메뉴 건너뛰기




Volumn 150, Issue 3, 2009, Pages 329-336

A multi-biomarker assessment of the impact of the antibacterial trimethoprim on the non-target organism Zebra mussel (Dreissena polymorpha)

Author keywords

Antibiotics; Cytotoxicity; Genotoxicity; Mussels; Risk assessment

Indexed keywords

BIOLOGICAL MARKER; CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; SUPEROXIDE DISMUTASE; TRIMETHOPRIM;

EID: 67650747332     PISSN: 15320456     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpc.2009.05.011     Document Type: Article
Times cited : (57)

References (51)
  • 1
    • 33744551102 scopus 로고    scopus 로고
    • Evaluation of cytogenetic and DNA damage induced by the antibacterial drug, trimethoprim
    • Abou-Eisha A. Evaluation of cytogenetic and DNA damage induced by the antibacterial drug, trimethoprim. Toxicol. In Vitro 20 (2006) 601-607
    • (2006) Toxicol. In Vitro , vol.20 , pp. 601-607
    • Abou-Eisha, A.1
  • 2
    • 42149185532 scopus 로고    scopus 로고
    • Synthesis, characterization and antiprotozoal studies of some metal complexes of antimalarial drugs
    • Ajibade P.A., and Kolawole G.A. Synthesis, characterization and antiprotozoal studies of some metal complexes of antimalarial drugs. Transition Met. Chem. 33 (2008) 493-497
    • (2008) Transition Met. Chem. , vol.33 , pp. 493-497
    • Ajibade, P.A.1    Kolawole, G.A.2
  • 3
    • 0345382038 scopus 로고
    • Trimethoprim-sulfamethoxazole
    • Munson P.L., Mueller R., and Breese G.R. (Eds), Chapman & Hall, New York (USA)
    • Baccanari D.P. Trimethoprim-sulfamethoxazole. In: Munson P.L., Mueller R., and Breese G.R. (Eds). Principles of Pharmacology (1995), Chapman & Hall, New York (USA) 1301-1317
    • (1995) Principles of Pharmacology , pp. 1301-1317
    • Baccanari, D.P.1
  • 4
    • 45849107965 scopus 로고    scopus 로고
    • Genotoxic effects of p,p′-DDT (1,1,1-trichloro-2,2-bis-(chlorophenyl)ethane) and its metabolites in Zebra mussel (D. polymorpha) by SCGE assay and micronucleus test
    • Binelli A., Riva C., Cogni D., and Provini A. Genotoxic effects of p,p′-DDT (1,1,1-trichloro-2,2-bis-(chlorophenyl)ethane) and its metabolites in Zebra mussel (D. polymorpha) by SCGE assay and micronucleus test. Environ. Mol. Mutagen. 49 (2008) 406-415
    • (2008) Environ. Mol. Mutagen. , vol.49 , pp. 406-415
    • Binelli, A.1    Riva, C.2    Cogni, D.3    Provini, A.4
  • 5
    • 58649089584 scopus 로고    scopus 로고
    • In vivo experiments for the evaluation of genotoxic and cytotoxic effects of Triclosan in Zebra mussel hemocytes
    • Binelli A., Cogni D., Parolini M., Riva C., and Provini A. In vivo experiments for the evaluation of genotoxic and cytotoxic effects of Triclosan in Zebra mussel hemocytes. Aquat. Toxicol. 91 (2009) 238-244
    • (2009) Aquat. Toxicol. , vol.91 , pp. 238-244
    • Binelli, A.1    Cogni, D.2    Parolini, M.3    Riva, C.4    Provini, A.5
  • 6
    • 67349143218 scopus 로고    scopus 로고
    • Cytotoxic and genotoxic effects of in vitro exposures to triclosan and trimethoprim on zebra mussel (D. polymorpha) hemocytes
    • Binelli A., Cogni D., Parolini M., Riva C., and Provini A. Cytotoxic and genotoxic effects of in vitro exposures to triclosan and trimethoprim on zebra mussel (D. polymorpha) hemocytes. Comp. Biochem. Physiol. C 150 (2009) 50-56
    • (2009) Comp. Biochem. Physiol. C , vol.150 , pp. 50-56
