Alveolar epithelial cell chemokine expression triggered by antigen-specific cytolytic CD8+ T cell recognition

Journal of Clinical Investigation

Volumn 106, Issue 6, 2000, Pages

  Zhao, Min Q ^a   Stoler, Mark H ^a   Liu, Angela N ^a   Wei, Beiyang ^a   Soguero, Carolina ^a   Hahn, Young S ^a   Enelow, Richard I ^a,b  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CHEMOKINE; TUMOR NECROSIS FACTOR ALPHA;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL MODEL; ANTIGEN SPECIFICITY; ANTIVIRAL ACTIVITY; ARTICLE; IMMUNE RESPONSE; LUNG ALVEOLUS EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; T LYMPHOCYTE; TRANSGENE; VIRUS INFECTION;

EID: 0033800325     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI9786     Document Type: Article

References (51)

1. Braciale, T.J., Ada, G.L., and Yap, K.L. 1978. Functional and structural considerations in the recognition of virus-infected cells by cytotoxic T lymphocytes. Contemp. Top. Mol. Immunol. 7:319-371.
2. Ada, G., and Jones, P. 1986. The immune responses to influenza infection. Curr. Top. Microbiol. Immunol. 128:1-54.
3. Askonas, B. 1980. Our immune defense against influenza. Biochem. Soc. Trans. 8:257-260.
4. Leatherman, J., Michael, A., Schwartz, B., and Hoidal, J. 1984. Lung T cells in hypersensitivity pneumonitis. Ann. Intern. Med. 100:390-396.
5. Mukae, H., Kadota, J., Kohno, S., Matsukura, S., and Hara, K. 1995. Increase of activated T-cells in BAL fluid of Japanese patients with bronchiolitis obliterans organizing pneumonia and chronic eosinophilic pneumonia. Chest. 108:123-128.
6. Spurzem, J., and Rennard, S. 1996. Immunology of idiopathic pulmonary fibrosis. In Immunopathology of lung disease. R. Kradin and B. Robinson, editors. Butterworth-Heinemann, Boston, Massachusetts, USA, 119-131.
7. Karpel, J.P., and Norin, A.J. 1989. Association of activated cytolytic lung lymphocytes with response to prednisone therapy in patients with idioparhic pulmonary fibrosis. Chest. 96:794-798.
8. Costabel, U., Teschler, H., and Guzman, J. 1992. Bronchiolitis obliterans organizing pneumonia (BOOP): the cytological and immunocytological profile of bronchoalveolar lavage. Eur. Respir. J. 5:791-797.
9. Kradin, R.L., et al. 1986 Usual interstitial pneumonitis is a T-cell alveolitis. Clin. Immunol. Immunopathol. 40:224-235.
10. + T cell reactivity. J. Clin. Invest. 98:914-922.
11. + T lymphocytes. J. Clin. Invest. 102:1652-1661.
12. Liu, A.N., et al. 1999. Perforin-independent cytotoxicity in T cell-mediated cytotoxicity of alveolar epithelial cells us preferentially mediated by tumor necrosis factor-α: relative insensitivity to Fas ligand. Am. J. Respir. Cell Mol. Biol. 20:849-858.
13. Kusters, S., et al. 1997. In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis. Eur. J. Immunol. 11:2870-2875.
14. Kriegler, M., Perez, C., DeFay, K., Albert, I., and Lu, S.D. 1988. A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein ramifications for the complex physiology of TNF. Cell. 53:45-53.
15. Kinkhabwala, M., et al. 1990. A novel addition to the T cell repertory. Cell surface expression of tumor necrosis factor/cachectin by activated normal human T cells. J. Exp. Med. 171:941-946.
16. Standiford, T.J., et al. 1990. Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung. J. Clin. Invest. 86:1945-1953.
17. Sauty, A., et al. 1999. The T cell-specific CXC chemokines IP-10, Mig, and I-TAC are expressed by activated human bronchial epithelial cells. J. Immunol. 162:3549-3558.
18. Lilly, C.M., et al. 1997. Expression of cotaxin by human lung epithelial cells: induction by cytokines and inhibition by glucocorticoids. J. Clin. Invest. 99:1767-1773.
19. Lu, B., et al. 1998. Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J. Exp. Med. 187:601-608.
20. Luster, A. 1998. Chemokines: chemotactic cytokines that mediate inflammation. N. Engl. J. Med. 338:436-445.
21. Gerszten, R.E., et al. 1999. MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature. 398:718-723.
22. Graham, M., Braciale, T., and Braciale, V. 1996. Use of antiviral T-lymphocyte clones to characterize antigen presentation and T-lymphocyte subsets. Methods. 9:439-444.
