Basis for substrate recognition and distinction by matrix metalloproteinases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 40, 2014, Pages E4148-E4155

  Ratnikov, Boris I ^a   Cieplak, Piotr ^a   Gramatikoff, Kosi ^a   Pierce, James ^a   Eroshkin, Alexey ^a   Igarashi, Yoshinobu ^a   Kazanov, Marat ^b   Sun, Qing ^a   Godzik, Adam ^a,c   Osterman, Andrei ^a,c   Stec, Boguslaw ^a   Strongin, Alex ^a,c   Smith, Jeffrey W ^a  

^a Cancer Center   (United States)

^b INSTITUTE FOR INFORMATION TRANSMISSION PROBLEMS   (Russian Federation)

^c BURNHAM INSTITUTE   (United States)

Author keywords

MMPs; Protease |; Specificity determining positions |

Indexed keywords

MATRIX METALLOPROTEINASE; PEPTIDE;

ALGORITHM; AMINO ACID SEQUENCE; BINDING SITE; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PHYLOGENY; PROTEIN DEGRADATION; SEQUENCE HOMOLOGY;

ALGORITHMS; AMINO ACID SEQUENCE; BINDING SITES; BIOCATALYSIS; CATALYTIC DOMAIN; HUMANS; KINETICS; MATRIX METALLOPROTEINASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PHYLOGENY; PROTEOLYSIS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 84907687810     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1406134111     Document Type: Article

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