Amiodarone destabilizes intracellular Ca2+ homeostasis and biosynthesis of sterols in leishmania mexicana

Antimicrobial Agents and Chemotherapy

Volumn 53, Issue 4, 2009, Pages 1403-1410

  Xenon Serrano Martin ^a,b   Yael Garcia Marchan ^a,b   Alexis Fernandez, ^c   Noris Rodriguez, ^c   Hector Rojas, ^c   Gonzalo Visbal, ^c   Benaim, Gustavo ^a,b  

^a Instituto Internacional de Estudios Avanzados IDEA   (Venezuela)

^b FACULTAD DE CIENCIAS   (Venezuela)

^c INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

Author keywords

[No Author keywords available]

Indexed keywords

5 DEHYDROEPISTEROL; AMIODARONE; CALCIUM ION; SQUALENE; STEROL DERIVATIVE; UNCLASSIFIED DRUG;

AMASTIGOTE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL DISRUPTION; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FLUOROMETRY; HOST CELL; LEISHMANIA MEXICANA; MITOCHONDRION; NONHUMAN; PARASITE VIABILITY; PRIORITY JOURNAL; PROMASTIGOTE; STEROL SYNTHESIS;

AMIODARONE; ANIMALS; CALCIUM; CELLS, CULTURED; HOMEOSTASIS; LEISHMANIA MEXICANA; MACROPHAGES; MICE; MICROSCOPY, CONFOCAL; MITOCHONDRIA; STEROLS;

EID: 65649143532     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01215-08     Document Type: Article

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