-
1
-
-
77949261548
-
Kynurenine is an endothelium-derived relaxing factor produced during inflammation
-
10.1038/nm.2092, 20190767
-
Wang Y, Liu H, McKenzie G, Witting PK, Stasch JP, Hahn M, Changsirivathanathamrong D, Wu BJ, Ball HJ, Thomas SR, et al. Kynurenine is an endothelium-derived relaxing factor produced during inflammation. Nat Med 2010, 16:279-285. 10.1038/nm.2092, 20190767.
-
(2010)
Nat Med
, vol.16
, pp. 279-285
-
-
Wang, Y.1
Liu, H.2
McKenzie, G.3
Witting, P.K.4
Stasch, J.P.5
Hahn, M.6
Changsirivathanathamrong, D.7
Wu, B.J.8
Ball, H.J.9
Thomas, S.R.10
-
2
-
-
64849108173
-
Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock
-
10.4049/jimmunol.0803104, 19234212
-
Jung ID, Lee MG, Chang JH, Lee JS, Jeong YI, Lee CM, Park WS, Han J, Seo SK, Lee SY, Park YM. Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock. J Immunol 2009, 182:3146-3154. 10.4049/jimmunol.0803104, 19234212.
-
(2009)
J Immunol
, vol.182
, pp. 3146-3154
-
-
Jung, I.D.1
Lee, M.G.2
Chang, J.H.3
Lee, J.S.4
Jeong, Y.I.5
Lee, C.M.6
Park, W.S.7
Han, J.8
Seo, S.K.9
Lee, S.Y.10
Park, Y.M.11
-
3
-
-
33845905763
-
The disconnect between animal models of sepsis and human sepsis
-
Rittirsch D, Hoesel LM, Ward PA. The disconnect between animal models of sepsis and human sepsis. J Leukoc Biol 2007, 81:137-143.
-
(2007)
J Leukoc Biol
, vol.81
, pp. 137-143
-
-
Rittirsch, D.1
Hoesel, L.M.2
Ward, P.A.3
-
4
-
-
0036213530
-
Inhibition of p38 mitogen-activated protein kinase: dose-dependent suppression of leukocyte and endothelial response after endotoxin challenge in humans
-
10.1097/00003246-200204000-00021, 11940756
-
Fijen JW, Tulleken JE, Kobold AC, de Boer P, Van Der Werf TS, Ligtenberg JJ, Spanjersberg R, Zijlstra JG. Inhibition of p38 mitogen-activated protein kinase: dose-dependent suppression of leukocyte and endothelial response after endotoxin challenge in humans. Crit Care Med 2002, 30:841-845. 10.1097/00003246-200204000-00021, 11940756.
-
(2002)
Crit Care Med
, vol.30
, pp. 841-845
-
-
Fijen, J.W.1
Tulleken, J.E.2
Kobold, A.C.3
de Boer, P.4
Van Der Werf, T.S.5
Ligtenberg, J.J.6
Spanjersberg, R.7
Zijlstra, J.G.8
-
5
-
-
0035000643
-
Suppression of the clinical and cytokine response to endotoxin by RWJ-67657, a p38 mitogen-activated protein-kinase inhibitor, in healthy human volunteers
-
10.1046/j.1365-2249.2001.01485.x, 1906020, 11359438
-
Fijen JW, Zijlstra JG, De Boer P, Spanjersberg R, Tervaert JW, Van Der Werf TS, Ligtenberg JJ, Tulleken JE. Suppression of the clinical and cytokine response to endotoxin by RWJ-67657, a p38 mitogen-activated protein-kinase inhibitor, in healthy human volunteers. Clin Exp Immunol 2001, 124:16-20. 10.1046/j.1365-2249.2001.01485.x, 1906020, 11359438.
-
(2001)
Clin Exp Immunol
, vol.124
, pp. 16-20
-
-
Fijen, J.W.1
Zijlstra, J.G.2
De Boer, P.3
Spanjersberg, R.4
Tervaert, J.W.5
Van Der Werf, T.S.6
Ligtenberg, J.J.7
Tulleken, J.E.8
-
6
-
-
60449106709
-
Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC-tandem mass spectrometry
-
10.1016/j.jchromb.2009.01.015, 19196554
-
de Jong WH, Smit R, Bakker SJ, de Vries EG, Kema IP. Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2009, 877:603-609. 10.1016/j.jchromb.2009.01.015, 19196554.
