The insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endothelium

Diabetes

Volumn 60, Issue 8, 2011, Pages 2169-2178

  Abbas, Afroze ^a   Imrie, Helen ^a   Viswambharan, Hema ^a   Sukumar, Piruthivi ^a   Rajwani, Adil ^a   Cubbon, Richard M ^a   Gage, Matthew ^a   Smith, Jessica ^a   Galloway, Stacey ^a   Yuldeshava, Nadira ^a   Kahn, Matthew ^a   Xuan, Shouhong ^b   Grant, Peter J ^a   Channon, Keith M ^c   Beech, David J ^a   Wheatcroft, Stephen B ^a   Kearney, Mark T ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; INSULIN; INSULIN RECEPTOR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; SOMATOMEDIN C RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GLUCOSE INTOLERANCE; HAPLOINSUFFICIENCY; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SIGNAL TRANSDUCTION; STOICHIOMETRY; VASODILATATION;

ANIMALS; AORTA; BIOLOGICAL AVAILABILITY; DOWN-REGULATION; ENDOTHELIAL CELLS; GLUCOSE; GLUCOSE INTOLERANCE; HUMANS; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PHENYLEPHRINE; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; UMBILICAL VEINS; VASOCONSTRICTION;

EID: 80052860823     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0197     Document Type: Article

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