Targeting RPTPσ with lentiviral shRNA promotes neurites outgrowth of cortical neurons and improves functional recovery in a rat spinal cord contusion model

Brain Research

Volumn 1586, Issue , 2014, Pages 46-63

  Zhou, Heng Xing ^a   Li, Xue Ying ^a   Li, Fu Yuan ^a   Liu, Chang ^b   Liang, Zhi Pin ^b   Liu, Shen ^a   Zhang, Bin ^a   Wang, Tian Yi ^a   Chu, Tian Ci ^a   Lu, Lu ^a   Ning, Guang Zhi ^a   Kong, Xiao Hong ^b   Feng, Shi Qing ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b NANKAI UNIVERSITY   (China)

Author keywords

Axon regeneration; Functional recovery; RNA interference; RPTP ; Spinal cord injury

Indexed keywords

LENTIVIRUS VECTOR; PROTEIN TYROSINE PHOSPHATASE; RECEPTOR PROTEIN TYROSINE PHOSPHATASE SIGMA; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; ENHANCED GREEN FLUORESCENT PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; GREEN FLUORESCENT PROTEIN; RECEPTOR LIKE PROTEIN TYROSINE PHOSPHATASE; SMALL INTERFERING RNA; TUBULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL; CONTROLLED STUDY; CONTUSION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LENTIVIRINAE; NERVE FIBER GROWTH; NERVE FIBER REGENERATION; NEURITE; NONHUMAN; RAT; RNA INTERFERENCE; SCAR FORMATION; SPINAL CORD; SPINAL CORD INJURY; SYNAPSE; ANIMAL; BRAIN CORTEX; CELL CULTURE; CONVALESCENCE; CYTOLOGY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; NERVE CELL; NERVE REGENERATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPINAL CORD INJURIES; TIME; WISTAR RAT;

RATTUS;

ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; GREEN FLUORESCENT PROTEINS; NERVE REGENERATION; NEURITES; NEURONS; RATS; RATS, WISTAR; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 2; RECOVERY OF FUNCTION; RNA, SMALL INTERFERING; SPINAL CORD INJURIES; TIME FACTORS; TRANSFECTION; TUBULIN;

EID: 84907669198     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2014.08.048     Document Type: Article

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