Blockade of indoleamine 2,3-dioxygenase reduces mortality from peritonitis and sepsis in mice by regulating functions of CD11b+ peritoneal cells

Infection and Immunity

Volumn 82, Issue 11, 2014, Pages 4487-4495

  Hoshi, Masato ^a,c   Osawa, Yosuke ^b   Ito, Hiroyasu ^c   Ohtaki, Hirofumi ^c   Ando, Tatsuya ^c   Takamatsu, Manabu ^c   Hara, Akira ^c   Saito, Kuniaki ^d   Seishima, Mitsuru ^c  

^a SUZUKA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b TOKYO METROPOLITAN KOMAGOME HOSPITAL   (Japan)

^c GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD11B ANTIGEN; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; INDOLEAMINE 2,3 DIOXYGENASE; INDOLEAMINE 2,3 DIOXYGENASE 1; INDOXIMOD; KYNURENINE; MESSENGER RNA; UNCLASSIFIED DRUG; IDO1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL COUNT; BACTERIAL PERITONITIS; BONE MARROW CELL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOREGULATION; LEUKOCYTE MIGRATION; MALE; MONONUCLEAR CELL; MORTALITY; MOUSE; NEUTROPHIL; NONHUMAN; PERITONEAL CAVITY; PERITONEUM CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEPSIS; ANIMAL; ANTAGONISTS AND INHIBITORS; BACTERIAL INFECTION; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; PERITONEUM; PERITONITIS;

ANIMALS; ANTIGENS, CD11B; BACTERIAL INFECTIONS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; LEUKOCYTES, MONONUCLEAR; MALE; MICE; MICE, KNOCKOUT; NEUTROPHILS; PERITONEUM; PERITONITIS; RNA, MESSENGER; SEPSIS;

EID: 84907961905     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.02113-14     Document Type: Article

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