Environmental concentrations of 3,4-methylenedioxymethamphetamine (MDMA)-induced cellular stress and modulated antioxidant enzyme activity in the zebra mussel

Environmental Science and Pollution Research

Volumn 21, Issue 18, 2014, Pages 11099-11106

  Parolini, Marco ^a   Magni, Stefano ^a   Binelli, Andrea ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

3,4 Methylenedioxymethamphetamine (MDMA); Dreissena polymorpha; Sub lethal effects

Indexed keywords

ANTIOXIDANT; AQUATIC ENVIRONMENT; BIOMARKER; BIOMONITORING; BIVALVE; ENZYME ACTIVITY; SUBLETHAL EFFECT;

DREISSENA POLYMORPHA;

3,4 METHYLENEDIOXYMETHAMPHETAMINE; CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; SUPEROXIDE DISMUTASE; WATER POLLUTANT;

ANALYSIS; ANIMAL; BLOOD CELL; CELL CULTURE; CELL SURVIVAL; DNA DAMAGE; DREISSENA; DRUG EFFECTS; ENZYMOLOGY; LIPID PEROXIDATION; METABOLISM; OXIDATIVE STRESS; PROTEIN CARBONYLATION; TOXICITY; WATER POLLUTANT; WATER POLLUTION;

ANIMALS; CATALASE; CELL SURVIVAL; CELLS, CULTURED; DNA DAMAGE; DREISSENA; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HEMOCYTES; LIPID PEROXIDATION; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; OXIDATIVE STRESS; PROTEIN CARBONYLATION; SUPEROXIDE DISMUTASE; WATER POLLUTANTS, CHEMICAL; WATER POLLUTION, CHEMICAL;

EID: 84907860536     PISSN: 09441344     EISSN: 16147499     Source Type: Journal    
DOI: 10.1007/s11356-014-3094-2     Document Type: Article

References (51)

