Trypanocidal action of (-)-elatol involves an oxidative stress triggered by mitochondria dysfunction

Marine Drugs

Volumn 10, Issue 8, 2012, Pages 1631-1646

  Desoti, Vânia Cristina ^a   Lazarin Bidóia, Danielle ^a   Sudatti, Daniela Bueno ^b   Pereira, Renato Crespo ^b   Alonso, Antonio ^c   Ueda Nakamura, Tania ^a   Dias Filho, Benedito Prado ^a   Nakamura, Celso Vataru ^a   De Silva, Sueli Oliveira ^a  

^a STATE UNIVERSITY OF MARINGÁ   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^c FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

Author keywords

( ) elatol; Chagas' disease; Mitochondria; Oxidative stress; Trypanosoma cruzi

Indexed keywords

ANTIMICYN A; ANTIPROTOZOAL AGENT; DIGITONIN; DNA; ELATOL; NATURAL PRODUCT; REACTIVE OXYGEN METABOLITE; SESQUITERPENE; SUPEROXIDE; UNCLASSIFIED DRUG; WORTMANNIN;

ANTIPROTOZOAL ACTIVITY; ARTICLE; AUTOPHAGY; BRAZIL; CELL MEMBRANE; CELL VACUOLE; CELL VOLUME; CHAGAS DISEASE; CONTROLLED STUDY; DRUG DEVELOPMENT; DRUG STRUCTURE; DRUG TARGETING; LAURENCIA; LAURENCIA DENDROIDEA; MACROALGA; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL DYSFUNCTION; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; RESPIRATORY CHAIN; SEASHORE; TRYPANOCIDAL ACTIVITY; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE;

DENDROIDEA; LAURENCIA; TRYPANOSOMA CRUZI;

EID: 84865998758     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md10081631     Document Type: Article

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