An observational cohort study of the kynurenine to tryptophan ratio in sepsis: Association with impaired immune and microvascular function

PLoS ONE

Volumn 6, Issue 6, 2011, Pages

  Darcy, Christabelle J ^a   Davis, Joshua S ^a,b   Woodberry, Tonia ^a   McNeil, Yvette R ^a   Stephens, Dianne P ^b   Yeo, Tsin W ^a,b   Anstey, Nicholas M ^a,b  

^a MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

^b ROYAL DARWIN HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; KYNURENINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TRYPTOPHAN; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

ADULT; AMINO ACID BLOOD LEVEL; APOPTOSIS; ARTICLE; BLOOD VESSEL REACTIVITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; LYMPHOCYTE COUNT; LYMPHOCYTE SUBPOPULATION; LYMPHOCYTOPENIA; MAJOR CLINICAL STUDY; MALE; MICROANGIOPATHY; OBSERVATIONAL STUDY; PATHOPHYSIOLOGY; PERIPHERAL ARTERIAL TONOMETRY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SCORING SYSTEM; SEPSIS; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; SYSTOLIC BLOOD PRESSURE; T LYMPHOCYTE; TONOMETRY; TRYPTOPHAN CATABOLISM; TRYPTOPHAN METABOLISM; VASODILATATION; BIOLOGICAL MODEL; BLOOD; ENZYMOLOGY; HOSPITALIZATION; IMMUNITY; IMMUNOLOGY; METABOLISM; MICROVASCULATURE; MIDDLE AGED; PATHOLOGY; VASCULAR ENDOTHELIUM;

COHORT STUDIES; CYTOKINES; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; IMMUNITY; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; KYNURENINE; LYMPHOCYTE COUNT; MALE; MICROVESSELS; MIDDLE AGED; MODELS, BIOLOGICAL; SEPSIS; SEVERITY OF ILLNESS INDEX; TRYPTOPHAN;

EID: 79959441930     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021185     Document Type: Article

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