Cell death and ultrastructural alterations in Leishmania amazonensis caused by new compound 4-Nitrobenzaldehyde thiosemicarbazone derived from S-limonene

BMC Microbiology

Volumn 14, Issue 1, 2014, Pages

  Britta, Elizandra Aparecida ^a   Scariot, Débora Botura ^a   Falzirolli, Hugo ^a   Ueda Nakamura, Tânia ^a   Silva, Cleuza Conceição ^a   Filho, Benedito Prado Dias ^a   Borsali, Redouane ^b   Nakamura, Celso Vataru ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

^b UNIV GRENOBLE ALPES   (France)

Author keywords

Antileishmanial activity; Benzaldehyde thiosemicarbazone; Cellular disorganization; Electron microscopy; Leishmania amazonensis; Mitochondria damage; Ultrastructural alterations

Indexed keywords

4 NITROBENZALDEHYDE THIOSEMICARBAZONE; ANTILEISHMANIAL AGENT; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; LIMONENE; LIPOCORTIN 5; PHOSPHATIDYLSERINE; THIOSEMICARBAZONE DERIVATIVE; UNCLASSIFIED DRUG; 4-NITROBENZALDEHYDE; ANTIPROTOZOAL AGENT; BENZALDEHYDE DERIVATIVE; CYCLOHEXENE DERIVATIVE; TERPENE;

AMASTIGOTE; ANTIPROTOZOAL ACTIVITY; ARTICLE; CELL DAMAGE; CELL DEATH; CELL MEMBRANE; CELL PROLIFERATION; CELL SHAPE; CELL SIZE; CELL STRAIN; CELL SURFACE; CELL ULTRASTRUCTURE; CELL VACUOLE; CELL VOLUME; CONTROLLED STUDY; CYTOTOXICITY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GROWTH INHIBITION; HISTOGRAM; HYDROPHOBICITY; IC50; LEISHMANIA; MACROPHAGE; MICROBIAL GROWTH; MITOCHONDRIAL MEMBRANE; NONHUMAN; OXIDATION; PROMASTIGOTE; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CELL LINE; CELL ORGANELLE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; DRUG SENSITIVITY; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; LEISHMANIA MEXICANA; MOUSE; ULTRASTRUCTURE;

LEISHMANIA AMAZONENSIS;

ANIMALS; ANTIPROTOZOAL AGENTS; BENZALDEHYDES; CELL DEATH; CELL LINE; CELL SURVIVAL; CYCLOHEXENES; INHIBITORY CONCENTRATION 50; LEISHMANIA MEXICANA; MACROPHAGES; MICE; ORGANELLES; PARASITIC SENSITIVITY TESTS; TERPENES; THIOSEMICARBAZONES;

EID: 84907812007     PISSN: None     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/s12866-014-0236-0     Document Type: Article

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