Intracellular trafficking pathways for nuclear delivery of plasmid DNA complexed with highly efficient endosome escape polymers

Biomacromolecules

Volumn 15, Issue 10, 2014, Pages 3569-3576

  Gillard, Marianne ^a   Jia, Zhongfan ^a   Hou, Jeff Jia Cheng ^a   Song, Michael ^a   Gray, Peter P ^a   Munro, Trent P ^a,b   Monteiro, Michael J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; BLOCK COPOLYMERS; DNA; GENE EXPRESSION;

GENE EXPRESSION LEVELS; GENETIC MATERIALS; HYDROPHOBIC MONOMERS; INTRACELLULAR TRAFFICKING; NUCLEAR DELIVERY; NUCLEAR ENVELOPE; PLASMID DNA (PDNA); TRANSFECTION AGENTS;

POLYMERS;

CLATHRIN; COPOLYMER; PLASMID DNA; CATION; DNA; POLYMER;

ACTIVE TRANSPORT; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL DENSITY; CELL DIVISION; CELL NUCLEUS MEMBRANE; CELL SURFACE; CELL VIABILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; DNA CROSS LINKING; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; ENDOSOME; FLOW CYTOMETRY; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HEK293 CELL LINE; HOUSEKEEPING GENE; INTRACELLULAR TRAFFICKING; INTRACELLULAR TRANSPORT; NUCLEAR PORE; PINOCYTOSIS; PROTON NUCLEAR MAGNETIC RESONANCE; REAL TIME POLYMERASE CHAIN REACTION; SYNTHESIS; CELL NUCLEUS; HUMAN; METABOLISM; PHYSIOLOGY; PLASMID; PROCEDURES; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; CATIONS; CELL NUCLEUS; DNA; ENDOCYTOSIS; ENDOSOMES; HEK293 CELLS; HUMANS; PLASMIDS; POLYMERS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84907965022     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm5008376     Document Type: Article

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