Polymer nanocarrier system for endosome escape and timed release of siRNA with complete gene silencing and cell death in cancer cells

Biomacromolecules

Volumn 14, Issue 10, 2013, Pages 3386-3389

  Gu, Wenyi ^a,b   Jia, Zhongfan ^a   Truong, Nghia P ^a   Prasadam, Indira ^b   Xiao, Yin ^b   Monteiro, Michael J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL DEATH; LIVING POLYMERIZATION; MOLECULAR WEIGHT DISTRIBUTION; VIRUSES;

DELIVERY DEVICE; GENE KNOCK DOWN; LIVING RADICAL POLYMERIZATION; NARROW MOLECULAR WEIGHT DISTRIBUTIONS; POLO-LIKE KINASE 1; POLYMER CONCENTRATIONS; ROOM TEMPERATURE; SINGLE ELECTRON TRANSFER;

POLYMERS;

MONOMER; NITROGEN; PHOSPHORUS; POLO LIKE KINASE 1; POLYMER; SMALL INTERFERING RNA; DRUG CARRIER; NANOPARTICLE;

ARTICLE; ATOM TRANSFER RADICAL POLYMERIZATION; CELL DEATH; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ELECTRON TRANSPORT; ENDOSOME; ENZYMATIC DEGRADATION; ESCAPE BEHAVIOR; GENE SILENCING; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; MULTIPLE DRUG DOSE; OSTEOSARCOMA CELL; PH; PRIORITY JOURNAL; ROOM TEMPERATURE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; GENETICS; METABOLISM; OSTEOSARCOMA; PATHOLOGY; STRUCTURE ACTIVITY RELATION; TIME; TUMOR CELL LINE;

ORTHOMYXOVIRIDAE;

CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG SCREENING ASSAYS, ANTITUMOR; ENDOSOMES; GENE SILENCING; HUMANS; HYDROGEN-ION CONCENTRATION; MOLECULAR STRUCTURE; NANOPARTICLES; OSTEOSARCOMA; POLYMERS; RNA, SMALL INTERFERING; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 84885658911     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm401139e     Document Type: Article

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