Further evidence of the trypanocidal action of eupomatenoid-5: Confirmation of involvement of reactive oxygen species and mitochondria owing to a reduction in trypanothione reductase activity

Free Radical Biology and Medicine

Volumn 60, Issue , 2013, Pages 17-28

  Lazarin Bidoia D ^a   Desoti, V C ^a   Ueda Nakamura, T ^a   Dias Filho, B P ^a   Nakamura, C V ^a   Silva, S O ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

Author keywords

Cell death; Eupomatenoid 5; Free radicals; Mitochondria; ROS; Trypanosoma cruzi; Trypanothione reductase

Indexed keywords

ANTITRYPANOSOMAL AGENT; EUPOMATENOID 5; PHOSPHATIDYLSERINE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; THIOL; TRYPANOTHIONE REDUCTASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CELL STRUCTURE; CELL VACUOLE; CELL VIABILITY; CELL VOLUME; CHAGAS DISEASE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG STRUCTURE; ENZYME ACTIVITY; LIPID PEROXIDATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

BENZOFURANS; CELL DEATH; CHAGAS DISEASE; FREE RADICALS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NADH, NADPH OXIDOREDUCTASES; OXIDATIVE STRESS; PHENOLS; PIPER; PLANT EXTRACTS; PLANT LEAVES; REACTIVE OXYGEN SPECIES; TRYPANOSOMA CRUZI;

PIPER REGNELLII; TRYPANOSOMA CRUZI;

EID: 84874936432     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.01.008     Document Type: Article

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