Mechanistic studies on the uptake and intracellular trafficking of novel cyclodextrin transfection complexes by intestinal epithelial cells

International Journal of Pharmaceutics

Volumn 413, Issue 1-2, 2011, Pages 174-183

  O'Neill, Martin J ^a   Guo, Jianfeng ^a   Byrne, Colin ^b   Darcy, Raphael ^b   O'Driscoll, Caitriona M ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Cyclodextrins; Intestinal delivery; Intracellular trafficking; Non viral gene therapy; Uptake pathways

Indexed keywords

CYCLODEXTRIN; HEPARAN SULFATE; PLASMID DNA; PROTEOGLYCAN;

ARTICLE; CELL MIGRATION; CELL STRAIN CACO 2; CELL SURFACE; COMPLEX FORMATION; CONTROLLED STUDY; DNA DRUG COMPLEX; DNA TRANSFECTION; ENDOCYTOSIS; GENE EXPRESSION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; PINOCYTOSIS; PRIORITY JOURNAL;

BETA-CYCLODEXTRINS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CATIONS; CAVEOLAE; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CLATHRIN; DNA; ENDOCYTOSIS; EPITHELIAL CELLS; EXCIPIENTS; FORMAZANS; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; INTESTINES; NANOPARTICLES; PARTICLE SIZE; SULFIDES; TETRAZOLIUM SALTS; TRANSFECTION;

EID: 79957981606     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.04.021     Document Type: Article

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