    • Binelli, A.1    Cogni, D.2    Parolini, M.3    Riva, C.4    Provini, A.5
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein using the principle of protein-dye binding
    • Bradford M.M. A rapid and sensitive method for the quantification of microgram quantities of protein using the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 0038396291 scopus 로고    scopus 로고
    • Effects of temperature on baseline and genotoxicant-induced DNA damage in haemocytes of Dreissena polymorpha
    • Buschini A., Carboni P., Martino A., Poli P., and Rossi C. Effects of temperature on baseline and genotoxicant-induced DNA damage in haemocytes of Dreissena polymorpha. Mutat. Res. 537 (2003) 81-92
    • (2003) Mutat. Res. , vol.537 , pp. 81-92
    • Buschini, A.1    Carboni, P.2    Martino, A.3    Poli, P.4    Rossi, C.5
  • 9
    • 0036753543 scopus 로고    scopus 로고
    • Total oxyradical scavenging capacity and cell membrane stability of haemocytes of the Arctic scallop, Chlamys islandicus, following benzo(a)pyrene exposure
    • Camus L., Jones M.B., Børseth J.F., Grøsvik B.E., Regoli F., and Depledge M.H. Total oxyradical scavenging capacity and cell membrane stability of haemocytes of the Arctic scallop, Chlamys islandicus, following benzo(a)pyrene exposure. Mar. Environ. Res. 54 (2002) 425-430
    • (2002) Mar. Environ. Res. , vol.54 , pp. 425-430
    • Camus, L.1    Jones, M.B.2    Børseth, J.F.3    Grøsvik, B.E.4    Regoli, F.5    Depledge, M.H.6
  • 10
    • 42049101803 scopus 로고    scopus 로고
    • Simultaneous analysis of 16 sulfonamide and trimethoprim antibiotics in environmental waters by liquid chromatography-electrospray tandem mass spectrometry
    • Chang H., Hu J., Asami M., and Kunikane S. Simultaneous analysis of 16 sulfonamide and trimethoprim antibiotics in environmental waters by liquid chromatography-electrospray tandem mass spectrometry. J. Chromatogr., A 1190 (2008) 390-393
    • (2008) J. Chromatogr., A , vol.1190 , pp. 390-393
    • Chang, H.1    Hu, J.2    Asami, M.3    Kunikane, S.4
  • 11
    • 40949101787 scopus 로고    scopus 로고
    • Occurrences and ecological risks of roxithromycin, trimethoprim, and chloramphenicol in the Han River, Korea
    • Choi K., Kim Y., Jung J., Kim M.H., Kim C.S., Kim N.H., and Park J. Occurrences and ecological risks of roxithromycin, trimethoprim, and chloramphenicol in the Han River, Korea. Environ. Toxicol. Chem. 27 (2008) 711-719
    • (2008) Environ. Toxicol. Chem. , vol.27 , pp. 711-719
    • Choi, K.1    Kim, Y.2    Jung, J.3    Kim, M.H.4    Kim, C.S.5    Kim, N.H.6    Park, J.7
  • 12
    • 14844297299 scopus 로고    scopus 로고
    • Ecosystem response to antibiotics entering the aquatic environment
    • Costanzo S.D., Murby J., and Bates J. Ecosystem response to antibiotics entering the aquatic environment. Mar. Pollut. Bull. 51 (2005) 218-223
    • (2005) Mar. Pollut. Bull. , vol.51 , pp. 218-223
    • Costanzo, S.D.1    Murby, J.2    Bates, J.3
  • 14
    • 60949106024 scopus 로고    scopus 로고
    • Multi-biomarker responses in the freshwater mussel Dreissena polymorpha exposed to polychlorobiphenyls and metals
    • Faria M., Carrasco L., Diez S., Riva M.C., Bayona J.M., and Barata C. Multi-biomarker responses in the freshwater mussel Dreissena polymorpha exposed to polychlorobiphenyls and metals. Comp. Biochem. Physiol. C 149 (2009) 281-288
    • (2009) Comp. Biochem. Physiol. C , vol.149 , pp. 281-288