1. Alvarenga TA, Andersen ML, Ribeiro DA, Araujo P et al (2010) Single exposure to cocaine or ecstasy induces DNA damage in brain and other organs of mice. Addict Biol 15:96–99
2. Alves E, Binienda Z, Carvalho F, Alves CJ, Fernandes E, de Lourdes Bastos M, Tavares MA, Summavielle T (2009) Acetyl-L-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain. Neuroscience 158(2):514–523
3. Antolino-Lobo I, Meulenbelt J, Nijmeijer SM, Scherpenisse P, van den Berg M, van Duursen MBM (2010) Differential roles of phase I and phase II enzymes in 3,4-methylendioxymethamphetamine-induced cytotoxicity. Drug Metab Dispos 38:1105–1112
4. Barenys M, Macia N, Camp L, de Lapuente J, Gomez-Catalan J, Gonzales-Linares J, Borras M, Rodamilans M, Llobet JM (2009) Chronic exposure to MDMA (ecstasy) increases DNA damage in sperm and alters testes histopathology in male rats. Toxicol Lett 191:40–46
5. Binelli A, Cogni D, Parolini M, Riva C, Provini A (2009a) In vivo experiments for the evaluation of genotoxic and cytotoxic effects of triclosan in zebra mussel hemocytes. Aquat Toxicol 91:238–244
6. Binelli A, Parolini M, Cogni D, Pedriali A, Provini A (2009b) A multi-biomarker assessment of the impact of the antibacterial trimethoprim on the non-target organism zebra mussel (Dreissena polymorpha). Comp Biochem Physiol C 150:329–336
7. Buschini A, Carboni P, Martino A, Poli P, Rossi C (2003) Effects of temperature on baseline and genotoxicant-induced DNA damage in haemocytes of Dreissena polymorpha. Mutat Res 537:81–92
8. Carvalho M, Remião F, Milhazes N, Borges F, Fernandes E, Carvalho F, Bastos ML (2004a) The toxicity of N-methyl-alpha-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine. Toxicology 200(2–3):193–203
9. Carvalho M, Remião F, Milhazes N, Borges F, Fernandes E, Monteiro Mdo C, Gonçalves MJ, Seabra V, Amado F, Carvalho F, Bastos ML (2004b) Metabolism is required for the expression of ecstasy induced cardiotoxicity in vitro. Chem Res Toxicol 17(5):623–632
10. Castiglioni S, Zuccato E, Fanelli R (2011) Illicit drugs in the environment, 1st edn. Wiley & Sons, Inc., Hoboken
11. Cerretani D, Bello S, Cantatore S, Fiaschi AI, Montefrancesco G, Nerib M, Pomara C, Riezzo I, Fiore C, Bonsignore A, Turillazzi E, Fineschi V (2011) Acute administration of 3,4-methylenedioxymethamphetamine (MDMA) induces oxidative stress, lipoperoxidation and TNFα-mediated apoptosis in rat liver. Pharmacol Res 64:517–527
12. Coughlan J (1969) Estimation of filtering rate from clearance of suspensions. Mar Biol 2:356–358
13. Fisher AA, Labenski MT, Malladi S, Gokhale V, Bowen ME, Milleron RS, Bratton SB, Monks TJ, Lau SS (2007) Quinone electrophiles selectively adduct “electrophile binding motifs” within cytochrome c. Biochemistry 46(39):11090–11100
14. Fong PP (1998) Zebra mussel spawning is induced in low concentrations of putative serotonin reuptake inhibitors. Biol Bull 194:143–149
15. Fong PP, Philbert CM, Roberts BJ (2003) Putative serotonin reuptake inhibitor-induced spawning and parturition in freshwater bivalves is inhibited by mammalian 5-HT2 receptor antagonists. J Exp Zool 298A:67–72
16. Garcia Cabeza I, Zabala A, Soto-Montenegro ML, Arango C (2005) MDMA and serotonin: based on two cases. Actas Esp Psiquiatr 33:339–342
17. Gonzalez-Rey M, Bebianno MJ (2013) Does selective serotonin reuptake inhibitor (SSRI) fluoxetine affects mussel Mytilus galloprovincialis? Environ Pollut 173:200–209
18. Gwoździński K, Gonciarz M, Kilańczyk E, Kowalczyk A, Pieniążek A, Brichon G (2010) Antioxidant enzyme activities and lipid peroxidation in Mytilus galloprovincialis from the French Mediterranean coast. Oceanol Hydrobiol Stud 39:33–43
19. Kasprzyk-Hordern B, Kondakal VVR, Baker DR (2010) Enantiomeric analysis of drugs of abuse by chiral liquid chromatography coupled with tandem mass spectrometry. J Chromatogr A 1217:4575–4586
20. Khessiba A, Roméo MAP (2005) Effects of some environmental parameters on catalase activity measured in the mussel (Mytilus galloprovincialis) exposed to lindane. Environ Pollut 133:275–281
21. Kirsch-Volders M, Sofuni T, Aaderma M, Albertini S, Eastmond D, Fenech M, Ishidate M, Lorge E, Norppa H, Suralles J, Von der Hude W, Wakata A (2000) Report from the in vitro micronucleus assay working group. Environ Mol Mutagen 35:167–172
22. Lowe DM, Pipe RK (1994) Contaminant induced lysosomal membrane damage in marine mussel digestive cells—an in vitro study. Aquat Toxicol 30:357–365
23. Lowe DM, Fossato VU, Depledge MH (1995) Contaminant-induced lysosomal membrane damage in blood cells of mussels Mytilus galloprovincialis from the Venice Lagoon: an in vitro study. Mar Ecol Prog Ser 129:189–196
24. Mecocci P, Fano G, Fulle S, MacGarvey U, Shinobu L, Polidori MC, Cherubini A, Vecchiet J, Senin U, Beal MF (1998) Age-dependent increases in oxidative damage to DNA, lipids, and proteins in human skeletal muscle. Free Radic Biol Med 26:303–308
25. Montiel-Duarte C, Ansorena E, Lopez-Zabalza MJ, Cenarruzabeitia E, Iraburu MJ, Cenarruzabeitia E, Iraburu MJ (2004) Role of reactive oxygen species, glutathione and NF-kappaB in apoptosis induced by 3,4-methylenedioxymethamphetamine (“Ecstasy”) on hepatic stellate cells. Biochem Pharmacol 67(6):1025–1033
