The meganuclease I-SceI containing nuclear localization signal (NLS-I-SceI) efficiently mediated mammalian germline transgenesis via embryo cytoplasmic microinjection

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Wang, Yong ^a   Zhou, Xiao Yang ^a   Xiang, Peng Ying ^a   Wang, Lu Lu ^a   Tang, Huan ^b   Xie, Fei ^a   Li, Liang ^a   Wei, Hong ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b China Three Gorges Museum   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; MESSENGER RNA; NUCLEAR LOCALIZATION SIGNAL; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE;

ANIMAL EXPERIMENT; ARTICLE; BIOSAFETY; CONTROLLED STUDY; CYTOPLASM; DNA TRANSFER; EGG; EMBRYO; EMBRYO CYTOPLASMIC MICROINJECTION; FEMALE; GENE EXPRESSION; GENE SEQUENCE; GERM LINE; I SCEI GENE; MICROINJECTION; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PLASMID; PORCINE EMBRYO; TRANSGENE; TRANSGENICS; ANIMAL; ANIMAL EMBRYO; EMBRYO CULTURE; EMBRYOLOGY; GENE TRANSFER; GENETICS; METABOLISM; MINIPIG; OOCYTE; PIG; PROCEDURES; TRANSGENIC ANIMAL; VETERINARY;

MAMMALIA;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CYTOPLASM; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; EMBRYO CULTURE TECHNIQUES; EMBRYO, MAMMALIAN; FEMALE; GENE TRANSFER TECHNIQUES; MICE; MICROINJECTIONS; NUCLEAR LOCALIZATION SIGNALS; OOCYTES; SWINE; SWINE, MINIATURE;

EID: 84907588658     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108347     Document Type: Article

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