aldosterone enhances IGF-I-mediated signaling and biological function in vascular smooth muscle cells. Cascella T, Radhakrishnan Y, Maile LA, Busby WH Jr, Gollahon K, Colao A, Clemmons DR, Endocrinology 2010 151 suppl12 5851 5864 20881255
    • (2010) Endocrinology , vol.151 , pp. 5851-5864
    • Cascella, T.1    Radhakrishnan, Y.2    Maile, L.A.3    Busby, W.H.4    Gollahon, K.5    Colao, A.6    Clemmons, D.R.7
  • 86
    • 0033542476 scopus 로고    scopus 로고
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    • Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM, Nature 1999 10 suppl6736 601 605
    • (1999) Nature , vol.10 , pp. 601-605
    • Dimmeler, S.1    Fleming, I.2    Fisslthaler, B.3    Hermann, C.4    Busse, R.5    Zeiher, A.M.6


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