    • Faria, M.1    Carrasco, L.2    Diez, S.3    Riva, M.C.4    Bayona, J.M.5    Barata, C.6
  • 15
    • 51249095222 scopus 로고    scopus 로고
    • Environmental assessment of Norwegian priority pharmaceuticals based on the EMEA guideline
    • Grung M., Kallqvist T., Sakshaug S., Skurtveit S., and Thomas K.V. Environmental assessment of Norwegian priority pharmaceuticals based on the EMEA guideline. Ecotoxicol. Environ. Saf. 71 (2008) 328-340
    • (2008) Ecotoxicol. Environ. Saf. , vol.71 , pp. 328-340
    • Grung, M.1    Kallqvist, T.2    Sakshaug, S.3    Skurtveit, S.4    Thomas, K.V.5
  • 16
    • 0037092214 scopus 로고    scopus 로고
    • Indigenous microflora and opportunistic pathogens of the freshwater zebra mussel, Dreissena polymorpha
    • Gu J.D., and Mitchell R. Indigenous microflora and opportunistic pathogens of the freshwater zebra mussel, Dreissena polymorpha. Hydrobiologia 474 (2002) 81-90
    • (2002) Hydrobiologia , vol.474 , pp. 81-90
    • Gu, J.D.1    Mitchell, R.2
  • 18
    • 0037052865 scopus 로고    scopus 로고
    • Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data
    • Heberer T. Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: a review of recent research data. Toxicol. Lett. 131 (2002) 5-17
    • (2002) Toxicol. Lett. , vol.131 , pp. 5-17
    • Heberer, T.1
  • 19
    • 7544222053 scopus 로고    scopus 로고
    • Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition
    • Hinson J.A., Reid A.B., McCullough S.S., and James L.P. Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition. Drug Metab. Rev. 36 (2004) 805-822
    • (2004) Drug Metab. Rev. , vol.36 , pp. 805-822
    • Hinson, J.A.1    Reid, A.B.2    McCullough, S.S.3    James, L.P.4
  • 20
    • 19344377723 scopus 로고    scopus 로고
    • Moore M.N., and Lowe D. (Eds) Copenhagen, Denmark
    • ICES. In: Moore M.N., and Lowe D. (Eds). Biological Effects of Contaminants: Measurement of Lysosomal Membrane Stability. ICES Techniques in Marine Environmental Sciences vol. 36 (2004) 39 Copenhagen, Denmark
    • (2004) ICES Techniques in Marine Environmental Sciences , vol.36 , pp. 39
    • ICES1
  • 21
    • 53649084556 scopus 로고    scopus 로고
    • The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK
    • Kasprzyk-Hordern B., Dinsdaleb R.M., and Guwy A.J. The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK. Water Res. 42 (2008) 3498-3518
    • (2008) Water Res. , vol.42 , pp. 3498-3518
    • Kasprzyk-Hordern, B.1    Dinsdaleb, R.M.2    Guwy, A.J.3
  • 22
    • 33847279987 scopus 로고    scopus 로고
    • Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea
    • Kim Y., Choi K., Jung J., Park S., Kim P.G., and Park J. Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea. Environ. Int. 33 (2007) 370-375
    • (2007) Environ. Int. , vol.33 , pp. 370-375
    • Kim, Y.1    Choi, K.2    Jung, J.3    Park, S.4    Kim, P.G.5    Park, J.6
  • 23
    • 0026574816 scopus 로고
    • The role of oxyradicals in intracellular proteolysis and toxicity in mussels
    • Kirchin M.A., Moore M.N., Dean R.T., and Winston G.W. The role of oxyradicals in intracellular proteolysis and toxicity in mussels. Mar. Environ. Res. 34 (1992) 315-320
    • (1992) Mar. Environ. Res. , vol.34 , pp. 315-320
    • Kirchin, M.A.1    Moore, M.N.2    Dean, R.T.3    Winston, G.W.4
  • 27
    • 0034893348 scopus 로고    scopus 로고
    • Contaminant-stimulated reactive oxygen species production and oxidative damage in aquatic organisms
