Acute administration of 3,4-methylenedioxymethamphetamine (MDMA) induces oxidative stress, lipoperoxidation and TNFα-mediated apoptosis in rat liver

Pharmacological Research

Volumn 64, Issue 5, 2011, Pages 517-527

  Cerretani, D ^a   Bello, S ^b   Cantatore, S ^b   Fiaschi, A I ^a   Montefrancesco, G ^a   Neri, M ^b   Pomara, C ^b   Riezzo, I ^b   Fiore, C ^b   Bonsignore, A ^b   Turillazzi, E ^b   Fineschi, V ^b  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF FOGGIA   (Italy)

Author keywords

Apoptosis; Liver; MDMA; Oxidative stress; ROS; TNF

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; ASCORBIC ACID; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MALONALDEHYDE; PROTEIN BCL 2; PROTEIN BID; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DENSITOMETRY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; IMMUNOHISTOCHEMISTRY; LIPID PEROXIDATION; LIVER CELL; LIVER CYTOSOL; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; TOXICITY TESTING; UPREGULATION; WESTERN BLOTTING;

EID: 80055022669     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2011.08.002     Document Type: Article

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