The stability of illicit drugs and metabolites in wastewater, an important issue for sewage epidemiology?

Journal of Hazardous Materials

Volumn 239-240, Issue , 2012, Pages 19-23

  van Nuijs, Alexander L N ^a   Abdellati, Karim ^a   Bervoets, Lieven ^a   Blust, Ronny ^a   Jorens, Philippe G ^a   Neels, Hugo ^a,b   Covaci, Adrian ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b ZNA Stuivenberg   (Belgium)

Author keywords

Illicit drugs; Influent wastewater; Metabolites; Sewage epidemiology; Stability

Indexed keywords

6-MONOACETYLMORPHINE; BENZOYLECGONINE; COMMUNITY OR; ILLICIT DRUG; METHYL ESTERS; STABILITY ISSUES; TRANSFORMATION PATHWAYS;

BIOMOLECULES; CONVERGENCE OF NUMERICAL METHODS; DISEASES; DRUG PRODUCTS; EPIDEMIOLOGY; SEWAGE; STABILITY;

METABOLITES;

3,4 METHYLENEDIOXYMETHAMPHETAMINE; AMPHETAMINE; BENZOYLECGONINE; COCAINE; DRUG METABOLITE; ECGONINE METHYLESTER; ILLICIT DRUG; METHADONE; METHAMPHETAMINE; MORPHINE 6 ACETATE; UNCLASSIFIED DRUG;

CONCENTRATION (COMPOSITION); DEGRADATION; DRUG; EPIDEMIOLOGY; FUTURE PROSPECT; METABOLITE; SEWAGE; SEWER NETWORK; TRANSFORMATION;

ARTICLE; COMMUNITY; DEGRADATION; POPULATION; SEWAGE; WASTE WATER MANAGEMENT;

ENVIRONMENTAL MONITORING; HYDROGEN-ION CONCENTRATION; SEWAGE; STREET DRUGS; TEMPERATURE; WATER POLLUTANTS, CHEMICAL;

EID: 84867700207     PISSN: 03043894     EISSN: 18733336     Source Type: Journal    
DOI: 10.1016/j.jhazmat.2012.04.030     Document Type: Article

References (17)

1. Frost N., Griffiths P., Fanelli R. Peering into dirty waters: the potential and implications of a new approach to monitoring drug consumption. Addiction 2008, 103:1239-1241.
2. van Nuijs A.L.N., Castiglioni S., Tarcomnicu I., Postigo C., Lopez de Alda M.J., Neels H., Zuccato E., Barcelo D., Covaci A. Illicit drug consumption estimations derived from wastewater analysis: a critical review. Sci. Total Environ. 2011, 409:3564-3577.
3. Daughton C.G. Pharmaceuticals and Personal care Products in the Environment, Scientific and Regulatory Issues 2001, 348-364. American Chemical Society, Washington. C.G. Daughton, T.L. Jones-Lepp (Eds.).
4. Zuccato E., Chiabrando C., Castiglioni S., Bagnati R., Fanelli R. Estimating community drug abuse by wastewater analysis. Environ. Health Perspect. 2008, 116:1027-1032.
5. Lai F.Y., Ort C., Gartner C., Carter S., Prichard J., Kirkbride P., Bruno R., Hall W., Eaglesham G., Mueller J.F. Refining the estimation of illicit drug consumptions from wastewater analysis: co-analysis of prescription pharmaceuticals and uncertainty assessment. Water Res. 2011, 45:4437-4448.
6. van Nuijs A.L.N., Mougel J., Tarcomnicu I., Bervoets L., Blust R., Jorens P.G., Neels H., Covaci A. Sewage epidemiology-a real-time approach to estimate the consumption of illicit drugs in Brussels, Belgium. Environ. Int. 2011, 37:612-621.
7. Castiglioni S., Zuccato E., Crisci E., Chiabrando C., Fanelli R., Bagnati R. Identification and measurement of illicit drugs and their metabolites in urban wastewater by liquid chromatography-tandem mass spectrometry. Anal. Chem. 2006, 78:8421-8429.
8. Chiaia A.C., Banta-Green C., Field J. Eliminating solid phase extraction with large-volume injection LC/MS/MS: analysis of illicit and legal drugs and human urine indicators in US wastewaters. Environ. Sci. Technol. 2008, 42:8841-8848.
9. Gheorghe A., van Nuijs A., Pecceu B., Bervoets L., Jorens P.G., Blust R., Neels H., Covaci A. Analysis of cocaine and its principal metabolites in waste and surface water using solid-phase extraction and liquid chromatography-ion trap tandem mass spectrometry. Anal. Bioanal. Chem. 2008, 391:1309-1319.
10. Gonzalez-Marino I., Quintana J.B., Rodriguez I., Cela R. Determination of drugs of abuse in water by solid-phase extraction, derivatisation and gas chromatography-ion trap-tandem mass spectrometry. J. Chromatogr. A 2010, 1217:1748-1760.
11. Baker D.R., Kasprzyk-Hordern B. Critical evaluation of methodology commonly used in sample collection, storage and preparation for the analysis of pharmaceuticals and illicit drugs in surface water and wastewater by solid phase extraction and liquid chromatography-mass spectrometry. J. Chromatogr. A 2011, 1218:8036-8059.
12. Castiglioni S., Bagnati R., Melis M., Panawennage D., Chiarelli P., Fanelli R., Zuccato E. Identification of cocaine and its metabolites in urban wastewater and comparison with the human excretion profile in urine. Water Res. 2011, 45:5141-5150.
13. K.J. Bisceglia, Ph.D. dissertation, John Hopkins University, Baltimore, 2010.
14. van Nuijs A.L.N., Tarcomnicu I., Jorens P.G., Bervoets L., Blust R., Neels H., Covaci A. Analysis of drugs of abuse in wastewater by hydrophilic interaction liquid chromatography-tandem mass spectrometry. Anal. Bioanal. Chem. 2009, 395:819-828.
15. Jimenez C., de la Torre R., Ventura M., Segura J., Ventura R. Stability studies of amphetamine and ephedrine derivatives in urine. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2006, 843:84-93.
16. Kasprzyk-Hordern B., Dinsdale R.M., Guwy A.J. Illicit drugs and pharmaceuticals in the environment-forensic applications of environmental data. Part 1: estimation of the usage of drugs in local communities. Environ. Pollut. 2009, 157:1773-1777.
17. Johansen S.S., Bhatia H.M. Quantitative analysis of cocaine and its metabolites in whole blood and urine by high-performance liquid chromatography coupled with tandem mass spectrometry. J. Chromatogr. B 2007, 852:338-344.