    • Livingstone D.R. Contaminant-stimulated reactive oxygen species production and oxidative damage in aquatic organisms. Mar. Pollut. Bull. 42 (2001) 656-666
    • (2001) Mar. Pollut. Bull. , vol.42 , pp. 656-666
    • Livingstone, D.R.1
  • 28
    • 0028072760 scopus 로고
    • Contaminant induced lysosomal membrane damage in marine mussel digestive cells: an in vitro study
    • Lowe D.M., and Pipe R.K. Contaminant induced lysosomal membrane damage in marine mussel digestive cells: an in vitro study. Aquat. Toxicol. 30 (1994) 357-365
    • (1994) Aquat. Toxicol. , vol.30 , pp. 357-365
    • Lowe, D.M.1    Pipe, R.K.2
  • 29
    • 26844550239 scopus 로고    scopus 로고
    • The neutral red lysosomal retention assay and comet assay on haemolymph cells from mussels (Mytilus edulis) and fish (Symphodus melops) exposed to styrene
    • Mamaca E., Bechmann R.K., Torgrimsen S., Aas E., Bjørnstad A., Baussant T., and Le Floch S. The neutral red lysosomal retention assay and comet assay on haemolymph cells from mussels (Mytilus edulis) and fish (Symphodus melops) exposed to styrene. Aquat. Toxicol. 75 (2005) 191-201
    • (2005) Aquat. Toxicol. , vol.75 , pp. 191-201
    • Mamaca, E.1    Bechmann, R.K.2    Torgrimsen, S.3    Aas, E.4    Bjørnstad, A.5    Baussant, T.6    Le Floch, S.7
  • 30
    • 0028098223 scopus 로고
    • Dicing with death: dissecting the components of the apoptosis machinery
    • Martin S.J., Green D.R., and Cotter T.G. Dicing with death: dissecting the components of the apoptosis machinery. Trends Biochem. Sci. 19 (1994) 26-30
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 26-30
    • Martin, S.J.1    Green, D.R.2    Cotter, T.G.3
  • 31
    • 0031841377 scopus 로고    scopus 로고
    • Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
    • Miners J.O., and Birkett D.J. Cytochrome P4502C9: an enzyme of major importance in human drug metabolism. Br. J. Clin. Pharmacol. 45 (1998) 525-538
    • (1998) Br. J. Clin. Pharmacol. , vol.45 , pp. 525-538
    • Miners, J.O.1    Birkett, D.J.2
  • 32
    • 0036227678 scopus 로고    scopus 로고
    • Antioxidant enzymes and peroxisome proliferation in relation to contaminant body burdens of PAHs and PCBs in bivalve molluscs, crabs and fish from the Urdaibai and Plentzia estuaries (Bay of Biscay)
    • Orbea A., Ortiz-Zarragoitia M., Solé M., Porte C., and Cajaraville M.P. Antioxidant enzymes and peroxisome proliferation in relation to contaminant body burdens of PAHs and PCBs in bivalve molluscs, crabs and fish from the Urdaibai and Plentzia estuaries (Bay of Biscay). Aquat. Toxicol. 58 (2002) 75-98
    • (2002) Aquat. Toxicol. , vol.58 , pp. 75-98
    • Orbea, A.1    Ortiz-Zarragoitia, M.2    Solé, M.3    Porte, C.4    Cajaraville, M.P.5
  • 33
    • 34247602015 scopus 로고    scopus 로고
    • Comparison of key enzymes in the zebra mussel, Dreissena polymorpha, the earthworm Allolobophora chlorotica and Chironomus riparius larvae
    • Osman A.M., and van Noort P.C.M. Comparison of key enzymes in the zebra mussel, Dreissena polymorpha, the earthworm Allolobophora chlorotica and Chironomus riparius larvae. Ecotoxicol. Environ. Saf. 67 (2007) 212-217
    • (2007) Ecotoxicol. Environ. Saf. , vol.67 , pp. 212-217
    • Osman, A.M.1    van Noort, P.C.M.2
  • 34
    • 33846572885 scopus 로고    scopus 로고