26. Moon KH, Upreti VV, Yu LR, Lee IJ, Ye X, Eddington ND, Veenstra TD, Song BJ (2008) Mechanism of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated mitochondrial dysfunction in rat liver. Proteomics 8(18):3906–3918
27. Mueller M, Yuan J, Felim A, Neudorffer A, Peters FT, Maurer HH, McCann UD, Largeron M, Ricaurte GA (2009) Further studies on the role of metabolites in (+/−)-3,4-methylenedioxymethamphetamine-induced serotonergic neurotoxicity. Drug Metab Dispos 37:2079–2086
28. Nakagawa Y, Suzuki T, Tayama S, Ishii H, Ogata A (2009) Cytotoxic effects of 3,4-methylenedioxy-N-alkylamphetamines, MDMA and its analogues, on isolated rat hepatocytes. Arch Toxicol 83:69–80
29. Ohkawa H, Ohisi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95:351–358
30. Orbea A, Ortiz-Zarragoitia M, Solé M, Porte C, Cajaraville MP (2002) Antioxidant enzymes and peroxisome proliferation in relation to contaminant body burdens of PAHs and PCBs in bivalve molluscs, crabs and fish from the Urdaibai and Plentzia estuaries (Bay of Biscay). Aquat Toxicol 58:75–98
31. Pal R, Megharaj M, Kirkbride KP, Naidu R (2013) Illicit drugs in environment—a review. Sci Total Environ 463–464:1079–1092
32. Palais F, Dedourge-Geffard O, Beaudon A, Pain-Devin S, Trapp J, Geffard O, Noury P, Gourlay-Francè C (2012) One-year monitoring of core biomarker and digestive enzyme responses in transplanted zebra mussels (Dreissena polymorpha). Ecotoxicology 21:888–905
33. Parolini M, Binelli A (2013) Adverse effects induced by ecgonine methyl ester to the zebra mussel: a comparison with the benzoylecgonine. Environ Pollut 182:371–378
34. Parolini M, Binelli A (2014) Oxidative and genetic responses induced by Δ-9-tetrahydrocannabinol (Δ-9-THC) to Dreissena polymorpha. Sci Total Environ 468–469:68–76
35. Parolini M, Binelli A, Cogni D, Provini A (2010) Multi-biomarker approach for the evaluation of the cyto-genotoxicity of paracetamol on zebra mussel (Dreissena polymorpha). Chemosphere 79:489–498
36. Parolini M, Binelli A, Provini A (2011a) Chronic effects induced by ibuprofen on the freshwater bivalve Dreissena polymorpha. Ecotoxicol Environ Saf 74:1586–1594
37. Parolini M, Binelli A, Provini A (2011b) Assessment of the potential cyto–genotoxicity of the nonsteroidal anti-inflammatory drug (NSAID) diclofenac on the zebra mussel (Dreissena polymorpha). Water Air Soil Pollut 217:589–601
38. Parolini M, Pedriali A, Riva C, Binelli A (2013) Sub-lethal effects caused by the cocaine metabolite benzoylecgonine to the freshwater mussel Dreissena polymorpha. Sci Total Environ 444:43–50
39. Parrott AC (2013) MDMA, serotonergic neurotoxicity, and the diverse functional deficits of recreational “Ecstasy” users. Neurosci Biobehav Rev 37:1466–1484
40. Pavlica M, Klobucar GIV, Vetma N, Erben R, Papes D (2000) Detection of micronuclei in haemocytes of zebra mussel and ramshorn snail exposed to pentachlorophenol. Mutat Res 465:145–150
41. Reid LW, Elifson KW, Sterk CE (2007) Ecstasy and gateway drugs: initiating the use of ecstasy and other drugs. Ann Epidemiol 17(1):74–80
42. Riezzo I, Fiore C, De Carlo D, Karch SB, Neri M, Turillazi TE, Fineschi V (2013) The role of oxidative stress in methamphetamine and MDMA-induced toxicity. Mini-Rev Org Chem 10:349–359
43. Santos LHMLM, Araújo AN, Fachini A, Pena A, Delerue-Matos C, Montenegro MCBSM (2010) Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment. J Hazard Mater 175:45–95
44. Singh NP (2000) A simple method for accurate estimation of apoptotic cells. Exp Cell Res 256:328–337
45. Song B-L, Moon K-H, Upreti VV, Eddington ND, Lee IJ (2010) Mechanisms of MDMA (Ecstasy)-induced oxidative stress, mitochondrial dysfunction, and organ damage. Curr Pharm Biotechnol 11(5):434–443
46. Stanley JK, Ramirez AJ, Chambliss CK, Brooks BW (2007) Enantiospecific sublethal effects of the antidepressant fluoxetine to a model aquatic vertebrate and invertebrate. Chemosphere 69:9–16
47. Styrishave B, Halling-Sørensen B, Ingerslev F (2011) Environmental risk assessment of three selective serotonin reuptake inhibitors in the aquatic environment: a case study including a cocktail scenario. Environ Toxicol Chem 30:254–261
48. van Iersel MLPS, Ploemenb J-P HTM, Struik I, van Amersfoort C, Keyzerb AE, Schefferlieb JG, van Bladeren PJ (1996) Inhibition of glutathione S-transferase activity in human melanoma cells by α, β-unsaturated carbonyl derivatives. Effects of acrolein, cinnamaldehyde, citral, crotonaldehyde, curcumin, ethacrynic acid, and trans-2-hexenal. Chem Biol Interact 102:117–132
49. van Nuijs ALN, Abdellati K, Bervoets L, Blust R, Jorens PG, Neels H, Covaci A (2012) The stability of illicit drugs and metabolites in wastewater, an important issue for sewage epidemiology? J Hazard Mater 239–240:19–23
50. Viarengo A, Lowe D, Bolognesi C, Fabbri E, Koehler A (2007) The use of biomarkers in biomonitoring: a 2-tier approach assessing the level of pollutant induced stress syndrome in sentinel organisms. Comp Biochem Physiol C 146:281–300
51. Zuccato E, Castiglioni S, Bagnati R, Chiabrando C, Grassi P, Fanelli R (2008) Illicit drugs, a novel group of environmental contaminants. Water Res 42:961–968