23. McKall-Faienza, et al. 1998. Absence of TNlFRp55 influences virus-induced autoimmunity despite efficient lymphocytic infiltration. Int. Immunol. 10:405-412.
24. Wikenheiser, K., et al. 1993. Production of immortalized distal respiratory epithelial cell lines from surfactant protein C/simian virus 40 large tumor antigen transgenic mice. Proc. Natl. Acad. Sci. 90:11029-11033.
25. Fine, A., Anderson, N.L., Rothstein, T.L., Williams, M.C., and Gochuico, B.R. 1997. Fas expression in pulmonary alveolar type II cells. Am. J. Physiol. 273:L64-L71.
26. Kagi, D., et al. 1994. Fas and perform as major mechanisms of T cell-mediated cytotoxicity. Science. 265:528-530.
27. Kojima, H., et al. 1994. Two distinct pathways of specific killing revealed by perforin mutant cytototoxic T lymphocytes. Immunity. 1:357-364.
28. Lowin, B., Hahne, M., Mattmann, C., and Tschopp J. 1994. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lyric pathways. Nature. 370:650-652.
29. Muller, C., and Tschopp, J. 1994. Resistance of CTL to perforin-mediated lysis. Evidence for a lymphocyte membrane protein interacting with perforin. J. Immunol. 153:2470-2478.
30. Bird, C.H., et al. 1998. Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway. Mol. Cell Biol. 18:6387-6398.
31. Sun, J., et al. 1996. A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes. J. Biol. Chem. 271:27802-27809.
32. Pimentel-Muinos, F.X., and Seed, B. 1999. Regulated commitment of TNF receptor signaling; a molecular switch for death or activation. Immunity. 11:783-793.
33. Gu. L., et al. 1997. In vivo properties of monocyte chemoattractant protein-1. J. Leukoc. Biol. 62:577-580.
34. Xu, N., Chen, C.Y., and Shyu, A.B. 1997. Modulation of the fate of cytoplasmic mRNA by AU-rich elements: key sequence features controlling mRNA deadenylation and decay. Mol. Cell Biol. 17:4611-4621.
35. Black, R.A., et al. 1997, A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature. 385:729-733.
36. Kayagaki, N., et al. 1995. Metalloproteinase-mediated release of human Fas ligand. J. Exp. Med. 182:1777-1783.
37. Gearing, A.J., et al. 1994. Processing of tumour necrosis factor-alpha precursor by metalloproteinases. Nature. 370:555-557.
38. Luster, A.D., and Ravetch, J.V. 1987. Biochemical characterization of a gamma interferon-inducible cytokine (IP-10). J. Exp Med. 166:1084-1097.
39. Alwan, W.H., Kozlowska, W.J., and Openshaw, P.J. 1994. Distinct types of king disease caused by functional subsets of antiviral T cells. J. Exp. Med. 179:81-89.
40. Guidotti, L.G., and Chisan, F.V. 1996. To kill or to cure: options in host defense against viral infection. Curr Opin. Immunol. 8:478-483.
41. Kagi, D., Ledermann, B., Burki, K., Zinkernagel, R.M., and Hengartner, H. 1996. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu. Rev. Immunol. 14:207-232.
42. Openshaw, P.J. 1995. Immunopathological mechanisms in respiratory syncytial virus disease. Springer Semm. Immunopathol. 17:187-201.
43. Fiedler, M.A., Wernke-Dollries, K., and Stark, J.M. 1995. Respiratory syncytial virus increases IL-8 gene expression and protein release in A549 cells. Am. J. Physiol. 269:L865-L872.
44. Biron, C.A. 1999. Initial and innate responses to viral infections: pattern setting in immunity or disease. Curr. Opin. Microbiol. 2:374-381.
45. Selin, L.K., Varga, S.M., Wong, I.C., and Welsh, R.M. 1998. Protective heterologous antiviral immunity and enhanced immunopathogenesis medited by memory T cell populations. J. Exp. Med. 188:1705-1715.
46. + T cells in primary and secondary influenza pneumonia. Immunity. 8:683-691.
47. Chensue, S., et al. 1995. Monocyte chemotactic protein expression during schistosome egg granuloma formation. Sequence of production, localization, contribution, and regulation. Am. J. Pathol, 146:130-138.
48. Smith, R., Streiter, R., Phan, S., and Kunkel, S. 1996. C-C chemokines: novel mediators of the profibrotic response to bleomycin challenge. Am. J. Respir. Cell Mol. Biol. 15:693-702.
49. Agostini, C., et al. 1998. Involvement of the IP-10 chemokine in sarcoid granulomatous reactions. J. Immunol. 161:6413-6420.
50. Keane, M.P., et al. 1997. The CXC chemokines. IL-8 and IP-10, regulate angiogenic activity in idiopathic pulmonary fibrosis. J. Immunol. 159:1437-1443.
51. + T cell activation. J. Immunol. 160:4606-4614.