    • Differential responses of biomarkers in tissues of a freshwater mussel, Dreissena polymorpha, to the exposure of sediment extracts with different levels of contamination
    • Osman A.M., van den Heuvel H., and van Noort P.C.M. Differential responses of biomarkers in tissues of a freshwater mussel, Dreissena polymorpha, to the exposure of sediment extracts with different levels of contamination. J. Appl. Toxicol. 27 (2007) 51-59
    • (2007) J. Appl. Toxicol. , vol.27 , pp. 51-59
    • Osman, A.M.1    van den Heuvel, H.2    van Noort, P.C.M.3
  • 35
    • 0343314888 scopus 로고    scopus 로고
    • Detection of micronuclei in haemocytes of zebra mussel and ramshorn snail exposed to pentachlorophenol
    • Pavlica M., Klobucar G.I.V., Vetma N., Erben R., and Papeš D. Detection of micronuclei in haemocytes of zebra mussel and ramshorn snail exposed to pentachlorophenol. Mutat. Res. 465 (2000) 145-150
    • (2000) Mutat. Res. , vol.465 , pp. 145-150
    • Pavlica, M.1    Klobucar, G.I.V.2    Vetma, N.3    Erben, R.4    Papeš, D.5
  • 37
    • 0036753402 scopus 로고    scopus 로고
    • Oxidative stress in ecotoxicology: from the analysis of individual antioxidants to a more integrated approach
    • Regoli F., Gorbi S., Frenzilli G., Nigro M., Corsi I., Focardi S., and Winston G.W. Oxidative stress in ecotoxicology: from the analysis of individual antioxidants to a more integrated approach. Mar. Environ. Res. 54 (2002) 419-423
    • (2002) Mar. Environ. Res. , vol.54 , pp. 419-423
    • Regoli, F.1    Gorbi, S.2    Frenzilli, G.3    Nigro, M.4    Corsi, I.5    Focardi, S.6    Winston, G.W.7
  • 38
    • 0242319037 scopus 로고    scopus 로고
    • Integrating enzymatic responses to organic chemical exposure with total oxyradical absorbing capacity and DNA damage in the European eel Anguilla anguilla
    • Regoli F., Winston G.W., Gorbi S., Frenzilli G., Nigro M., Corsi I., and Focardi S. Integrating enzymatic responses to organic chemical exposure with total oxyradical absorbing capacity and DNA damage in the European eel Anguilla anguilla. Environ. Toxicol. Chem. 22 (2003) 2120-2129
    • (2003) Environ. Toxicol. Chem. , vol.22 , pp. 2120-2129
    • Regoli, F.1    Winston, G.W.2    Gorbi, S.3    Frenzilli, G.4    Nigro, M.5    Corsi, I.6    Focardi, S.7
  • 39
    • 37349046678 scopus 로고    scopus 로고
    • Evaluation of DNA damages induced by BDE-209 in haemocytes of Dreissena polymorpha using SCGE assay and MN test
    • Riva C., Binelli A., Cogni D., and Provini A. Evaluation of DNA damages induced by BDE-209 in haemocytes of Dreissena polymorpha using SCGE assay and MN test. Environ. Mol. Mutagen. 48 (2007) 735-743
    • (2007) Environ. Mol. Mutagen. , vol.48 , pp. 735-743
    • Riva, C.1    Binelli, A.2    Cogni, D.3    Provini, A.4
  • 40
    • 4444268080 scopus 로고    scopus 로고
    • Toxicity classification and evaluation of four pharmaceuticals classes: antibiotics, antineoplastics, cardiovascular and sex hormones
    • Sanderson H., Brain R.A., Johnson D.J., Wilson C.J., and Solomon K.R. Toxicity classification and evaluation of four pharmaceuticals classes: antibiotics, antineoplastics, cardiovascular and sex hormones. Toxicology 203 (2004) 27-40
    • (2004) Toxicology , vol.203 , pp. 27-40
    • Sanderson, H.1    Brain, R.A.2    Johnson, D.J.3    Wilson, C.J.4    Solomon, K.R.5
  • 41
    • 0037052833 scopus 로고    scopus 로고
    • Pharmacodynamic activity of drugs and ecotoxicology-can the two be connected?
