Benzaldehyde Thiosemicarbazone derived from limonene complexed with copper induced mitochondrial dysfunction in Leishmania amazonensis

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Britta, Elizandra Aparecida ^a   Barbosa Silva, Ana Paula ^a   Ueda Nakamura, Tânia ^a   Dias Filho, Benedito Prado ^a   Silva, Cleuza Conceição ^a   Sernaglia, Rosana Lázara ^a   Nakamura, Celso Vataru ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPARASITIC AGENT; BENZALDEHYDE THIOSEMICARBAZONE; COPPER; LIMONENE; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ANTILEISHMANIAL ACTIVITY; ARTICLE; CELL MEMBRANE; CELL SHAPE; CELL SIZE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; GROWTH INHIBITION; IC 50; LEISHMANIA; LIPID PEROXIDATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PROMASTIGOTE;

ANIMALS; ANTIPROTOZOAL AGENTS; BENZALDEHYDES; COPPER; HUMANS; LEISHMANIA; LEISHMANIASIS; LIPID PEROXIDATION; MACROPHAGES, PERITONEAL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED BALB C; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; OXIDATION-REDUCTION; SUPEROXIDES; THIOSEMICARBAZONES;

LEISHMANIA AMAZONENSIS; PROTOZOA;

EID: 84864749466     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041440     Document Type: Article

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