-
(2009)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.877
, pp. 603-609
-
-
de Jong, W.H.1
Smit, R.2
Bakker, S.J.3
de Vries, E.G.4
Kema, I.P.5
-
7
-
-
66249134941
-
Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis
-
10.1186/cc7866, 2717419, 19416526
-
Kumpers P, van Meurs M, David S, Molema G, Bijzet J, Lukasz A, Biertz F, Haller H, Zijlstra JG. Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis. Crit Care 2009, 13:R64. 10.1186/cc7866, 2717419, 19416526.
-
(2009)
Crit Care
, vol.13
-
-
Kumpers, P.1
van Meurs, M.2
David, S.3
Molema, G.4
Bijzet, J.5
Lukasz, A.6
Biertz, F.7
Haller, H.8
Zijlstra, J.G.9
-
8
-
-
81855221935
-
Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis
-
Changsirivathanathamrong D, Wang Y, Rajbhandari D, Maghzal GJ, Mak WM, Woolfe C, Duflou J, Gebski V, Dos Remedios CG, Celermajer DS, Stocker R. Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis. Crit Care Med 2011, 39:2678-2683.
-
(2011)
Crit Care Med
, vol.39
, pp. 2678-2683
-
-
Changsirivathanathamrong, D.1
Wang, Y.2
Rajbhandari, D.3
Maghzal, G.J.4
Mak, W.M.5
Woolfe, C.6
Duflou, J.7
Gebski, V.8
Dos Remedios, C.G.9
Celermajer, D.S.10
Stocker, R.11
-
9
-
-
79959441930
-
An observational cohort study of the kynurenine to tryptophan ratio in sepsis: association with impaired immune and microvascular function
-
10.1371/journal.pone.0021185, 3120841, 21731667
-
Darcy CJ, Davis JS, Woodberry T, McNeil YR, Stephens DP, Yeo TW, Anstey NM. An observational cohort study of the kynurenine to tryptophan ratio in sepsis: association with impaired immune and microvascular function. PLoS One 2011, 6:e21185. 10.1371/journal.pone.0021185, 3120841, 21731667.
-
(2011)
PLoS One
, vol.6
-
-
Darcy, C.J.1
Davis, J.S.2
Woodberry, T.3
McNeil, Y.R.4
Stephens, D.P.5
Yeo, T.W.6
Anstey, N.M.7
-
10
-
-
77949745005
-
Excessive tryptophan catabolism along the kynurenine pathway precedes ongoing sepsis in critically ill patients
-
Zeden JP, Fusch G, Holtfreter B, Schefold JC, Reinke P, Domanska G, Haas JP, Gruendling M, Westerholt A, Schuett C. Excessive tryptophan catabolism along the kynurenine pathway precedes ongoing sepsis in critically ill patients. Anaesth Intensive Care 2010, 38:307-316.
-
(2010)
Anaesth Intensive Care
, vol.38
, pp. 307-316
-
-
Zeden, J.P.1
Fusch, G.2
Holtfreter, B.3
Schefold, J.C.4
Reinke, P.5
Domanska, G.6
Haas, J.P.7
Gruendling, M.8
Westerholt, A.9
Schuett, C.10
-
11
-
-
77649084137
-
High activity of indoleamine 2,3 dioxygenase enzyme predicts disease severity and case fatality in bacteremic patients
-
10.1097/SHK.0b013e3181ad3195, 19487973
-
Huttunen R, Syrjanen J, Aittoniemi J, Oja SS, Raitala A, Laine J, Pertovaara M, Vuento R, Huhtala H, Hurme M. High activity of indoleamine 2,3 dioxygenase enzyme predicts disease severity and case fatality in bacteremic patients. Shock 2010, 33:149-154. 10.1097/SHK.0b013e3181ad3195, 19487973.
-
(2010)
Shock
, vol.33
, pp. 149-154
-
-
Huttunen, R.1
Syrjanen, J.2
Aittoniemi, J.3
Oja, S.S.4
Raitala, A.5
Laine, J.6
Pertovaara, M.7
Vuento, R.8
Huhtala, H.9
Hurme, M.10
-
12
-
-
81855185924
-
Sepsis and hypotension: enter kynurenine, move over nitric oxide
-
10.1097/CCM.0b013e31822b38a9, 22094509
-
Eiserich JP, Hayakawa KA, Cross CE. Sepsis and hypotension: enter kynurenine, move over nitric oxide. Crit Care Med 2011, 39:2767-2769. 10.1097/CCM.0b013e31822b38a9, 22094509.
-
(2011)
Crit Care Med
, vol.39
, pp. 2767-2769
-
-
Eiserich, J.P.1
Hayakawa, K.A.2
Cross, C.E.3
|