    • Seiler J.P. Pharmacodynamic activity of drugs and ecotoxicology-can the two be connected?. Toxicol. Lett. 131 (2002) 105-115
    • (2002) Toxicol. Lett. , vol.131 , pp. 105-115
    • Seiler, J.P.1
  • 42
    • 0034693836 scopus 로고    scopus 로고
    • Microgels for estimation of DNA strand breaks, DNA protein crosslinks and apoptosis
    • Singh N.P. Microgels for estimation of DNA strand breaks, DNA protein crosslinks and apoptosis. Mutat. Res. 455 (2000) 111-127
    • (2000) Mutat. Res. , vol.455 , pp. 111-127
    • Singh, N.P.1
  • 43
    • 0023919963 scopus 로고
    • A simple technique for quantification of low levels of DNA damage in individual cells
    • Singh N.P., McCoy M.T., Tice R.R., and Schneider E. A simple technique for quantification of low levels of DNA damage in individual cells. Exp. Cell Res. 175 (1988) 184-191
    • (1988) Exp. Cell Res. , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.4
  • 44
    • 0029940299 scopus 로고    scopus 로고
    • Contribution of apoptosis to observed DNA damage in mussel cells
    • Steinert S.A. Contribution of apoptosis to observed DNA damage in mussel cells. Mar. Pollut. Bull. 42 (1996) 253-259
    • (1996) Mar. Pollut. Bull. , vol.42 , pp. 253-259
    • Steinert, S.A.1
  • 45
    • 0033664783 scopus 로고    scopus 로고
    • Substrate-dependent modulation of CYP3A4 catalytic activity: analysis of 27 test compounds with four fluorometric substrates
    • Stresser D.M., Blanchard A.P., Turner S.D., Erve J.C., Dandenau A.A., Miller V.P., and Crespi C.L. Substrate-dependent modulation of CYP3A4 catalytic activity: analysis of 27 test compounds with four fluorometric substrates. Drug Metab. Dispos. 28 (2000) 1440-1448
    • (2000) Drug Metab. Dispos. , vol.28 , pp. 1440-1448
    • Stresser, D.M.1    Blanchard, A.P.2    Turner, S.D.3    Erve, J.C.4    Dandenau, A.A.5    Miller, V.P.6    Crespi, C.L.7
  • 48
    • 33646791891 scopus 로고    scopus 로고
    • Molecular biomarkers of oxidative stress in aquatic organisms in relation to toxic environmental pollutants
    • Valavanidis A., Vlahogianni T., Dassenakis M., and Scoullos M. Molecular biomarkers of oxidative stress in aquatic organisms in relation to toxic environmental pollutants. Ecotoxicol. Environ. Saf. 64 (2006) 178-189
    • (2006) Ecotoxicol. Environ. Saf. , vol.64 , pp. 178-189
    • Valavanidis, A.1    Vlahogianni, T.2    Dassenakis, M.3    Scoullos, M.4
  • 49
    • 0029983030 scopus 로고    scopus 로고
    • Production of reactive oxygen species (ROS) by hemocytes from the marine mussel, Mytilus edulis
    • Winston G.W., Moore M.N., Kirchin M.A., and Soverchia C. Production of reactive oxygen species (ROS) by hemocytes from the marine mussel, Mytilus edulis. Comp. Biochem. Physiol. C 113 (1996) 221-229
    • (1996) Comp. Biochem. Physiol. C , vol.113 , pp. 221-229
    • Winston, G.W.1    Moore, M.N.2    Kirchin, M.A.3    Soverchia, C.4
  • 50
    • 34247350720 scopus 로고    scopus 로고
    • - content, and alterations in ultrastructures of FG cells, a flounder (Paralichthys olivaceus) gill cell line
    • - content, and alterations in ultrastructures of FG cells, a flounder (Paralichthys olivaceus) gill cell line. Toxicol. Mechan. Methods 17 (2007) 127-134
    • (2007) Toxicol. Mechan. Methods , vol.17 , pp. 127-134
    • Xiao, Q.1    Zhang, S.2    Guo, H.3    Su, F.4    Xu, Y.5
  • 51
    • 33947588994 scopus 로고    scopus 로고
    • Hepatoprotective and antioxidant effects of Cuscuta chinensis against acetaminophen-induced hepatotoxicity in rats
    • Yen F.-L., Wu T.-H., Lin L.-T., and Lin C.-C. Hepatoprotective and antioxidant effects of Cuscuta chinensis against acetaminophen-induced hepatotoxicity in rats. J. Ethnopharmacol. 111 (2006) 123-128
    • (2006) J. Ethnopharmacol. , vol.111 , pp. 123-128
    • Yen, F.-L.1    Wu, T.-H.2    Lin, L.-T.3    Lin, C.-C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.